Network Ontology Analysis (NOA) (abbreviated to NOA) is a freely available collection of Gene Ontology tools aiming to analyze functions of gene network instead of gene list. Network rewiring facilitates the function changes between conditions even with the same gene list. Therefore, it is necessary to annotate the specific function of networks by considering the fundamental roles of interactions from the viewpoint of systems biology. NOA is such a novel functional enrichment analysis method capable to handle both dynamic and static networks. The application of NOA in biological networks shows that NOA can not only capture changing functions in rewiring networks but also find more relevant and specific functions in traditional static networks.
Platform: Online tool
Resource Type: Resource
Version: Latest Version
gene, ontology, ontology or annotation browser, statistical analysis, term enrichment, browser
National Natural Science Foundation of China, Chinese Academy of Sciences; Beijing; China, NSF Shanghai, 60873205, 10801131, 60970091, kjcs-yw-s7, 2009CSP002, KSCX2-EW-R-01, 61072149, 91029301, 11ZR1443100, 60873205
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