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dkNET community events and announcements in June, 2019

dkNET community events and announcements in June, 2019

Dear dkNET Community,

dkNET provides updates on activities of interest to the NIDDK-supported community. You could keep up to date on these activities through our Twitter feed @dkNET_info, through our Community Calendar, or through dkNET e-mail list. If you have an event or funding opportunities you'd like to advertise, please contact us info_at_dknet.org.


Events in June, 2019

Jun. 3-4, 2019 

NIDDK Workshop: The Physiology of the Weight Reduced State

The overarching goal of this workshop is to explore the mechanisms and integrative physiology of adaptations in appetite, energy expenditure, and thermogenesis (metabolic adaptation) that occur in the weight reduced state and may oppose weight loss maintenance.
The workshop will include: (1)Clinical experience with weight reduction and weight loss maintenance versus regain across interventions (2)Factors opposing weight loss maintenance (3)Factors affecting energy intake in the weight reduced state, including neural and endocrine regulation and the integration of homeostatic and hedonic pathways along with microbiome links (4)Metabolic adaptation/adaptive thermogenesis and tissue-specific roles and mechanisms(5)Strategies for understanding the physiology of the weight reduced state and improving weight loss maintenance (6)Factors potentially responsible for physiological variability in weight maintenance versus regain. Registration deadline: May 25, 2019.

Location:  Bethesda, MD, USA

More information:    https://www.niddk.nih.gov/news/meetings-workshops/2019/physiology-of-weight 

Jun. 5, 2019 

Abstract submission deadline: 2nd Annual UBCO Diabetes Research Day

The BC Diabetes Research Network invites academic faculty and their trainees to the 2nd Annual UBCO Diabetes Research Day. This exciting knowledge exchange event highlights the excellent research being conducted across BC. The meeting is focused on prevention and translational diabetes research. All attendees are invited to submit an abstract to deliver an oral presentation or present a poster. Abstract submission deadline: June 5, 2019.

Location:  Kelowna, BC, Canada

More information:    https://www.diabetesBC.ca 

Jun. 7-11, 2019 

American Diabetes Association (ADA) 79th Scientific Sessions

The Scientific Sessions offers researchers and health care professionals an amazing opportunity to share ideas and learn about the significant advances in diabetes research, treatment, and care. Over the course of five days, attendees will receive exclusive access to more than 2,800 original research presentations, take part in provocative and engaging exchanges with leading diabetes experts, and expand professional networks with over 14,000 attendees from around the world. Program Topics: • Acute and Chronic Complications • Behavioral Medicine, Clinical Nutrition, Education, and Exercise • Clinical Diabetes/Therapeutics • Epidemiology/Genetics • Immunology/Transplantation • Insulin Action/Molecular Metabolism • Integrated Physiology/Obesity • Islet Biology/Insulin Secretion

Location:  San Francisco, CA, USA

More information:    https://professional.diabetes.org/scientific-sessions 

Jun. 16-21, 2019 

Gordon Research Conference: Understanding Cell Behavior and Environmental Influences in Pancreatic Disease

The conference will consist of nine sessions, on the topics listed below:
  • Environmental Influences on Pancreatic Tissue Homeostasis
  • Role of the Microenvironment in Pancreatic Disease
  • Innovative In Vivo and In Vitro Models
  • Genetics of Pancreatic Diseases
  • Cell Plasticity in the Pancreas
  • Cell-Cell Communication in Pancreatic Homeostasis and Disease
  • Immune Cell-Tissue Cell Interactions
  • Signaling Cascades in Pancreatic Physiology and Pathology
  • Cell Programming and Reprogramming in the Pancreas
Applications for this meeting must be submitted by May 19, 2019. Please apply early, as some meetings become oversubscribed (full) before this deadline.

Location:  Newry, ME 04261, USA

More information:    https://www.grc.org/pancreatic-diseases-conference/2019/ 

Jun. 19-20, 2019 

NIH Pathway to Prevention (P2P) Workshop: Achieving Health Equity in Preventive Services

This P2P workshop will assess the available scientific evidence on achieving health equity in the use of clinical preventive services in a health care setting, focusing on three leading causes of death in the United States: cancer, heart disease, and diabetes. Specifically, 10 preventive services for adults will be addressed during the workshop:
Abnormal blood glucose and type 2 diabetes mellitus screening
Aspirin use to prevent cardiovascular disease (CVD) and colorectal cancer: preventive medication
Behavioral counseling to promote healthful diet and physical activity for CVD prevention in adults with cardiovascular risk factors
Breast cancer screening
Cervical cancer screening
Colorectal cancer screening
High blood pressure screening
Lung cancer screening
Obesity screening and management
Tobacco smoking cessation in adults: behavioral and pharmacotherapy interventions. 

Location:  Bethesda, MD, USA

More information:    https://prevention.nih.gov/research-priorities/research-needs-and-gaps/pathways-prevention/achieving-health-equity-preventive-services 

Jun. 19-20, 2019 

2nd Annual UBCO Diabetes Research Day

The BC Diabetes Research Network invites academic faculty and their trainees to the 2nd Annual UBCO Diabetes Research Day. This exciting knowledge exchange event highlights the excellent research being conducted across BC. The meeting is focused on prevention and translational diabetes research. All attendees are invited to submit an abstract to deliver an oral presentation or present a poster. Abstract submission deadline: June 5, 2019.

Location:  Kelowna, BC, Canada

More information:    https://www.diabetesBC.ca 



Funding opportunities information and deadlines in June, 2019

Jun. 1, 2019 

Funding Opportunity Application Due Date: MMPC MICROMouse Program

The MMPC MICROMouse Program is a competitive grants program awarding up to $75,000 (total costs) for one year to fund research projects that have the potential to enhance and advance the mission of the MMPC as a resource for scientists using mice to study diabetes and obesity. Any independent investigator, including post-doctoral fellows, is eligible to apply. A project must be either: 1) resource-development (e.g., develop, improve, miniaturize, teach, distribute, etc. phenotyping tests for use in mice); or 2) resource-related research (e.g., a new, currently unfunded project where results have potential impact for mouse centered research in diabetes or obesity, particularly those focused on broad biological questions that impact the ability of the MMPC to meet its goals). There is no formal deadline associated with MICROMouse applications, but applications will be reviewed quarterly (March 1, June 1, September 1, December 1) and therefore should be submitted accordingly.

More information:    https://www.mmpc.org/shared/microMouse.aspx 


Jun. 3, 2019 

NIDDK Funding Opportunity Application Due Date: Limited Competition: Follow-up on Subjects\, Integrative Data Analysis and Measurement of Viral Antibodies in The Environmental Determinants of Diabetes in The Young Study (TEDDY) (U01 Clinical Trial Not Allowed)

This Funding Opportunity Announcement (FOA) invites one application from the Program Director/Principal Investigator (PD/PI) of the current Data Coordinating Center (DCC) for The Environmental Determinants of Diabetes in the Young (TEDDY) study, an ongoing epidemiological study. This DCC has been involved in study design and data and bio sample acquisition and management since the inception of the TEDDY Consortium. This FOA provides support for the TEDDY DCC to continue to follow TEDDY children and allows funding for collaborators to conduct studies on integration of various "omics" data and the measurement and analysis of viral antibodies using samples from TEDDY subjects.

More information:    https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-18-512.html 

Jun. 3, 2019 

NIDDK Funding Opportunity Application Due Date: HEAL Initiative: Early Phase Pain Investigation Clinical Network - Specialized Clinical Centers (U24 Clinical Trial Not Allowed)

The purpose of this funding opportunity announcement (FOA) is to invite applications for the Specialized Clinical Centers (“hubs”) of the Early Phase Pain Investigation Clinical Network (EPPIC-Net). EPPIC-Net will serve as the cornerstone of the NIH’s Helping to End Addiction Long-term (HEAL) Initiative. EPPIC-Net will provide a robust and readily accessible infrastructure for carrying out in-depth phenotyping and biomarker studies in patients with specific pain conditions, and the rapid design and performance of high-quality Phase 2 clinical trials to test promising novel therapeutics for pain from partners in academia or industry. Studies will bring intense focus to patients with well-defined pain conditions and high unmet therapeutic needs. EPPIC-Net will consist of one Clinical Coordinating Center (CCC), one Data Coordinating Center (DCC) and approximately 10 specialized clinical centers (“hubs”). The purpose of this funding opportunity announcement (FOA) is to invite applications for the hubs within EPPIC-Net. A hub will typically be a regional medical center that will actively enroll subjects into clinical trials and studies performed in EPPIC-Net. Each hub should have ready access to patient populations with specific pain conditions and have expertise in characterization of that pain condition. A hub will additionally provide scientific leadership and administrative oversight to its multiple (2-10) satellite sites (“spokes”). This FOA solicits applications EPPIC-Net Specialized Clinical Centers. Separate FOAs have been issued to solicit applications for the Clinical Coordinating Center (RFA-NS-19-023) and Data Coordinating Center (RFA-NS-19-024). Clinical trials conducted through EPPIC-Net may come from a variety of sources including the HEAL Partnership, as described above, or from separate NIH funding announcements.

More information:    https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-19-036.html 

Jun. 3, 2019 

KPMP (Kidney Precision Medicine Project) Funding Opportunity Application Due Date: Apply for a Glue Grant to partner with the KPMP

This solicitation aims to form new collaborative partnerships by providing “glue grants” to investigators working in areas of high relevance to the KPMP and currently supported by other significant non-KPMP funding sources. Examples of other significant funding sources include, but are not limited to, an NIH R01, RC2, DP3, or U01 award, or a VA MERIT award. Successful glue grants are expected to be mutually beneficial. Applicants should describe how their “parent” project will benefit from being part of the KPMP and how the KPMP will benefit from partnering with the “parent” project. Specifically, glue grant funding will provide a supplement of up to $60,000 total costs per year to the “parent” project to support sharing, harmonization, and integration with the KPMP of relevant data, samples, tissues, reagents, technologies, tools, software, analytic pipelines, expertise, etc.

More information:    https://kpmp.org/wp-content/uploads/2019/03/KPMP-OP-RFA_Glue_Grants_2019-03-26.pdf 

Jun. 05, 2019 

NIDDK Funding Opportunity Application Due Date: Stimulating Urology Interdisciplinary Team Opportunity Research (SUITOR) (R01 Clinical Trial Optional)

The Stimulating Urology Interdisciplinary Team Opportunity Research (SUITOR) program is intended to promote innovative, high quality, interdisciplinary research relevant to the mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The NIDDK invites investigator-initiated research project grant applications (R01s) in specific areas of basic, translational and clinical research in specific benign urologic conditions and diseases where needs and opportunities for progress are particularly timely. Specific research topic areas supported by the SUITOR program, as outlined below, will change over time and will be updated annually through the NIH Guide to Grants and Contracts.

More information:    https://grants.nih.gov/grants/guide/pa-files/PAS-19-241.html 

Jun. 10, 2019 

Funding Opportunity Application Due Date: The 2019 DiaComp Pilot & Feasibility Program

This program solicits and funds small Pilot and Feasibility (P&F) projects in high-impact areas of diabetic complications research that fall within the primary mission of the NIDDK (please see the NIDDK website for full details). Diabetic complications of interest to the NIDDK include diabetic nephropathy, uropathy, neuropathy, neurocognition, gastrointestinal, liver, bone, and wound healing. Applications focused on all other diabetic complications (including diabetic retinopathy and cardiovascular disease) do NOT fall within the primary mission of the NIDDK and will be deemed non-responsive. If an application proposes to study the interconnectivity of multiple diabetic complications, a majority of the proposal must address an NIDDK complication of primary interest. This program aims to support discovery (hypothesis generating) and innovative (high-risk/high-reward) research that will advance our understanding of diabetic complications and that are increasingly difficult to support through standard NIH mechanisms. Basic, translational and clinical research proposals are encouraged. When appropriate, the use of human samples is strongly encouraged. Research involving human subjects is limited to observational studies with non-invasive or minimally invasive testing and must have IRB approval that includes the collection and use of human samples for research purposes. Clinical trials, as defined by the NIH, are beyond the scope of this program. For further details and resources to help clarify the NIH definition, please consult information posted at the NIH Clinical Trials website (https://grants.nih.gov/policy/clinical-trials/definition.htm). Diabetic complications manifest themselves differently between men and women. Understanding the molecular underpinnings of these manifestations is critical to designing tailored therapeutic approaches.Awards are expected to prepare the applicant(s) to submit a future investigator-initiated project (e.g. NIH R01). Lower priority will be given to applicants who have received DiaComp support in the past three years. Foreign applications are NOT allowed.

More information:    https://www.diacomp.org/shared/pilotFeasibility.aspx 

Jun. 10, 2019 

Funding Opportunity Application Due Date: The 2019 DiaComp Conference Support Program

This program supports high-quality scientific conferences that feature sessions or speakers directly relevant to diabetic complications and that promote communication and collaboration between research communities investigating similar pathologic mechanisms in different end organs of complications. Strong proposals will also inform investigative communities that have not traditionally been involved in complications research.

More information:    https://www.diacomp.org/shared/conferenceSupport.aspx 


Jun. 18, 2019 

NIDDK Funding Opportunity Letter of Intent Due Date: Cystic Fibrosis Research and Translation Centers (P30 Clinical Trial Optional)

This Funding Opportunity Announcement (FOA) invites applications for Cystic Fibrosis (CF) Research and Translation Core Centers. CF Research and Translation Core Centers are designed to support both basic and clinical research on Cystic Fibrosis. CF Research and Translation Core Centers support three primary research-related activities: Research Core services; a Pilot and Feasibility program; and an Administrative Core with an enrichment program. Core Centers provide shared resources to support research to develop and test new therapies for CF and to foster collaborations among institutions with a strong existing research base in CF. The NIDDK currently supports seven CF Research and Translation Centers located at institutions with documented programs of research excellence in basic and clinical CF Research. Information about the currently funded CF Research and Translation Centers may be found at:https://www.niddk.nih.gov/research-funding/research-programs/cystic-fibrosis-research-translation-centers or https://www.cysticfibrosiscenters.org/

More information:    https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-19-003.html 


Jun. 20, 2019 

NIDDK Funding Opportunity Application Due Date: Diabetes Research Centers (P30 Clinical Trial Optional)

This Funding Opportunity Announcement (FOA) invites applications for Diabetes Research Centers that are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. Diabetes Research Centers support two primary research-related activities: Research Core services and a Pilot and Feasibility (P and F) program. All activities pursued by Diabetes Research Centers are designed to enhance the efficiency, productivity, effectiveness, and multidisciplinary nature of research in Diabetes Research Center topic areas. The NIDDK Diabetes Research Centers program in 2018 consists of 16 Centers each located at outstanding research institutions with documented programs of excellence in diabetes-related research. General information about the NIDDK Diabetes Research Centers program may be found at www.diabetescenters.org.

More information:    https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-18-020.html 


Jun. 28, 2019 

KPMP(Kidney Precision Medicine Project) Funding Opportunity Application Due Date: Develop kidney biomimetic “phantoms” as quality control standards

This solicitation aims to form new collaborative partnerships by providing KPMP opportunity pool funds to applicants proposing to design, fabricate, characterize, produce, and distribute novel biomimetic phantoms. Ideally, the phantoms will perform several diverse tasks including, but not limited to: (1) Tissue processing and Pre-analytic control. A highly sensitive indicator that can accurately monitor changes (either directly or indirectly) over time to tissue ischemia, hypoxia, analyte degradation, etc. (analogous to a tracking device that can monitor temperature changes of a shipped package). (2) Analytic control. A highly stable positive control with reproducible signal integrity over time of appropriate reference transcripts, proteins, metabolites, cells, structures, etc. (analogous to molecular weight markers used for quantitative and qualitative comparisons).

More information:    https://kpmp.org/wp-content/uploads/2019/03/KPMP-OP-RFA_Phantom_Tissue_2019-03-26.pdf 

Jun. 28, 2019 

KPMP(Kidney Precision Medicine Project) Funding Opportunity Application Due Date: Obtain healthy reference tissue to help build the KPMP kidney tissue atlas

There is a critical need to obtain human healthy reference tissue, including but not limited to, tissue from healthy living donors or healthy volunteers to develop the KPMP kidney tissue atlas. This solicitation aims to form new collaborative partnerships by providing KPMP opportunity pool funds to applicants proposing to ethically and safely obtain, share, and harmonize human healthy reference kidney tissue with the KPMP. Strong applications will provide non-degraded (“pristine”) tissue with the necessary diversity (sex, age, race, and ethnicity) and metadata (including relevant longitudinal clinical data) to meet the objectives of the KPMP. Ideally, it is expected that applicants will employ current KPMP protocols to obtain, share, and harmonize (using associated metadata) at least 20 healthy reference tissue samples per year. Deceased donor and tumor nephrectomy tissue are not eligible for this funding opportunity.

More information:    https://kpmp.org/wp-content/uploads/2019/03/KPMP-OP-RFA_Healthy_ReferenceTissue_2019-03-22.pdf


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