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Ligand-Gated Ion Channel Database

Database providing access to information about transmembrane proteins that exist under different conformations, with three primary subfamilies: the cys-loop superfamily, the ATP gated channels superfamily, and the glutamate activated cationic channels superfamily. Due to the lack of evolutionary relationship, these three superfamilies are treated separately. It currently contains 554 entries of ligand-activated ion channel subunits. In this database one may find: the nucleic and proteic sequences of the subunits. Multiple sequence alignments can be generated, and some phylogenetic studies of the superfamilies are provided. Additionally, the atomic coordinates of subunits, or portion of subunits, are provided when available. Redundancy is kept to a minimum, i.e. one entry per gene. Each entry in the database has been manually constructed and checked by a researcher of the field in order to reduce the inaccuracies to a minimum. NOTE: This database is not actively maintained anymore. People should not consider it as an up-to-date trustable resource. For any new work, they should consider using alternative sources, such as UniProt, Ensembl, Protein Databank etc.

URL: http://www.ebi.ac.uk/compneur-srv/LGICdb/

Resource ID: nif-0000-00037     Resource Type: Resource     Version: Latest Version

Keywords

equilibrium, extracellular, gabaa, gated, gene, genetics, 3d model, alignment, anionic, atomic, atp, cationic, cellular, molecular, channel, compartment, computation, conformation, coordinate, cys-loop, glutamate, glycine, histamine, homologous, ion, ion channel, ligand, membrane, nicotinic, nucleic acid, phylogenetic, pore, portion, proteic, nucleic acid, protein, phylogeny, receptor, segment, sequence, sequence data, serotonin, subunit, superfamily, transmembrane

Comment

Access: Open
Reuse: Open- http://www.ebi.ac.uk/compneur-srv/LGICdb/FAQ.php for information
Start date: 1994
Type: Disciplinary
Deposit: Closed
(info provided by re3data.org)

Additional Resource Types

database

Supercategory

Resource

Resource Status

Last checked up;

Abbreviation

LGICdb

Synonyms

LGIC Database

Parent Organization

Funding Information

College of France; Paris; France, Centre National de la Recherche Scientifique, European Union, Biotech and Biomed contracts, French Ministry of Higher Education and Research, Institut Pasteur,

Curation Status

curated

Listed By

re3data.org

Publication Link

http://lenoverelab.org/perso/lenov/PUBLIS/Lenov1999a.pdf

Original Submitter

Anonymous

Version Status

Curated

Submitted On

12:00am September 21, 2010

Originated From

SciCrunch

Changes from Previous Version

First Version

Version 1

Created 5 years ago by Anonymous