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dkNET community events and announcements in September, 2018

dkNET community events and announcements in September, 2018

Dear dkNET Community,

dkNET provides updates on activities of interest to the NIDDK-supported community. You could keep up to date on these activities through our Twitter feed @dkNET_info, through our Community Calendar, or through dkNET e-mail list. If you have an event or funding opportunities you'd like to advertise, please contact us info_at_dknet.org.

dkNET Updates

  • New resources added to dkNET
Diabetes Genome Atlas (RRID: SCR_016441) collects and provides data on the human genome and epigenome to facilitate genetic studies of type 2 diabetes and its complications. A component of the AMP T2D consortium, which includes the National Institute for Diabetes and Digestive and Kidney Diseases (NIDDK) and an international collaboration of researchers.

Events in September, 2018

Sep. 4-7, 2018

International Conference on the Bioscience of Lipids

Lipid Fluxes and Metabolism –From Fundamental Mechanisms to Human Disease
Preliminary Main Topics:
  • Lipid-induced modulation of protein function
  • Inter-organelle lipid trafficking
  • Regulation of lipid synthesis, catabolism and storage
  • Novel lipid probes for studying lipid transport and metabolism
  • Lipids in inflammation
  • Lipids as markers for health and disease

Location: Helsinki, Finland

Sep. 6-7, 2018 

Islets Society Meeting 2018 

Vanderbilt Diabetes Research and Training Center

Location: Nashville, TN, USA

More information: http://www.isletsociety2018.com/

Sep. 13-14, 2018

NIDDK New Principal Investigator Workshop 

The purpose of this meeting is to provide our first-time R01 investigators with the information they will need to be successful in securing continued support for their research programs at a very critical juncture in their career. It will also provide a networking forum for the new investigators to interact with NIDDK program and review staff and with each other.

Location: Rockville, MD, USA

    More information:  https://www.niddk.nih.gov/news/meetings-workshops/2018/new-pi-workshop-2018

    Sep. 16-19, 2018 

    16th Euro Fed Lipid Congress and Expo

    The Lipids Group of the SCI will host the 2018 Euro Fed Lipid Congress and Expo in Belfast, Northern Ireland. The theme of the meeting in Belfast will be the application of science, technology and nutrition to address the issues arising in our constantly changing world. As well as the usual Euro Fed Lipid Division streams, we will include a stream focussed on dairy fats, since this represents a large industry in Ireland.

    Location: Belfast, UK

    More information: https://veranstaltungen.gdch.de/tms/frontend/index.cfm?l=7660&sp_id=2

    Sep. 20-21, 2018 

    NIDDK Workshop: Autonomic Nervous System: Role in the Regulation of Peripheral Metabolism and Pathophysiology of Metabolic Disease 


    • Increase attendees’ foundational knowledge of the role of the ANS in peripheral metabolism and metabolic disease.
    • Foster interaction between basic and clinical scientists with expertise in metabolism and neuroscience. 
    • Discuss the limitations of technologies/methodologies for measurement of tissue-specific activity and function in humans.
    • Build on the Common Fund–supported program “Stimulating Peripheral Activity to Relieve Conditions” to expand the focus to metabolic disease.
    • Identify research gaps in basic and clinical science.

    Location: Rockville, MD, USA

    More information: https://www.niddk.nih.gov/news/meetings-workshops/2018/autonomic-nervous-system

    Sep. 24-28, 2018 

    11th Annual Course : Presented by the Vanderbilt-NIDDK Mouse Metabolic Phenotyping Center (MMPC), Nashville, Tennessee Glucose Clamping The Conscious Mouse: A Laboratory Course

    A week-long course to familiarize participants with methods, protocols and quantitative tools necessary to perform glucose clamps in the conscious mouse

    Location: Nashville, TN, USA

    More information:  https://mmpc.org/shared/courses.aspx

    Sep. 26-29, 2018 

    7th European Lipidomics Meeting 

    Location: Leipzig, Germany

    More information: https://home.uni-leipzig.de/ELM2018

    Sep. 26-27, 2018 

    NIH Workshop on Biomarkers of Dietary Intake and Exposure: Exploration with Omics Approaches

    The main objective of the current workshop is to engage nutrition and omics researchers in a 2-day workshop and explore the potential of omics approaches for nutritional biomarker research. Recommendations from the workshop will be communicated to the research community and may form the basis for future research initiatives.

    Location: North Bethesda, MD, USA

    More information: https://www.niddk.nih.gov/news/meetings-workshops/2018/workshop-biomarkers-dietary-intake-exposure

    Sep. 27, 2018 

    Endocrine Society FLARE Program application deadline 

    The Future Leaders Advancing Research in Endocrinology (FLARE)program is for basic science, clinical research trainees, and junior faculty from underrepresented minority communities who have demonstrated achievement in endocrine research. FLARE program components provide structured leadership development and in-depth, hands-on training in topics ranging from grantsmanship to lab management. This program is sponsored by a grant from the National Institute of Diabetes and Digestive and Kidney Diseases.

    More information: https://www.endocrine.org/training-and-education/flare

    Funding opportunities information and deadlines in September, 2018

    Sep. 1, 2018 

    Funding Opportunity Letter of Intent Due Date: Biomarker proposal at NIDDK Workshop for Biomarkers for the Diabetic Foot Consortium (DFC)

    Diabetic foot ulcers (DFU) are a common complication of diabetes and lead to about 100,000 lower extremity amputations per year in the United States. Treatment of a DFU is costly, protracted and for many individuals, ineffective. The development of new therapies for diabetic wound healing is fraught with challenges, one of which is the lack of biomarkers to predict healing. The goal of the Diabetic Foot Consortium (DFC) is to validate biomarkers for DFUs through a network of clinical and biomarker measurement sites. The purpose of this workshop is to solicit biomarker proposals that could be studied in the DFC.

    More information: https://grants.nih.gov/grants/guide/notice-files/NOT-DK-18-017.html

    Sep. 3, 2018 

    Funding Opportunity Application Deadline: MMPC Mouse Microbiome Metabolic Research Program (MMMRP)


    The mission of MMPC’s Mouse Metabolic Research Program is to support the development and application of mouse phenotyping technologies to advance microbiome-related research. A clear rationale for how/why the microbiome, such as gut microbiome, lung microbiome, etc, might be expected to impact metabolic phenotyping endpoints in mice must be provided in each proposal. Although there is no requirement for direct collaboration with an MMPC, expected project outcomes should have the potential to add value to the MMPC program. The Mouse Microbiome Metabolic Research Program (MMMRP) is a competitive grants up to $125,000 (total costs) for one year. The program supports for pilot and feasibility projects that incorporate microbiome research into mouse metabolic phenotyping studies. All studies should demonstrate clear potential to advance the mission of the MMPC (www.mmpc.org). Any independent investigator or post-doctoral fellow at a US institution is eligible to apply.

    More information: https://www.mmpc.org/shared/mmmrp.aspx

    Sep. 4, 2018 

    Funding Opportunity Application Deadline: Stanford University Diabetes Research Center Pilot And Feasibility Program 

    The Diabetes Research Center (Stanford DRC) is soliciting new Pilot and Feasibility Projects. The focus of the Stanford DRC Pilot and Feasibility Program is to provide seed funds to help develop new investigators as well as support innovative and/or high-risk proposals from more senior investigators involved in any aspect of diabetes related research, including but not limited to basic sciences, economics, population sciences, translational research and clinical research.

    Sep. 12, 2018 

    JDRF Funding Opportunity Letter of Intend Due Date: Innovative Strategies To Demonstrate “Immunological Proof-of-Mechanism” And To Explore Early Outcome Measures In Immunotherapy Trials

    Letters of intent are sought from investigators/groups that will address any or all of the following: 1) Define a measure or measures that will allow evaluation of candidate immune therapies for treatment effect, in a shorter timescale and with fewer subjects than current practice. 2) Explore early outcome measures that are surrogates for clinical efficacy in immunotherapy trials. 3) Define a lower burden outcome measure that may be frequently sampled with easier tools and technologies than currently available. 4) Define a measure/score for therapeutic effect, incorporating measures that represent early alterations in disease course after interventions.5) Other novel approaches to determine early readouts of immune therapeutic effect and/or link such to improved, earlier outcomes in T1D immunotherapy trials. Examples of pertinent topics include, but are not limited to: -Small prospective intervention trials designed to collect and link mechanistic, metabolic and patient outcome data for exploration of early endpoints after treatment with immunotherapies. -Evaluation of the impact of immunotherapies (if any) on early features of beta cell function that go beyond overall stimulated C-peptide secretion (e.g. early phase insulin secretion, rapid control of post-prandial glucose excursions, appropriate counter-regulation to avoid hypoglycemia, etc.)-Evaluation of datasets from relevant non-immune intervention trials to generate early surrogates of positive metabolic effectsthat can be tested/incorporated in future immune intervention trials. -Validation studies of novel scores or measures of clinical benefit in new data sets, trials or cohorts. -Standardization and harmonization of definitions of responders in immunotherapy trials and for achieving comparable surrogate measures of treatment effect across future trials.


    More information: https://dknet.org/about/dknetnews/1141


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