Leaving Community
Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.
Source
Beta Cell Biology Consortium
THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone., documented on August 1, 2015. Consortium that aims to facilitate interdisciplinary collaborations to advance the understanding of pancreatic islet development and function, with the goal of developing innovative therapies to correct the loss of beta cell mass in diabetes, including cell reprogramming, regeneration and replacement. They are responsible for collaboratively generating the necessary reagents, mouse strains, antibodies, assays, protocols, technologies and validation assays that are beyond the scope of any single research effort. The scientific goals for the BCBC are to: * Use cues from pancreatic development to directly differentiate pancreatic beta cells and islets from stem / progenitor cells for use in cell-replacement therapies for diabetes, * Determine how to stimulate beta cell regeneration in the adult pancreas as a basis for improving beta cell mass in diabetic patients, * Determine how to reprogram progenitor / adult cells into pancreatic beta-cells both in-vitro and in-vivo as a mean for developing cell-replacement therapies for diabetes, and * Investigate the progression of human type-1 diabetes using patient-derived cells and tissues transplanted in humanized mouse models. Many of the BCBC investigator-initiated projects involve reagent-generating activities that will benefit the larger scientific community. The combination of programs and activities should accelerate the pace of major new discoveries and progress within the field of beta cell biology.
Details
- Resource Type: Resource, organization portal, resource, organism supplier, antibody supplier, database, biomaterial supply resource, biospecimen repository, experimental protocol, consortium, narrative resource, material resource, service resource, portal, storage service resource, cell repository, reagent supplier, data repository, material storage repository, data or information resource
- Keywords: pancreatic islet, mouse, beta cell, pancreas, pancreatic development, embryonic stem cell, cell line, genomics, antibody, adenovirus, functional genomics, mouse embryonic stem cell line, mouse strain, protocol, embryonic stem cell line, data sharing, data set, gene expression, gene, pancreatic islet development, pancreatic islet function, basic science, basic research, cell reprogramming, cell regeneration, cell replacement
- Resource ID: SCR_005136
- Proper Citation: ( Beta Cell Biology Consortium , RRID:SCR_005136)
- Parent Organization: Vanderbilt University; Tennessee; USA
- Related Condition: Type 1 diabetes, Diabetes
- Funding Agency: NIDDK
- Relation: related to: dkCOIN , Karolinska Institutet, Stockholm, Sweden, University of California at Los Angeles, California, USA, Stanford University, Stanford, California, University of Massachusetts Medical School, Massachusetts, USA, Hebrew University Hadassah Medical School, Jerusalem, Israel, Philipps-University Marburg, Marburg, Germany, Imperial College London, London, United Kingdom, Childrens Hospital of Philadelphia - Research Institute, Pennsylvania, USA, Icahn School of Medicine at Mount Sinai, New York, USA, University of California at San Francisco, California, USA, Massachusetts Institute of Technology, Massachusetts, USA, Hadassah Medical Center, Jerusalem, Israel, DanStem, Oregon Health and Science University, Oregon, USA, Vanderbilt University, Tennessee, USA, University of Chicago, Illinois, USA, University of Massachusetts, Massachusetts, USA, University of Colorado Boulder, Colorado, USA, Vrije Universiteit Brussel, Brussels, Belgium, University of Geneva, Geneva, Switzerland, University of Pennsylvania Perelman School of Medicine, Pennsylvania, USA, McEwen Centre for Regenerative Medicine, Seattle Childrens Research Institute, Washington, USA, Columbia University, New York, USA, University of Texas Southwestern Medical Center, Texas, USA, Hagedorn Research Institute, Gentofte, Denmark, Howard Hughes Medical Institute, Northwestern University, Illinois, USA, CAMRD, French National Center for Scientific Research, University of California at San Diego, California, USA, University of Pittsburgh, Pennsylvania, USA, University of Copenhagen, Copenhagen, Denmark, Jackson Laboratory, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany, Indiana University, Indiana, USA, University of Toronto, Ontario, Canada, Harvard University, Cambridge, United States, Harvard Medical School, Massachusetts, USA, Integrated Manually Extracted Annotation, used by: NIF Data Federation, Integrated Animals, NIDDK Information Network (dkNET), listed by: One Mind Biospecimen Bank Listing, re3data.org, Consortia-pedia, NIDDK Information Network (dkNET), NIDDK Research Resources
- Reference:
- Website Status: Last checked up
- Alternate IDs: nlx_144143
- Alternate URLs:
- Old URLs: http://www.betacell.org/,
- v_uuid: c3839136-b3c0-5dce-bffa-7f55d3f673ee
