It provides information about the evolutionary history of the residues on the interface and represents which residues are highly conserved on the interface. In this way, functionally and structurally important residues on the interface can be distinguished.
Hotsprint contains overall properties of the interface such as number of computational hot spots on the interface, number of conserved residues on the interface, average conservation score of interface residues and buried ASA of the interface. Additionally, residues of the interface along with their position, name, conservation score, ASA in monomer, ASA in complex, type (contacting interface residue, neighboring interface residue or none) and whether the residue is computational hot spot or not information are presented.
Resource Type: Resource
Version: Latest Version
evolution of proteins, protein residues, surface residues
Additional Resource Types
Created 5 years ago by Anonymous