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Systems Biology Graphical Notation

The Systems Biology Graphical Notation (SBGN) project aims to develop high quality, standard graphical languages for representing biological processes and interactions. Each SBGN language is based on the consensus of the broad international SBGN community of biologists, curators and software developers. Over the course of its development many individuals, organizations and companies made invaluable contributions to the SBGN through participating in discussions and meetings, providing feedback on the documentation and worked examples, adopting the standard and spreading the word. Circuit diagrams and Unified Modeling Language diagrams are just two examples of standard visual languages that help accelerate work by promoting regularity, removing ambiguity and enabling software tool support for communication of complex information. Ironically, despite having one of the highest ratios of graphical to textual information, biology still lacks standard graphical notations. The recent deluge of biological knowledge makes addressing this deficit a pressing concern. Toward this goal, we present the Systems Biology Graphical Notation (SBGN), a visual language developed by a community of biochemists, modelers and computer scientists. SBGN consists of three complementary languages: process diagram, entity relationship diagram and activity flow diagram. Together they enable scientists to represent networks of biochemical interactions in a standard, unambiguous way. We believe that SBGN will foster efficient and accurate representation, visualization, storage, exchange and reuse of information on all kinds of biological knowledge, from gene regulation, to metabolism, to cellular signaling. A list of software packages known to provide (or have started to develop) support for SBGN notations is available.

URL: http://www.sbgn.org/Main_Page

Resource ID: nlx_66628     Resource Type: Resource     Version: Latest Version



Funding Information

New Energy and Industrial Technology Development Organization, Okinawa Institute of Science and Technology, BBSRC, National Institute of Advanced Industrial Science and Technology of Japan, European Media Laboratory EML Research GmbH, California Institute of Technology; California; USA, NIH, 1R01GM081070-01

Additional Resource Types

topical portal, international standard specification, software resource, meeting resource



Original Submitter


Version Status


Submitted On

12:00am July 29, 2011

Originated From


Changes from Previous Version

First Version

Version 1

Created 4 years ago by Anonymous