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Ligand-Gated Ion Channel Database

Database providing access to information about transmembrane proteins that exist under different conformations, with three primary subfamilies: the cys-loop superfamily, the ATP gated channels superfamily, and the glutamate activated cationic channels superfamily. Due to the lack of evolutionary relationship, these three superfamilies are treated separately. It currently contains 554 entries of ligand-activated ion channel subunits. In this database one may find: the nucleic and proteic sequences of the subunits. Multiple sequence alignments can be generated, and some phylogenetic studies of the superfamilies are provided. Additionally, the atomic coordinates of subunits, or portion of subunits, are provided when available. Redundancy is kept to a minimum, i.e. one entry per gene. Each entry in the database has been manually constructed and checked by a researcher of the field in order to reduce the inaccuracies to a minimum. NOTE: This database is not actively maintained anymore. People should not consider it as an up-to-date trustable resource. For any new work, they should consider using alternative sources, such as UniProt, Ensembl, Protein Databank etc.

URL: http://www.ebi.ac.uk/compneur-srv/LGICdb/

Resource ID: nif-0000-00037     Resource Type: Resource     Version: Latest Version


equilibrium, extracellular, gabaa, gated, gene, genetics, 3d model, alignment, anionic, atomic, atp, cationic, cellular, molecular, channel, compartment, computation, conformation, coordinate, cys-loop, glutamate, glycine, histamine, homologous, ion, ion channel, ligand, membrane, nicotinic, nucleic acid, phylogenetic, pore, portion, proteic, nucleic acid, protein, phylogeny, receptor, segment, sequence, sequence data, serotonin, subunit, superfamily, transmembrane


Access: Open
Reuse: Open- http://www.ebi.ac.uk/compneur-srv/LGICdb/FAQ.php for information
Start date: 1994
Type: Disciplinary
Deposit: Closed
(info provided by re3data.org)

Additional Resource Types




Resource Status

Last checked up;




LGIC Database

Parent Organization

Funding Information

College of France; Paris; France, Centre National de la Recherche Scientifique, European Union, Biotech and Biomed contracts, French Ministry of Higher Education and Research, Institut Pasteur,

Curation Status


Listed By


Publication Link


Original Submitter


Version Status


Submitted On

12:00am September 21, 2010

Originated From


Changes from Previous Version

First Version

Version 1

Created 5 years ago by Anonymous