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InParanoid: Eukaryotic Ortholog Groups

Collection of pairwise comparisons between 100 whole genomes generated by a fully automatic method for finding orthologs and in-paralogs between TWO species. Ortholog clusters in the InParanoid are seeded with a two-way best pairwise match, after which an algorithm for adding in-paralogs is applied. The method bypasses multiple alignments and phylogenetic trees, which can be slow and error-prone steps in classical ortholog detection. Still, it robustly detects complex orthologous relationships and assigns confidence values for in-paralogs. The original data sets can be downloaded.

URL: http://inparanoid.sbc.su.se/cgi-bin/index.cgi

Resource ID: nif-0000-03024     Resource Type: Resource     Version: Latest Version


protein, ortholog, genome, drosophila pseudoobscura, duplication, entamoeba histolytica, escherichia colik12, eukaryotic, gasterosteus aculeatus, gene, aedes aegypti, apis mellifera, bos taurus, caenorhabditis remanei, candida glabrata, canis familiaris, ciona intestinalis, cryptococcus neoformans, debaromyces hansenii, dictyostelium discoideum, genomic, homolog, inparalog, kluyveromyces lactis, macaca mulatta, monodelphis domestica, orthology, oryza sativa, outparalog, proteome, tetraodon nigroviridis, xenopus tropicalis, blast, proteome, ortholog cluster, cluster, in-paralog, paralog, automatic clustering, genome comparison

Curation Status



Acknowledgement requested


escherichia coli, anopheles gambiae, caenorhabditis briggsae, caenorhabditis elegans, drosophila melanogaster, zebrafish, takifugu rubripes, chicken, human, mouse, chimpanzee, rat, oryza sativa, plasmodium falciparum, arabidopsis thaliana, saccharomyces cerevisiae, schizosaccharomyces pombe, eukaryota

Resource PubMed IDs

PMID: 19043069, PMID: 20498707, PMID: 20883526, PMID: 21647448, PMID: 21738795, PMID: 21846611, PMID: 22465851, PMID: 22761991, PMID: 23418180, PMID: 23758924, PMID: 23922823, PMID: 24023804, PMID: 24397480, PMID: 24455408, PMID: 24604738, PMID: 24646378, PMID: 24968325, PMID: 25075304




Inparanoid eukaryotic ortholog database

Parent Organization

Resource Status

Last checked up;

Funding Information

Swedish Research Council, Karolinska Institutet; Stockholm; Sweden, Pfizer Corporation,

Additional Resource Types

database, data analysis service

Old URLs




Original Submitter


Version Status


Submitted On

12:00am September 21, 2010

Originated From


Changes from Previous Version

First Version

Version 1

Created 5 years ago by Anonymous