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dkNET community events and announcements in May, 2018

Dear dkNET Community,

dkNET provides updates on activities of interest to the NIDDK-supported community. You could keep up to date on these activities through our Twitter feed @dkNET_info, through our Community Calendar, or through dkNET e-mail list. If you have an event or funding opportunities you'd like to advertise, please contact us info_at_dknet.org.


dkNET Updates:

  • New resources added to dkNET
International Institute for the Advancement of Medicine (RRID:SCR_016172) is a biomaterial supplier that links organ and tissue donors with the scientific community. After securing the appropriate consent, IIAM provides non-transplantable organs and tissues to researchers for use in medical discovery and education

Datasets2Tools (RRID:SCR_016174) is a database for the discovery and evaluation of biomedical digital objects. It includes a wide variety of enrichment analyses, gene interaction networks, interactive data visualizations, datasets, and computational tools.


Direct Infusion Metabolite Database (RRID:SCR_016188) is a database of metabolite structures and annotations. The sources are from multiple existing metabolic and chemical databases such as HMDB, PubChem, CHEBI, BioCyc, and KEGG.


Events in May, 2018

May 1, 2018

Abstract Submission Deadline: ObesityWeek

The Obesity Society’s Annual Scientific Meeting has grown to be one of the world’s largest gatherings of obesity professionals at all stages of their careers, including leading obesity scientists presenting cutting-edge research. The meeting brings together the leading players in the field of obesity from world-renowned speakers, researchers and clinicians to educators, advocates, policymakers and practitioners. And, it provides essential educational and networking opportunities and is a forum for increasing knowledge, stimulating research, and promoting better treatment for those affected by this disease.

Location: Nashville, TN, USA 

More information: http://www.obesity.org/meetings/obesity-week


May 4, 2018

Abstract submission deadline: 2nd International Symposium on Lipid Oxidation and Antioxidants 

This meeting will be a great opportunity to discuss theoretical aspects of lipid oxidation as well as state-of-the-art knowledge and applications in lipid oxidation prevention. Discussions will take place on scientific and technological developments in lipid oxidation and antioxidants in six sessions covering - antioxidant and lipid oxidation evaluation methods - elucidation of lipid oxidation and antioxidant mechanisms - lipid oxidation in multiphase and complex systems - control of lipid oxidation - protein and lipid co-oxidation and - nutritional and physiological effects of oxidized lipids and antioxidants.

Location: Graz, Austria 

May 4, 2018

Workshop Application Deadline: 6th Annual Workshop on Metabolomics at University of Alabama at Birmingham The themes in this sixth year of the workshop are:

  1. Design of a metabolomics experiment
  2. Sample stability and extraction methods
  3. Analytical systems (nuclear magnetic resonance and gas- and liquid chromatography-mass spectrometry)
    1. Targeted metabolomics
    2. Untargeted metabolomics
    3. Quantitative metabolomics
  4. Pre-processing of analytical data (Mzmine 2 and XCMSonline and Chenomx)
  5. Statistical analysis of the data (MetaboAnalyst, Simca, SAS)
  6. Metabolite databases (METLIN, HMDB, LIPIDMAPS, PubChem, ChemSpider)
  7. Identification of metabolites (MetaboSearch, MSMS analysis)
  8. Metabolite pathway analysis (Mummichog, KEGG, GeneGo, Ingenuity)
  9. Advanced elective sessions (Imaging mass spectrometry, isotope ratio outlier analysis, Ion mobility, Command line and R programs)
  10. Electives will allow attendees to fine tune their training experience

Location: Birmingham, AL, USA

More information: https://www.uab.edu/proteomics/metabolomics/workshop/workshop_july_2018.php#tab_tab1


May 22-23, 2018

Workshop Registration Deadline: Obesity and Fat Metabolism in HIV Infected Individuals

Meeting Objectives:

  • An Action Plan with specific recommendations for future obesity research in HIV
  • Identification of research gaps, needs, opportunities, and plans to facilitate progress and catalyze new research directions.
  • Knowledge exchange and the development of further collaborations and joint collaborations to advance the field.
Registration deadline: May 14, 2018

Location: Rockville, MD, USA

More information:  https://www.niddk.nih.gov/news/meetings-workshops/2018/obesity-and-fat-metabolism-in-hiv-infected-individuals

May 23, 2018

Abstract Submission Deadline: 88th Annual Meeting of the American Thyroid Association

Join over 1,300 THYROID clinicians, investigators and healthcare professionals from around the world to hear the latest clinical and basic science research on thyroid disease at the 88th Annual Meeting of the American Thyroid Association (ATA) on October 3-7, 2018. The ATA Program Committee led by Gregory Randolph and Mabel Ryder will offer a program consistent with the excellence for which the ATA is known. The ATA meeting is designed for the community of endocrinologists, basic scientists, internists, surgeons, nuclear medicine scientists, pathologists, trainees, nurses, physician assistants, advanced practice providers and other health care professionals who wish to broaden and update their knowledge of the thyroid gland and its disorders. A customized educational track will be available to trainees to enhance their meeting experience.

Location: Washington DC, USA 

More information:  https://www.thyroid.org/88th-annual-meeting-ata/
 


May 29, 2018

Workshop Registration Deadline: Beyond Transcriptomics: Understanding Erythrocyte Maturation 

Prior to nuclear extrusion from pronormoblasts, critical pathways are developed and continue functioning to ensure optimal erythrocyte function. Knowledge about individual gene products does not necessarily inform us about pathways/processes and their interactions. The purpose of this workshop is to explore these processes and to discuss metabolic reprogramming, proteostasis, integration of transcriptomics, proteomics and other -omics, and enucleation. Please join us in an open forum to discuss the state of the field and to identify gaps in our knowledge. Registration deadline: May 21, 2018.

Location: Bethesda, MDUSA 

More information:  https://www.niddk.nih.gov/news/meetings-workshops/2018/beyond-transcriptomics-understanding-erythrocyte-maturation

May 31 - June 1, 2018

NIDDK Workshop: Congenital Anomalies of External Genitalia Workshop 

The Congenital Anomalies of External Genitalia Workshop will be held on May 31st and June 1st, 2018 at the AUA Headquarters in Linthicum, MD. This two-day meeting will bring together researchers from a range of disciplines, including pediatric urology, developmental biology, genetics & genomics, computational biology, endocrinology, and epidemiology, with the goal of advancing basic and clinical research in hypospadias and related disorders of external genital development. Presentations and roundtable discussions of current research strategies will aim to identify key knowledge gaps and missed opportunities, and to develop potential investigative solutions that will address deficiencies in the field. Basic and clinical researchers interested in the causes of hypospadias and related congenital anomalies of external genitalia are encouraged to attend.

Location: Linthicum Heights, MD, USA

More information:  https://www.niddk.nih.gov/news/meetings-workshops/2018/congenital-anomalies-external-genitalia-workshop


May 31, 2018

Abstract Submission Deadline: Kidney Week 

Join ASN and more than 13,000 other kidney professionals from across the globe at Kidney Week 2018 in San Diego, CA on Oct. 23-28, 2018. The world's premier nephrology meeting, Kidney Week provides participants exciting and challenging opportunities to exchange knowledge, learn the latest scientific and medical advances, and listen to engaging and provocative discussions with leading experts in the field.

Location: San Diego, CA, USA 

More information: https://www.asn-online.org/education/kidneyweek/


Funding opportunities information and deadlines in May, 2018

May. 3, 2018 

Funding Opportunity Application Due Date: Michigan Metabolomic And Obesity Center(MMOC) And Michigan Nutrition And Obesity Research Center (MNORC) Pilot And Feasibility Program  

The purpose of the MNORC Pilot /Feasibility (P/F) Grant Program is to promote research on the biological and behavioral determinants of obesity, and to develop interventions to reduce obesity and its disease sequelae using basic, clinical, or population approaches. The P/F program’s aim is to enable both new and established University of Michigan investigators to generate sufficient preliminary information for a successful application for major research funding from NIH or other national granting agencies. Grant proposals may be in areas of basic biomedical research or in clinical, epidemiological, or translational research, e.g. interventions in clinical or population-based setting. Animal or human models may be considered. Grant proposals involving cross-disciplinary expertise, Faculty from different UM schools, and that utilize the core laboratories of the MNORC are especially encouraged. The MNORC 2017 Call for Proposals aims to foster research addressing key questions in the areas of: Pathogenesis, diagnosis, prevention, or control of obesity; complications of obesity or related endocrine or metabolic disorders (e.g. counter-regulatory proteins, metabolic syndrome); neuro-peptides that may control eating behavior or energy expenditure; adipose tissue biology; influence of gut flora on nutrient absorption and cellular functions related to energy utilization. Translational research projects are encouraged and should focus on research advances into clinical practice or population-based interventions related to obesity, and include identification of barriers to widespread adoption of new science and the testing of interventions to overcome these barriers. Eligibility:  Individuals who have full-time instructional or research faculty positions at the University of Michigan are eligible to apply as Principal Investigators of P/F proposals.

More information: https://umms.infoready4.com/#competitionDetail/1770146


May. 4, 2018 

Funding Opportunity Application Deadline: Nutrition Obesity Research Center, University Of Alabama At Birmingham Pilot And Feasibility Program 

Description:

Pilot/Feasibility Studies provide 1-2 years of support to enable eligible investigators to explore the feasibility of nutrition or obesity-related concept and acquire sufficient data to pursue extramural funding opportunities. Pilot/Feasibility funding generally supports full-time faculty members who are new investigators (usually below the rank of Associate Professor) and without current or past NIH research project support. Less frequently, we fun established investigator for whom the topics of nutrition and obesity represent a substantial departure from their current work. Solicitation of applications occurs annually, with the intent to support 4-5 on-goin Pilot/Feasibility Study projects at a level of up to $25,000/year. Eligibility:  full-time UAB faculty members who are new investigators without current or past NIH research project support (those below the rank of Associate Professor); established investigators with no previous work in nutrition or obesity research; or established investigators in nutrition/obesity with a proposal to test an innovative idea representing a significant departure from ongoing research interests. P/F awards may be made to post-doctoral fellows. However, generally, post-doctoral fellows will only be competitive when such individuals are preparing to transition to a faculty slot at UAB.

More information: http://www.norc.uab.edu/pilot/opportunities



May 4, 2018 

Funding Opportunity Application Due Date: 2018 (Re)Building A Kidney Consortium Partnership Program 

The RBK Partnership Project Program (PPP) invites investigators to submit applications that, if successful, will become part of the RBK (RFA-DK-14-010 & RFA-DK-14-009). The PPP aims to support the goals of the RBK through solicitation of additional projects and/or expertise in specific subject areas. Awardees of the PPP become full members of the RBK. Applications of 5 pages requesting up to $150,000 total cost per year for two years are due May 4, 2018. Current subject areas of interest are LIMITED to Physiologic Function and Repair/Regeneration.



May 8, 2018 

Information Webinar for Applicants to “Funding For Collaborative Clinical Research In Type 1 Diabetes: Living Biobank (R01 Clinical Trial Optional)” 

Webinar to assist applicants to Funding For Collaborative Clinical Research In Type 1 Diabetes: Living Biobank (R01 Clinical Trial Optional).


May 10, 2018 

HIRN RFA Funding Opportunity Application Due Date: Discovery of Early Type 1 Diabetes Disease Biomarkers in the Human Pancreas [HIRN Consortium on Beta Cell Death and Survival (CBDS)] (U01 Clinical Trial Not Allowed) 

This Funding Opportunity Announcement (FOA) requests applications to explore human pancreatic tissues for the discovery of early biomarkers of T1D pathogenesis, the description of specific signaling or processing pathways that may contribute to the asymptomatic phase of T1D, the development of clinical diagnostic tools for the detection and staging of early T1D in at-risk or recently-diagnosed individuals, and/or the identification of therapeutic targets for the development of preventative or early treatment strategies. Successful applicants will join the Consortium on Beta Cell Death and Survival (CBDS), whose mission is to better define and detect the mechanisms of beta cell stress and destruction central to the development of T1D in humans, with the long-term goal of detecting beta cell destruction and protecting the residual beta cell mass in T1D patients as early as possible in the disease process, and of preventing the progression to autoimmunity. The CBDS is part of a collaborative research framework, the Human Islet Research Network (HIRN, https://hirnetwork.org), whose overall mission is to support innovative and collaborative translational research to understand how human beta cells are lost in T1D, and to find innovative strategies to protect and replace functional beta cell mass in humans. This FOA will only support studies with a primary focus on increasing our understanding of human disease biology (as opposed to rodent or other animal models).  This FOA will not accept applications proposing a clinical trial. 

More information: https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-17-021.html


May 10, 2018 

HIRN RFA Funding Opportunity Application Due Date: High-Resolution Exploration of the Human Islet Tissue Environment [HIRN Human Pancreas Analysis Consortium (HPAC)] (U01 Clinical Trial Not Allowed) 

Description:

This Funding Opportunity Announcement (FOA) invites cooperative agreement applications that will contribute to a higher resolution understanding of the physical and functional organization of the human islet tissue environment by describing the composition (cellular and molecular) and function of important components of the pancreatic islet and peri-islet tissue architecture, the cell-cell relationships and means of communications used by cell types and cell subtypes within the pancreatic tissue ecosystem, and/or the contribution of adjacent (including acinar, ductal, lymphatic) and neighboring (intestinal, mesenteric and adipose) tissues to islet cell function and dysfunction. Successful projects will integrate the Human Pancreas Analysis Consortium (HPAC), that will consist of the research teams funded in response to this FOA with the Human Pancreas Analysis Program (HPAP), a resource-generation program that was funded in 2016 in response to RFA-DK-15-027. HPAC will become the fifth consortium of the Human Islet Research Network (HIRN, https://hirnetwork.org/ ). HIRN's overall mission is to support innovative and collaborative translational research to understand how human beta cells are lost in T1D, and to find innovative strategies to protect and replace functional beta cell mass in humans. This FOA will only support studies with a primary focus on increasing our understanding of human tissue structure and function, and human disease biology (as opposed to rodent or other animal models). This FOA will not accept applications proposing a clinical trial. 

More information:  https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-17-022.html


May 10, 2018 

NIDDK Funding Opportunity Application Due Date: Development and Integration of Novel Components for Open and Closed Loop Hormone Replacement Platforms for T1D Therapy (R01 Clinical Trial Optional) 

This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing original research addressing barriers that limit progress toward effective open- and closed-loop glucose control systems.  Proposed research should tackle important obstacles at the level of sensing, hormone formulation and delivery, self-management decision support systems, and/or design of automated controllers/algorithms able to manage an integrated platform. This research may contribute to development of affordable and user friendly technologies to improve glucose control in patients with type 1 diabetes.



May 10, 2018 

NIDDK Funding Opportunity Application Due Date: Development of New Technologies and Bioengineering Solutions for the Advancement of Cell Replacement Therapies for Type 1 Diabetes (T1D) (R01 Clinical Trial Optional) 

This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing original research addressing barriers that limit progress toward effective cell replacement therapies for type 1 diabetes (T1D). The purpose is to support research leading to the development and testing of novel and supportive technologies for the improvement of cell replacement interventions using novel biomaterials and devices for T1D treatment.



May 10, 2018 

NIDDK Funding Opportunity Application Due Date: Immune System Engineering For Targeted Tolerance in Type 1 Diabetes (R01 Clinical Trial Not Allowed) 

Type 1 diabetes (T1D) results in part from the autoimmune-mediated dysfunction or destruction of insulin-producing pancreatic beta cells. This funding opportunity is for projects that seek to discover ways to change the course of the disease by directly establishing tolerance. Immune responses could be engineered for tolerance induction through the manipulation of antigens, cells, or cellular microenvironments. Collaborations between T1D experts and investigators from other fields, including (but not limited to) cancer immunology and biomaterials engineering, are especially encouraged.



May 11, 2018 

Funding Opportunities Application Deadline: Application Deadline: Chicago Center For Diabetes Translation Research Pilot And Feasibility Grants Program 

Chicago Center for Diabetes Translation Research Pilot and Feasibility Grants Program aimed at: 1) Attracting more junior investigators of the faculty into the area of type II diabetes-related translational research; 2) Allowing more established investigators who are not currently engaged in type II diabetes translational research to extend their investigations into this important area; or 3) Permitting any investigator to test a novel hypothesis of relevance to diabetes type II translational research which might not yet meet NIH requirements for R01 or R18 funding. Applicants must be CCDTR members to apply.


May 11, 2018 

Information Webinar for Applicants to “Funding For Collaborative Clinical Research In Type 1 Diabetes: Living Biobank (R01 Clinical Trial Optional)” 

Webinar to assist applicants to Funding For Collaborative Clinical Research In Type 1 Diabetes: Living Biobank (R01 Clinical Trial Optional).


May 31, 2018 

Funding Opportunity Application Due Date: Georgia Center For Diabetes Translation Research: Pilot & Feasibility Pilot Award Program 

Emory University, in partnership with Georgia Tech and Morehouse School of Medicine, has received funding from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to establish the Georgia Center for Diabetes Translation Research (Georgia CDTR). The mission of the center is to facilitate and grow diabetes translation research at Emory, its partner institutions, and regionally. In alignment with this mission, this Request for Pilot and Feasibility Applications is a solicitation for pilot proposals that focus on Type II translation research in diabetes care and prevention. Type II (T2) translation is defined as research focused on translating interventions/approaches that have clearly demonstrated efficacy into real world health care settings, communities, and populations at risk with an emphasis on reach, sustainability, and potential for widespread implementation.Investigators are encouraged to propose studies that align with the focus of one or more Research Cores within the Center:  Disparities, Design and Evaluation, and Engagement and Behavior Change. The Disparities Core addresses the roles of demographic, life-span, race/ethnicity, immigration, and diabetes co-morbidities (e.g., co-existent CVD, HIV or cognitive and psychological disorders) on diabetes rates, treatment, and outcomes. The Design and Evaluation Core focuses on models of delivering effective preventive and health care services, including innovative use of technologies, workforce development, and/or metrics and evaluation. The Engagement and Behavior Change Core focuses on enhancing adoption and maintenance of prevention and care interventions for diabetes among those in need and incorporates expertise and resources from the fields of behavioral sciences, screening, and community-based participatory research. In addition, proposals are encouraged, although not required, to focus on the following target populations: minorities, the elderly, youth, and persons with HIV. Eligibility: Faculty researchers from Emory University, Morehouse School of Medicine, the Atlanta Veterans’ Affairs System, Georgia Institute of Technology and Georgia State University are eligible to apply for pilot and feasibility funding if they fit in one of the following categories: (1) New investigators without current or past NIH research support as a principal investigator or program director (priority) (2)Established investigators with no previous work in T2 translation diabetes research (3)Established investigators who propose testing innovative ideas that represent a clear departure from their ongoing research interests.



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