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URL: http://www.addgene.org/171218
Proper Citation: RRID:Addgene_171218
Insert Name: AR-AAFF
Organism: Homo sapiens
Bacterial Resistance: Ampicillin
Defining Citation: PMID:34911936
Vector Backbone Description: Backbone Size:10000; Vector Backbone:Lenti-viral-Hygro; Vector Types:Mammalian Expression, Lentiviral; Bacterial Resistance:Ampicillin
Comments: The mutations occur on the androgen receptor KVFF motif in the P-box of the zinc finger 1 that make contact with DNA. AR mutants of the KVFF motif would lose activity to activate AR-mediated transcription. Please Note: This plasmid contains a 6x Gln deletion in the 23x Gln track and a 8x Gly deletion in the 23x Gly track in androgen receptor compared to the depositor's provided sequence. These differences are not known to affect the function of the protein.
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Source: Addgene
Data set from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings."
