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The Protein Information Resource (PIR) is an integrated public bioinformatics resource to support genomic, proteomic and systems biology research and scientific studies. For over four decades the PIR has provided databases and protein sequence analysis tools to the scientific community, including the Protein Sequence Database (PSD), which grew out from the Atlas of Protein Sequence and Structure. Located both at the University of Delaware and Georgetown University, PIR conducts research in biomedical text mining and ontology, computational systems biology, and bioinformatics cyberinfrastructure. The PIR web sites are freely accessible by researchers worldwide with over 4 million hits per month from over 100,000 unique sites. In 2002 PIR, along with its international partners, EBI (European Bioinformatics Institute) and SIB (Swiss Institute of Bioinformatics), were awarded a grant from NIH to create UniProt, a single worldwide database of protein sequence and function, by unifying the PIR-PSD, Swiss-Prot, and TrEMBL databases. Currently, PIR major activities include: i) UniProt (Universal Protein Resource) development, ii) iProClass protein data integration and ID mapping, iii) PRO protein ontology, and iv) iProLINK protein literature mining and ontology development. The FTP site provides free download for iProClass, PIRSF, and PRO

URL: http://proteininformationresource.org/

Resource ID: nif-0000-00143     Resource Type: Resource     Version: Latest Version


annotation, genomic, mining, protein, protein bioinformatics, proteomic, research, sequence, structure, systems biology, gold standard

Curation Status




Resource Status

Last checked up;




Protein Information Resource, PIR - Protein Information Resource, Protein Information Resource

Parent Organization

Funding Information

NLM, P41 LM05798

Additional Resource Types

topical portal, data analysis service, database

Publication Link


Original Submitter


Version Status


Submitted On

12:00am July 14, 2011

Originated From


Changes from Previous Version

First Version

Version 1

Created 4 years ago by Anonymous