A community-based bioinformatics resource consisting of three structured controlled vocabularies (ontologies) for the annotation of gene products with respect to their molecular function, cellular component, and biological role in a species-independent manner. This initiative to standardize the representation of gene and gene product attributes across species and databases is an effort to address the need for consistent descriptions of gene products in different databases. The Gene Ontology project encourages input from the community into both the content of the GO and annotation using GO.
There are three separate aspects to this effort: first, they write and maintain the ontologies themselves; second, they make cross-links between the ontologies and the genes and gene products in the collaborating databases; and third, they develop tools that facilitate the creation, maintenance and use of ontologies.
The controlled vocabularies are structured so that you can query them at different levels: for example, you can use GO to find all the gene products in the mouse genome that are involved in signal transduction, or you can zoom in on all the receptor tyrosine kinases. This structure also allows annotators to assign properties to gene products at different levels, depending on how much is known about a gene product.
Resource Type: Resource
Version: Latest Version
gene ontology, gene, annotation, gene annotation, biological process, cellular component, molecular function, bioinformatics, gene product, bioinformatics, obo, gold standard
Contact: Go Helpdesk, go-helpdesk (at) ebi.ac.uk
BioPortal, OBO, OMICtools
The community can contribute to this resource, Acknowledgement required
GO - Gene Ontology, Gene Ontology, the Gene Ontology, GO - Gene Ontology, GO REF
NHGRI, European Union, RTD Programme Quality of Life and Management of Living Resources, AstraZeneca, 5P41HG002273-09, QLRI-CT-2001-00981, QLRI-CT-2001-00015
Additional Resource Types
ontology, international standard specification, database
NIF Data Federation, Monarch Initiative, Aging Portal
Created 4 years ago by Anonymous