Data updates for CKiD Study, PROBE Study, LOGIC, START At NIDDK Central Repository

Here is the data updates news from NIDDK Central Repository:

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1. CkiD (the Chronic Kidney Disease in Children ) study: The data package now includes data through December 2015. The CKiD study is a prospective cohort study of children with chronic kidney disease (CKD) that investigates risk factors and outcomes of the disease. The CKiD study had various objectives, including: (1) identifying and quantifying novel and traditional risk factors for progression of CKD; (2) characterizing how CKD progression effects neurodevelopment, cognitive abilities, and behavior; (3) describing the prevalence of cardiovascular disease and associated risk factors; and (4) examining the effects of declining kidney function on growth in children with CKD.

2. PROBE (the Prospective Database of Infants With Cholestasis) Study: The data package now includes an additional analysis dataset (Superina) from a publication. PROBE is a multi-center project to establish a prospective database of clinical information and a repository of blood and tissue samples from children with diagnoses of neonatal liver diseases, such as biliary atresia and neonatal hepatitis, in order to perform research in these liver problems.

3. LOGIC (the Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis) Study: The data package now includes analysis datasets (PedsQL) from a publication. LOGIC is a observational study with the objectives to determine the frequency of poor growth and decreased bone mineral density and its predictors; identify modifier genes that influence the incidence, severity, and progression of liver disease among affected individuals; and develop a repository of biospecimens to be used in ancillary studies of predictor biomarkers.

4. START (the Steroids in the Treatment of Biliary Atresia) Study: The data package now includes analysis datasets (Bezerra) from a publication. START is a clinical trial with the objective to determine the efficacy of corticosteroids on the outcome of infants with biliary atresia. "

Source information:

https://repository.niddk.nih.gov/news/#post-113
https://repository.niddk.nih.gov/news/#post-114
https://repository.niddk.nih.gov/news/#post-116
https://repository.niddk.nih.gov/news/#post-117