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High Throughput Genomic Sequences Division

Database of high-throughput genome sequences from large-scale genome sequencing centers, including unfinished and finished sequences. It was created to accommodate a growing need to make unfinished genomic sequence data rapidly available to the scientific community in a coordinated effort among the International Nucleotide Sequence databases, DDBJ, EMBL, and GenBank. Sequences are prepared for submission by using NCBI''''s software tools Sequin or tbl2asn. Each center has an FTP directory into which new or updated sequence files are placed. Sequence data in this division are available for BLAST homology searches against either the htgs database or the month database, which includes all new submissions for the prior month. Unfinished HTG sequences containing contigs greater than 2 kb are assigned an accession number and deposited in the HTG division. A typical HTG record might consist of all the first-pass sequence data generated from a single cosmid, BAC, YAC, or P1 clone, which together make up more than 2 kb and contain one or more gaps. A single accession number is assigned to this collection of sequences, and each record includes a clear indication of the status (phase 1 or 2) plus a prominent warning that the sequence data are unfinished and may contain errors. The accession number does not change as sequence records are updated; only the most recent version of a HTG record remains in GenBank.

URL: http://www.ncbi.nlm.nih.gov/HTGS/

Resource ID: nif-0000-20943     Resource Type: Resource     Version: Latest Version


gap, gene, accession, arabidopsis, bac, biological, c. elegans, clone, contig, cosmid, dna, genomic, high-throughput, homology, homo sapiens, invertebrate, nematode, nucleotide, p1, plant, primate, sequence, structure, taxonomy, yac, genome, sequence, nucleotide sequence, dna sequence, nucleotide, dna, gold standard

Additional Resource Types

Database, Data Repository


arabidopsis, human, caenorhabditis elegans, others

Publication Link


Related To



HTG Sequences, HTG Division

Parent Organization


HTG Sequence, HTG database, NCBI High-Throughput Genomic Sequences, High-Throughput Genomic Sequences, HTG GenBank Division


The community can contribute to this resource



Original Submitter


Version Status


Submitted On

12:00am October 19, 2010

Originated From


Changes from Previous Version

    No Changes

    Version 4

    Created 2 weeks ago by Christie Wang

    Version 3

    Created 3 weeks ago by Christie Wang

    Version 2

    Created 3 weeks ago by Christie Wang

    Version 1

    Created 5 years ago by Anonymous