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dkNET community events and announcements in July, 2018

dkNET community events and announcements in July, 2018

Dear dkNET Community,

dkNET provides updates on activities of interest to the NIDDK-supported community. You could keep up to date on these activities through our Twitter feed @dkNET_info, through our Community Calendar, or through dkNET e-mail list. If you have an event or funding opportunities you'd like to advertise, please contact us info_at_dknet.org.

dkNET Updates

  • New resources added to dkNET
The Pancreatic Beta-Cell Consortium (RRID:SCR_016328) is a portal to provide a repository for beta-cell data, to connect researchers from different backgrounds interested in contributing data, models and/or ideas for new insights into beta-cell biology. Used to understand beta-cell biology and diabetes through a cross-disciplinary approach for the assembly of spatiotemporal multi-scale whole cell models of human pancreatic beta-cells.

BioJupies (RRID:SCR_016346) is an open source web server to automatically generate RNA-seq data analysis of jupyter notebooks. It allows to create and contain documents that have live code, visualisations and narrative text, and can be used to produce a customized, reusable, and interactive report from raw or processed RNA-seq data through a user interface. 

eXpression2Kinases (RRID:SCR_016307) is an open source software application to produce inferred networks of transcription factors, proteins, and kinases predicted to regulate the expression of the inputted gene list by combining transcription factor enrichment analysis, protein-protein interaction network expansion, with kinase enrichment analysis. It provides the results as tables and interactive vector graphic figures.

EPIMHC (RRID:SCR_016279) is a database of naturally processed MHC-restricted peptide ligands and epitopes for customized computational vaccinology. 

Events in July, 2018

July 6-10, 2018

26th Conference on Intelligent System for Molecular Biology

ISMB 2018 provides an intense multidisciplinary forum for disseminating the latest developments in bioinformatics/computational biology, fostering fresh dialogues and perspectives to learn about and shape the future of the field. With intensified community involvement form the ISCB Communities of Special Interest (COSIs), ISMB is the leading conference in the field, with the strongest scientific and technical program that showcases the best international developments in bioinformatics and computational biology.

Location: Chicago, IL, USA

More information: https://www.iscb.org/ismb2018

July 11-12, 2018

19th Annual Harvard Nutrition and Obesity Symposium 

Location: Boston, MA, USA

More information: http://norccentral.org/2018/01/19th-annual-harvard-nutrition-and-obesity-symposium/

July 11, 2018

Workshop Registration Deadline: Accelerating the Drug Delivery Pipeline for Acute and Chronic Pancreatitis: Research Gaps and Opportunities 

Meeting Objectives: (1) To identify the requirements, obstacles and opportunities to enhance the development and clinical testing of potential therapeutic agents for the treatment of acute pancreatitis, recurrent acute pancreatitis and chronic pancreatitis (2) To identify research gaps which are needed to facilitate drug development and clinical testing (3) To engage representatives from the Food and Drug Administration to assist with the development of guidance documents which will assist investigators in studies of the treatment of these diseases. The meeting will be held on July 25, 2018
Location: Pittsburgh, PA, USA

More information:   https://www.niddk.nih.gov/news/meetings-workshops/2018/accelerating-drug-delivery-pipeline-pancreatitis

July 12-13, 2018

NIDDK Renal Imaging Workshop 

The objective of this workshop is to chart a path forward to functional renal imaging. We plan to cover the state of the art in renal imaging and learn from other fields. Toward future clinical use, we will also hear about FDA qualification of imaging biomarkers and other translational challenges. 

Location: Bethesda, MD, USA 

More information:  https://www.niddk.nih.gov/news/meetings-workshops/2018/renal-imaging-workshop

July 15, 2018

Abstract Submission Deadline: European Association of Urology 18th Central European Meeting (CEM18) 

Hosted by the Romanian Association of Urology, the day-long meeting will be preceded by a four-hour session of Live Surgery on 11 October. A compact Scientific Programme will deliver key updates in several urological issues such as andrology and onco-urology, while poster sessions will cover key topics in major areas ranging.

Location: Cluj-Napoca, Romania

More information:  https://cem.uroweb.org/

July 22 - 27, 2018 

6th Annual Workshop on Metabolomics at University of Alabama at Birmingham 

The themes in this sixth year of the workshop are:

  1. Design of a metabolomics experiment
  2. Sample stability and extraction methods
  3. Analytical systems (nuclear magnetic resonance and gas- and liquid chromatography-mass spectrometry)
    1. Targeted metabolomics
    2. Untargeted metabolomics
    3. Quantitative metabolomics
  4. Pre-processing of analytical data (Mzmine 2 and XCMSonline and Chenomx)
  5. Statistical analysis of the data (MetaboAnalyst, Simca, SAS)
  6. Metabolite databases (METLIN, HMDB, LIPIDMAPS, PubChem, ChemSpider)
  7. Identification of metabolites (MetaboSearch, MSMS analysis)
  8. Metabolite pathway analysis (Mummichog, KEGG, GeneGo, Ingenuity)
  9. Advanced elective sessions (Imaging mass spectrometry, isotope ratio outlier analysis, Ion mobility, Command line and R programs)
  10. Electives will allow attendees to fine tune their training experience

Location: Birmingham, AL, USA 

More information:   https://www.uab.edu/proteomics/metabolomics/workshop/workshop_july_2018.php#tab_tab1

July 25, 2018

Workshop Registration Deadline: KUH Undergraduate Summer Research Conference 2018 

This meeting is the culminating experience for the undergraduate participants sponsored by the Division of Kidney, Urologic, and Hematologic Diseases Summer Research Program. The conference will bring all of the students together to share their research accomplishments, network with peers and distinguished faculty, and receive timely career development advice. This added exposure to professional and scientific opportunities in renal, urologic, and hematologic diseases will entice undergraduates to continue their medical or graduate careers in areas within the research mission of the Division. Meeting dates: Aug. 1-3, 2018.

Location: Boston, MA, USA 

More information:  https://www.niddk.nih.gov/news/meetings-workshops/2018/kuh-undergraduate-2018

Funding opportunities information and deadlines in July, 2018

July 2, 2018 

Funding Opportunity Application Due Date: American Diabetes Association Pathway to Stop Diabetes

Pathway to Stop Diabetes is a bold, innovative initiative designed to radically transform diabetes research. Our Vision is simple yet revolutionary: find a new generation of brilliant scientists at the peak of their creativity, and provide them with freedom, autonomy, and the financial and professional resources to set them on the road to breakthrough discoveries. This initiative enables scientists to advance not only their research, but also their careers. Pathway scientists have access to the Mentor Advisory Group, an annual Pathway symposia, select speaking opportunities, and innovative technologies, all designed to foster interactions and collaboration that will enable them to accelerate their research progress.The prestigious Pathway awards are available by institutional nomination only. The 2018 Call for Applications is open. All applications are to be submitted by 5pm ET on July 2, 2018 for January 1, 2019 funding. Each institution is allowed a maximum of one nomination per grant cycle. The nomination can be for any one of the Pathway Program Award types: Initiator, Accelerator or Visionary. Please review all application and nomination materials, as they will be used or referred to during the application submission process.

More information: https://professional.diabetes.org/meetings/pathway-stop-diabetes®

July 9, 2018 

NIH Common Fund Funding Opportunity Application Due Date: Cutting Edge Informatics Tools for Illuminating the Druggable Genome (U01 Clinical Trial Not Allowed) 


The overarching goal of this FOA is to add informatics capabilities to the Common Fund program, Illuminating the Druggable Genome IDG; https://commonfund.nih.gov/idg/. The IDG consortium's purpose is to facilitate the unveiling of the functions of selected understudied proteins in the Druggable Genome using experimental and informatics approaches. Currently, this research consortium is composed of multiple Data and Resource Generation Centers (DRGCs), a Knowledge Management Center (KMC), and a Resource Dissemination and Outreach Center (RDOC). The purpose of this specific FOA is to solicit applications to build a set of Cutting Edge Informatics Tools (CEITs) that will augment the capability of the KMC as well as the broader IDG Consortium in the following ways: (1) by developing and deploying tools to enhance the community's ability to process, analyze, and visualize IDG data, (2) to prioritize new data resources and methods to be incorporated into Pharos https://pharos.nih.gov/idg/index that will strengthen predictions about physiological and disease associations around the understudied proteins, and (3) by developing methods to prioritize understudied IDG families (non-olfactory GPCRs, protein kinases, and ion channels) for deeper study using experimental assays both within the IDG pipeline or by the larger community.

More information: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-18-011.html

July 10, 2018 

NIDDK Funding Opportunity Application Due Date: Elucidating the Effect of Glycemic Excursions on Patient Well-being and Cognitive Status in People with Type 1 Diabetes (T1D) (R01 Clinical Trial Optional) 

This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing research on the use of current and emerging technologies for monitoring of blood glucose levels to capture the relationship between blood glucose excursions, perception of wellbeing, and cognitive status in people with type 1 diabetes (T1D).  This information will inform the design of more effective interventions that may improve patient reported outcomes (PROs), including quality of life measures, and validate glycemic measures that may serve as outcomes in clinical trials to improve glucose management in T1D.

July 10, 2018 

NIDDK Funding Opportunity Application Due Date: Funding For Collaborative Clinical Research In Type 1 Diabetes: Living Biobank (R01 Clinical Trial Optional)

This Funding Opportunity Announcement (FOA) invites applications for studies of etiology and pathogenesis related to development of type 1 diabetes (T1D) and/or its complications. Studies must involve subjects enrolled and followed in clinical trials, long term follow-up, or observational studies. This opportunity is intended to fund collaborative projects that bring new expertise and innovative approaches to enhance the value of major ongoing clinical research projects.

July 10, 2018 

NIDDK Funding Opportunity Application Due Date: Incorporating Patient-Reported Outcomes into Clinical Care for Type 1 Diabetes (R01 Clinical Trial Required) 

This FOA will support research to test approaches in the healthcare setting to using Patient-Reported Outcomes (PROs) as tools to enhance patient-centered treatment and improve outcomes in individuals with type 1 diabetes.

July 10, 2018 

NIDDK Funding Opportunity Application Due Date: Mass Spectrometric Assays for the Reliable and Reproducible Detection of Proteins/Peptides of Importance in Type 1 Diabetes Research (U01 Clinical Trial Not Allowed) 

This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing the development of targeted mass spectrometric assays (e.g. Multiple Reaction Monitoring) for proteins and peptides of primary interest to the type 1 diabetes research community (e.g. glucagon, somatostatin, C-peptide, insulin, and Glycated CD59).  The proposed assays should be highly reproducible, easily transferable to other laboratories, easy to multiplex, and validated in human plasma or serum.

July 10, 2018 

NIDDK Funding Opportunity Application Due Date: Treating Diabetes Distress to Improve Glycemic Outcomes in Type 1 Diabetes (R01 Clinical Trial Required) 

This FOA seeks applications for clinical trials testing interventions targeting diabetes distress in individuals with T1D and/or their caregivers, with the goal of understanding whether lowering diabetes distress will improve glycemic control and quality of life.

July 16, 2018 

Funding Opportunity Application Due Date: Washington University In St. Louis Diabetes Research Center Pilot And Feasibility Grant Program

The Washington University Diabetes Research Center anticipates awarding new Pilot & Feasibility Grants starting 12/01/18. Funding should support the generation of preliminary data leading to the submission of new applications for independent (NIH, JDRF, or ADA) research grants. Faculty members from any department at Washington University are encouraged to apply. Applicants must hold a faculty appointment and be independent investigators. Postdoctoral Fellows or their equivalent are not eligible.

July 16, 2018 

Funding Opportunity Application Due Date: Diet and Physical Activity Assessment Methodology (R21 Clinical Trial Optional) 

This Funding Opportunity Announcement (FOA) encourages innovative research to enhance the quality of measurements of dietary intake and physical activity. Applications submitted to this FOA may include development of: novel assessment approaches; better methods to evaluate instruments; assessment tools for culturally diverse populations or various age groups, including children and older adults; improved technology or applications of existing technology; statistical methods/modeling to improve assessment and/or to correct for measurement errors or biases; methods to investigate the multidimensionality of diet and physical activity behavior through pattern analysis; or integrated measurement of diet and physical activity along with the environmental context of such behaviors.

July 23, 2018 

Funding Opportunity Letter of Intent Due Date: Boston Nutrition Obesity Research Center Pilot And Feasibility Program 

The mission of the NIDDK-funded Boston Nutrition Obesity Research Center (BNORC) is to facilitate and support the conduct of cutting edge basic and translational research in the fields of nutrition and obesity science in the Boston area. BNORC’s Pilot and Feasibility Program provides funding on a competitive basis for new investigators who are transitioning to an independent line of research or established investigators with novel ideas in the area of nutrition and obesity research. Applications that address the themes of the Center will be given higher priority. These themes are: Nutrient Metabolism in Health and Disease, Brain Control of Feeding Behavior and Metabolism, Environmental and Genetic Influences on Obesity and Related Chronic Diseases.


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