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NIDDK Information Network (dkNET) curated a list of community-based funding opportunities provided by projects or organizations other than government granting agencies (such as NIH or NSF), e.g., pilot projects, training opportunities.

(last updated: Dec 7, 2022)

Funding Grants

138 Results - per page

TitleDescriptionProgramAward AmountPosted DateClose DateDuration
Baylor College of Medicine Pilot and Feasibility ProgramBaylor College of MedicineUp to $50,0001-2 years
Studies to advance and translate our understanding of nuclear receptor (NR) and coregulator biology and physiology to influence disease outcomes.NURSA$150,0002014-05-25
Nuclear Receptors in ENCODENuclear receptors and their co-associated proteins regulate gene expression in a tissue, cell, ligand and time specific manner. NRs bind to DNA in the context of chromatin patterns and cell specific gene regulation is mediated through the use of different combinations of epigenetic features. The ENCODE project has assigned biochemical function to 80% of the human genome and the publically available database provides a rich source of integrative data. Applications for this topic combined nuclear receptor expertise with bioinformatics expertise for mining the datasets available from ENCODE, thus allowing the elucidation of NR-specific signaling in a context that is relevant to metabolic or reproductive disease.NURSA$150,0002013-06-012013-12-311-2 years
Nuclear Receptor Signaling Atlas (NURSA) Hub Open Competition for NURSA Data Source Projects (NDSP)The mission of the NuclearReceptor Signaling Atlas (NURSA) is to accrue, develop, and communicateinformation advancing our understanding of the integral role of nuclearreceptor signaling in physiology and metabolic diseases, including diabetes, obesity,and reproductive diseases and disorders. Currently, the central core of NURSA isa Hub that provides the integration and cohesion needed to aggregate, annotate,and present state-of-the-art data in a user friendly fashion. A web portal, www.nursa.org, interfaces with the broaderscientific community. To achieve its goals, the NURSA Informatics Hub solicits Projectapplications to support innovative research to the Hub. Successful PIs willleverage their individual and collaborative resources to address the scientificgoals of this Request for Applications. Three previous similar announcementsresulted in 11 NURSA-funded projects that support high quality cross-cutting research. The NR community hasgenerated a large number of omics-scale datasets that collectively document functionalendpoints of NR signaling pathways throughout the body. Despite their potentialin elucidating NR signaling in health and disease, these datasets have yet tobe leveraged to their full potential. Accordingly,the NURSA Hub has invested considerable effort in aggregating, annotating, curating,and processing these datasets to enhance their use. The full current list ofdatasets can be browsed on the NURSADataset home page,or the resource’s 40,000,000+ data points can be mined via Transcriptomine.To fully capitalize on this significant investment of knowledge and expertise, thisNDSP announcement solicits applications based on the following goals:(1)Extend Transcriptomine by building newvisualization and analysis tools. (2) Leverage the Transcriptomine API to build webapplications that will reach research communities beyond the nuclear receptorfield. (3) Improve the scope of Transcriptomine throughbiocuration of complementary ‘omics-scale datasets. Successfulapplications will have a substantial informatics focus and relevance to thephysiology and/or pathophysiology of metabolic disease. Unlike previoussolicitations, and recognizing integrative cross-talk between differentsignaling paradigms, applications need not themselves relate specifically tonuclear receptor signaling. Where appropriate, applicants are encouraged to usethe Transcriptomine application programming interface (API). Applications thatpropose active collaboration with the NURSA Informatics Hub are particularlywelcome, and discussions with the NURSA Project Scientist Dr. Corinne Silva (silvacm@niddk.nih.gov) or the NURSAProject Leader Dr. Neil McKenna (nmckenna@bcm.edu)prior to submission of proposals are strongly encouraged. Deadline for letter of intent: November 7, 2016.NURSA$150,0002016-10-192016-11-201 year
Generation of potentially novel NR ligands that can be applied in chemical biology studies to better understand NR mechanism of action.NURSA$150,0002014-05-25
The University of Pennsylvania Diabetes Research Center Pilot and Feasibility Grant ProgramThe P&F program is particularly directed at new investigators and established investigators new to diabetes research. Established diabetes investigators pursuing high impact/high-risk projects or projects that are a significant departure from their usual work are also eligible for support under the DRC P&F program. Applications are welcome from basic, clinical and translational investigators. Eligibility: Applications are invited from the Penn DRC community each fall.The University of Pennsylvania Diabetes Research Center$50,0002020-04-012021-12-061 year
Joslin Diabetes Research Foundation Beta Cell Replacement Innovation Awards

JDRF provides seed funding for highly innovative research with significant potential to accelerate the mission of JDRF. Proposals should address key outstanding questions and have the potential to lead to a change in the current paradigm or conventional wisdom and/or lead to a groundbreaking discovery. Preliminary data is not required in the proposal but the underlying premise, goal, or hypothesis must be plausible and testable and the proposal must be focused with a well- defined goal that is achievable within the timeframe of the award. The JDRF Beta Cell Replacement program strategy is designed to achieve the ultimate goal of creating a product with a safe renewable beta cell source capable of restoring glucose control and delivering long-term insulin independence without the need for chronic immunosuppression therapy. Priority areas include (1) Cell source: Identify the best cell source and composition;Reprogram somatic cells in vitro to functional insulin-producing cells;Leverage early clinical trial data to improve next-generation products (2)Cell survival and immune protection:Bioengineered delivery devices (encapsulation, scaffolds, hydrogels); Strategies to mitigate fibrosis and increase oxygenation; Beta cell survival agents to help preserve graft function; Device-less approaches include cell modification by genome editing and combination of immune and beta cell replacement therapies (3) Accelerate clinical translation: Standardize reagents: define preclinical animal models most predictive of human responses;Establish implantation site: engineer extrahepatic implantation sites to promote engraftment via scaffolds.

Joslin Diabetes Research Foundation$100,0002018-10-311 year
UCLA AIDS Institute / UCLA CHIPTS / UCLA Pediatrics AIDS Coalition Pediatric HIV ResearchThe UCLA AIDS Institute is accepting applications for seed grants to fund basic and clinical pilot research studies relevant to pediatric HIV infection. The grants will be funded by the Pediatric AIDS Coalition at UCLA, through proceeds from the annual Dance Marathon. Letter of Intent due March 15, 2021.UCLA AIDS InstituteUp to $50,0002021-05-102 years
Harvard University Digestive Disease Center Pilot and Feasibility ProgramThe HDDC is focused on the study of epithelial cell function and mucosal biology in inflammation, host defense, and cancer of the gastrointestinal tract and related mucosal surfaces. Pilot & Feasibility projects will be considered for support if they relate directly or indirectly to this mission. Letter of Intent Deadline: December 27, 2021.Harvard University Digestive Disease Center$25,0002022-02-211 year
Autoimmune Liver Diseases Pilot Research AwardThe purpose of this one year, $20,000 award is to provide supplementary funding during the pilot phase of basic, translational or clinical research projects in autoimmune liver disease (e.g. autoimmune hepatitis, primary sclerosing cholangitis, primary biliary cholangitis) in preparation for future grant applications by the recipient. Projects should address focused research questions pertaining to the pathogenesis, diagnosis, management or outcome of autoimmune liver diseases in children and adults.American Association for the Study of Liver Disease$20,0002021-12-021 year
dkNET New Investigator Pilot Program

Bioinformatics is an interdisciplinary field that applies quantitative sciences concepts and computational methods to advance our understanding of biological data and principles. Acquiring bioinformatics expertise will be important for many new DEMD investigators who need to manage large datasets and to leverage associated databases and analytical pipelines to solve contemporary biomedical problems. On the other hand, investigators with existing bioinformatics expertise will need to develop an in-depth knowledge of the biological systems and disease processes that underlie the data to design relevant and practical approaches. In the future, having cross-disciplinary expertise in both laboratory and quantitative biology will be important for formulating relevant questions, for developing, choosing, and assembling the proper analytical techniques, and for interpreting and presenting the outcomes in a meaningful and impactful way. The goal of the dkNET Pilot Award program is to provide support for Early Stage and New Investigators seeking to apply computationally-intensive methods to important questions in diabetes, endocrinology and metabolic diseases research. These awards will provide funding for preliminary studies that can serve as a foundation for the development of future grant applications in DEMD-focused topic areas.

dkNET Pilot Award applications should focus on applying computational and/or modeling approaches, whether data-driven, mechanism-driven, or integrated, to compelling research problems in diabetes, endocrinology and related metabolic disorders. Consistent with these goals, this program will support projects focused on a wide array of topics including, but not limited to:

  • Metabolic modeling of known and unknown pathway kinetics and compartmentalization in diabetes and/or endocrine or metabolic disorders;
  • Network and systems biology of intra and intercellular regulation and inter-tissue and organ homeostasis focused on etiology, diagnosis, prognosis or responses to treatment, including computational approaches to identify biomarkers capable of tracking disease process or progress;
  • Structural biology/informatics and chemical informatics of endocrine and metabolic pathways in diabetes, endocrinology and related metabolic diseases;
  • AI-assisted image analysis and spatial omics of organs or tissues of relevance to diabetes or metabolic disease;
  • Computational characterization of the normal or abnormal development of involved organs such as the formation of pancreatic islets;
  • Innovative approaches to characterize and understand type 2 diabetes heterogeneity;
  • Clinical informatics including curation, modeling and integration of data from EHR, medical devices, wearables and smartphone apps in diabetes prevention, care and management;
  • Data science approaches to understand, reduce, and prevent diabetes-related health disparities, including new analysis through social networks and structure;
  • The mechanisms for dysregulated glycemia, or diabetes in increased susceptibility or altered course of COVID-19 infection, and for metabolic dysfunction, diabetes, or other endocrine diseases that result from COVID-19 infection.

Of particular interest are projects that can leverage and expand the utility of existing large datasets developed in NIDDK projects and programs. For examples, see the dkNET webpage at NIDDK-specific-repositories. Research designed to address important research questions through the development of new analytical tools, or through novel secondary analyses of existing datasets are encouraged. Letter of Intent Due Date: January 28, 2022

The NIDDK Information Network (dkNET), University of California San DiegoLimited to $225,000 direct costs over the lifetime of the award (Up to 2 years)2019-11-012022-02-28up to 2 years
Columbia University Medical Center Diabetes Research Center Pilot Feasibility GrantsThe Columbia Diabetes Research Center (DRC) announces the availability of Pilot and Feasibility grants to support diabetes-related research at Columbia University. Letter of Intent deadline: November 1, 2021.Columbia University Medical CenterUp to $50,0002022-11-221-2 years
Pediatric Center of Excellence in Nephrology (PCEN) at the University of Virginia (UVA) Pilot and Feasibility Project

The Pediatric Center of Excellence in Nephrology (PCEN) at the University of Virginia (UVA) calls for applications for Pilot and Feasibility Projects (PFPs) within the general theme of the Center “Kidney Development: cell fate and precursors of disease in the young and adult”. The overall objective of the center is to improve the management of children with kidney diseases and hypertension. Although the central theme of the center is related to the developmental basis of kidney disease in children, applications proposing fundamental technological advances to solve major mechanisms or develop novel therapeutic strategies will be welcome. Letter of Intent Deadline: June 20, 2019.

Pediatric Center of Excellence in Nephrology (PCEN) at the University of Virginia (UVA)Up to $40,0002019-08-011-2 years
Nuclear Receptors and Gut MicrobiomeIt has become increasingly well-appreciated that the gut microbiome plays an integral role in the course of metabolic disease. Proposals for this topic investigate the role of NRs and NR signaling in mediating effects of the gut microbiome on intestinal physiology, barrier function, and inflammation. Integrate metagenomics, microbial metabolomics, gnotobiotic, and/or transgenic approaches to identify specific bacterial factors that act via nuclear receptors in the intestine and/or define NR-dependent changes in intestinal function due to alterations in the gut microbiome.NURSA$150,0002013-01-012013-12-31
MMPC MICROMouse ProgramMICROMouse will fund high impact technology-, physiology-, or biology-based projects conceived through interaction with, or between MMPCs. Proposal objectives should take clear advantage of collaborations with MMPCs to address questions that would be otherwise difficult to answer. Objectives of the MICROMmouse initiative encompasses pilot and feasibility projects for the development of new mouse phenotyping tests, as well as research-driven projects that investigate biology and physiology of disease.The aim of the MICROMouse program is to promote the development of mouse phenotyping technology and encourage collaborative relationships between the MMPC and its users. These are 1 year awards intended to fund the development of research opportunities that may arise during the course of a service provided by the MMPC or to expand on research interests common to a MMPC user and a MMPC principal investigator. These awards cannot be used simply to purchase services from an MMPC. There is no formal deadline associated with MICROMouse applications, but applications will be reviewed quarterly (March 1, June 1, September 1, December 1) and so should be submitted accordingly. A letter of intent with a brief (2-3 sentences) description of the proposed project must be sent to Dr. Richard McIndoe at rmcindoe@gru.edu at least two weeks prior to submission of an application.MMPC$75,0002015-09-012020-09-011 year
AASLD Pilot Research AwardThe American Association for the Study of Liver Disease (AASLD) Foundation Pilot Research Award supports highly innovative research ideas that have a clear potential to produce high-impact results, but have little or no preliminary data to successfully compete for funding from other sources. Applicant must be at the post-doctoral level (MD, PhD, PharmD or equivalent), or faculty at or below the rank of Associate Professor in an accredited North American (US, Canada, or Mexico) academic institution at the award start date.The American Association for the Study of Liver Disease Foundation$50,0002021-12-021 year
DiaComp Pilot and Feasibility ProgramThis program solicits and funds small Pilot and Feasibility (P&F) projects in high impact areas of complications research. Specifically, this program aims to support discovery (hypothesis generating) and innovative (high risk/ high reward) research that is increasingly difficult to support through standard NIH mechanisms. Basic, translational and clinical research proposals are encouraged. Research involving human subjects is limited to observational studies with non-invasive or minimally invasive testing and must have IRB approval that includes the collection and use of human samples for research purposes. Interventional clinical trials are beyond the scope of this program. Awards are expected to prepare the applicant(s) to submit a future investigator initiated project (e.g. NIH R01). Lower priority will be given to applicants who have received DiaComp support in the past three years. Foreign applications are NOT allowed.DiaComp$100,0002017-01-122021-04-161 year
Vanderbilt Digestive Disease Research Center Pilot ProjectThe Pilot and Feasibility Project Program (P/F) is designed to provide Vanderbilt investigators the opportunity to explore nascent, meritorious hypotheses related to digestive diseases with the ultimate goal being acquisition of external funding. The Vanderbilt Digestive Disease Research Center (VDDRC) plans to fund pilot projects annually. Awards will be made for 1-2 years in duration. Letter of Intent deadline: January 10, 2022Vanderbilt Digestive Disease Research Center$40,0002015-01-052022-03-081 year
Boston Area Diabetes Endocrinology Research Center Pilot GrantsThe Boston Area Diabetes Endocrinology Research Center is funded by the National Institute of Diabetes and Digestive Diseases (NIDDK) to support research in Diabetes and its complications. Letter of Intent: November 1, 2019Boston Area Diabetes Endocrinology Research CenterUp to $30,0002020-12-09unknown
West Coast Metabolomics Center - Pilot and Feasibility ProjectsThe WCMC provides extensive services for metabolomics research. The goal of the Pilot and Feasibility Program is to enhance metabolomics research crucial to translational projects by providing support for investigators new to the metabolomics field, the development of new teams and partnerships, projects that link genomics, proteomics and metabolomics, and high risk/high impact research. The Pilot and Feasibility Program aims to form new multidisciplinary collaborations that will enhance the integration of new techniques that benefit multiple investigators. Potential applicants are encouraged to link basic, translational, and clinical researchers. Extending the collaborative nature of research projects by matching funds from other mechanisms is encouraged.West Coast Metabolomics Center$50,0002018-03-231 year
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