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A collaboration involving developers of science-based ontologies who are establishing a set of principles for ontology development with the goal of creating a suite of orthogonal interoperable reference ontologies in the biomedical domain. In addition to a listing of OBO ontologies, this site provides a statement of the OBO Foundry principles, discussion fora, technical infrastructure, and other services to facilitate ontology development. Feedback is welcome and participation encouraged.

URL: http://www.obofoundry.org/

Resource ID: nlx_22892     Resource Type: Resource     Version: Latest Version


biomedical, metadata standard, gold standard

Listed By


Publication Link





OBO Foundry, Open Biological and Biomedical Ontologies, Open Biological and Biomedical Ontology Foundry, The Open Biomedical Ontologies

Parent Organization

Additional Resource Types

Standard Specification, Ontology, Knowledge Environment



Original Submitter


Version Status


Submitted On

12:00am June 30, 2011

Originated From


Changes from Previous Version

  • Description was changed
  • Additional Resource Types was changed

Version 2

Created 2 months ago by Christie Wang

Version 1

Created 4 years ago by Anonymous

The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration.

  • Smith B
  • Nat. Biotechnol.
  • 2007 8

The value of any kind of data is greatly enhanced when it exists in a form that allows it to be integrated with other data. One approach to integration is through the annotation of multiple bodies of data using common controlled vocabularies or 'ontologies'. Unfortunately, the very success of this approach has led to a proliferation of ontologies, which itself creates obstacles to integration. The Open Biomedical Ontologies (OBO) consortium is pursuing a strategy to overcome this problem. Existing OBO ontologies, including the Gene Ontology, are undergoing coordinated reform, and new ontologies are being created on the basis of an evolving set of shared principles governing ontology development. The result is an expanding family of ontologies designed to be interoperable and logically well formed and to incorporate accurate representations of biological reality. We describe this OBO Foundry initiative and provide guidelines for those who might wish to become involved.