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Stanford Center for Narcolepsy

The Stanford Center for Narcolepsy was established in the 1980s as part of the Department of Psychiatry and Behavioral Sciences. Today, it is the world leader in narcolepsy research with more than 100 articles on narcolepsy to its name. The Stanford Center for Narcolepsy was the first to report that narcolepsy-cataplexy is caused by hypocretin (orexin) abnormalities in both animal models and humans. Under the direction of Drs. Emmanuel Mignot and Seiji Nishino, the Stanford Center for Narcolepsy today treats several hundred patients with the disorder each year, many of whom participate in various research protocols. Other research protocols are conducted in animal models of narcolespy. We are always looking for volunteers in our narcolepsy research studies. We are presently recruiting narcoleptic patients for genetic studies, drug clinical trials, hypocretin measurement studies in the CSF and functional MRI studies. Monetary gifts to the Center for Narcolepsy are welcome. If you wish to make the ultimate gift, please consider participating in our Brain Donation Program. To advance our understanding of the cause, course, and treatment of narcolepsy, in 2001 Stanford University started a program to obtain human brain tissue for use in narcolepsy research. Donated brains provide an invaluable resource and we have already used previously donated brains to demonstrate that narcolepsy is caused by a lack of a very specific type of cell in the brain, the hypocretin (orexin) neuron. While the brain donations do not directly help the donor, they provide an invaluable resource and a gift to others. The real answers as to what causes or occurrs in the brain when one has narcolepsy will only be definitively understood through the study of brain tissue. Through these precious donations, narcolepsy may eventually be prevented or reversible. We currently are seeking brains from people with narcolepsy (with cataplexy and without), idiopathic hypersomnia and controls or people without a diagnosed sleep disorder of excessive sleepiness. Control brains are quite important to research, as findings must always be compared to tissue of a non-affected person. Friends and loved ones of people who suffer with narcoleps may wish to donate to our program to help fill this very important need. Refer to the Movies tab for movies of Narcolepsy / Cataplexy.

URL: http://med.stanford.edu/school/Psychiatry/narcolepsy/

Resource ID: nlx_144254     Resource Type: Resource     Version: Latest Version


brain tissue, brain, tissue, hypocretin, orexin, narcolepsy, sleep disorder, cataplexy, idiopathic hypersomnia, normal control, kleine-levin syndrome, dog, zebrafish, research, therapy


Sample type: Brain tissue, Brain, Tissue

Listed By

One Mind Biospecimen Bank Listing, Biobank

Related Application



human, non-human animal


Stanford Center for Narcolepsy


Stanford University Center for Narcolepsy

Parent Organization



Funding Information

Individual gifts, NIH,

Additional Resource Types

Topical Portal, Brain Bank, Material Storage Repository, Video Resource


Private: not stated but looks that way

Related Disease

Narcolepsy, Sleep disorder, Cataplexy, Idiopathic hypersomnia, Normal control, Kleine-Levin Syndrome

Original Submitter


Version Status


Submitted On

12:00am March 16, 2012

Originated From


Changes from Previous Version

  • Description was changed
  • Funding Information was changed
  • Additional Resource Types was changed

Version 2

Created 2 weeks ago by Christie Wang

Version 1

Created 3 years ago by Anonymous