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URL: http://www.biocomputing.it/digit/index.php
Proper Citation: DIG IT - Database of Immunoglobulins and Integrated Tools (RRID:SCR_005924)
Description: The Database of Immunoglobulins and Integrated Tools (DIG IT) is an integrated resource storing sequences of annotated immunoglobulin variable domains of NCBI database and enriched with tools for searching and analyzing them. It contains 145759 heavy chain sequences and 71404 light chain sequences (47168 kappa type and 24236 lambda type) with assigned canonical structures for the hypervariable loops and the data on the type of antigen as well as the pairing information of immunoglobulin heavy and light chains (9672 total pairs). The user can input the immunoglobulin variable domain sequence (amino acid or nucleotide) of interest (heavy chain variable domain sequence; light chain variable domain sequence or both) to retrieve the closest sequences (sorted according to e-value) with complete annotation. The user can also directly query the database by antigen type, canonical structure, germline family in accordance to the requirements.
Abbreviations: DIG IT, DIGIT
Synonyms: Database of Immunoglobulins and Integrated Tools, DIG IT! Database of Immunoglobulins and Integrated Tools, DIG IT! Database of Immunoglobulins with Integrated Tools, Database of Immunoglobulins Integrated Tools, DIG IT! Integrated Ig Database, DIG IT - Database of Immunoglobulins Integrated Tools
Resource Type: analysis service resource, data analysis service, data or information resource, database, production service resource, service resource
Defining Citation: PMID:22080506
Keywords: sequence, immunoglobulin, variable domain, domain, heavy chain sequence, light chain sequence, antigen type, canonical structure, germline family, blast
Funding: IIT SEED ; King Abdullah University of Science and Technology KUK-I1-012-43; Ministry of Health Contract Onc_Ord 25/07
Availability: The results obtained from the server shall be used for scientific purposes only, Excluding industrial or commercial purposes. Proper acknowledgement shall be made to the author of the server in publications resulting from the use of it. The results of the server shall not be made available to users outside the recipient''''s laboratory, Unless written consent is obtained.
Resource Name: DIG IT - Database of Immunoglobulins and Integrated Tools
Resource ID: SCR_005924
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Source: SciCrunch Registry (RRID:SCR_005400)
Description: Interactive portal for finding and submitting biomedical resources. Resources within SciCrunch have assigned RRIDs which are used to cite resources in scientific manuscripts. SciCrunch Registry, formerly NIF Registry, provides resources catalog. Allows to add new resources. Allows edit existing resources after registration. Curators are tasked with identifying and registering resources, examining data, writing configuration files to index and display data and keeping contents current.
URL: https://rrid.site/rin/sources/SCR_005400
Data set from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings."
