Integrated databases and bioinformatics tools to support genomic, proteomic and systems biology research.
PIR maintains the Protein Sequence Database (PSD), an annotated protein database containing over 283 000 sequences covering the entire taxonomic range. Family classification is used for sensitive identification, consistent annotation, and detection of annotation errors. The superfamily curation defines signature domain architecture and categorizes memberships to improve automated classification. To increase the amount of experimental annotation, the PIR has developed a bibliography system for literature searching, mapping, and user submission, and has conducted retrospective attribution of citations for experimental features. PIR also maintains NREF, a non-redundant reference database, and iProClass, an integrated database of protein family, function, and structure information.
PIR is a member of the UniProt Consortium that provides the central international resource on protein sequence and function. Located both at the University of Delaware and Georgetown University, PIR conducts research in biomedical text mining and ontology, computational systems biology, and bioinformatics cyberinfrastructure. The PIR web sites are freely accessible by researchers worldwide with over 4 million hits per month from over 100,000 unique sites.
Resource Type: Resource
Version: Latest Version
family, function, annotation, bioinformatic, biomedical, comuptational systems biology, cyberinfrastructure, database, genomic, mining, protein, protein bioinformatics, proteomic, research, scientific, sequence, structure, systems biology, taxonomic, tool, ontology, text
NLM, P41 LM05978
Additional Resource Types
database, data or information resource
Created 5 years ago by Anonymous