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Mouse Party

Mouse Party is an interactive website that teaches how various drugs disrupt the synapse by taking a look inside the brains of mice on drugs! Every drug of abuse has its own unique molecular mechanism. Where applicable, this presentation primarily depicts how drugs interact with dopamine neurotransmitters because this website focuses on the brain''s reward pathway. Mouse Party is designed to provide a small glimpse into the chemical interactions at the synaptic level that cause the drug user to feel ''high''. The simplified mechanisms of drug action presented here are just a small part of the story. When drugs enter the body they elicit very complex effects in many different regions of the brain. Often they interact with many different types of neurotransmitters and may bind with a variety of receptor types in a variety of different locations. For example, THC in marijuana can bind with cannabinoid receptors located on the presynaptic and/or postsynaptic cell in a synapse.

URL: http://learn.genetics.utah.edu/content/addiction/drugs/mouse.html

Resource ID: nif-0000-00429     Resource Type: Resource     Version: Latest Version


drug of abuse, ecstasy, mdma, excitatory neurotransmitter, gaba, gaba-gated anionic channel, alcohol, anandamide, brain, cannabinoid, cannabinoid receptor, cocaine, dopamine, dopamine receptor, dopamine transporter, glutamate, glutamate receptor, heroin, inhibitory neurotransmitter, locus ceruleus, lsd, marijuana, methamphetamine, neurotransmitter, neurotransmitter receptor, neurotransmitter secretion, neurotransmitter transport, neurotransmitter uptake, reward pathway, serotonin, serotonin receptor, serotonin transport, serotonin transporter, synapse, synaptic cleft, tetrahydrocannabinol


Mouse Party

Additional Resource Types

Training Material, Video Resource



Parent Organization

Original Submitter


Version Status


Submitted On

12:00am September 21, 2010

Originated From


Changes from Previous Version

  • Description was changed
  • Additional Resource Types was changed

Version 2

Created 2 months ago by Christie Wang

Version 1

Created 5 years ago by Anonymous