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Comparative Toxicogenomics Database

A public database that enhances understanding about the effects of environmental chemicals on human health. Integrated GO data and a GO browser add functionality to CTD by allowing users to understand biological functions, processes and cellular locations that are the targets of chemical exposures. CTD includes curated data describing cross-species chemical����??gene/protein interactions and chemical����?? and gene����??disease associations to illuminate molecular mechanisms underlying variable susceptibility and environmentally influenced diseases. These data will also provide insights into complex chemical����??gene and protein interaction networks. Use CTD to discover: # What human diseases are associated with a gene/protein? # What human diseases are associated with a chemical? # What genes/proteins interact with a chemical? # What chemicals interact with a gene/protein? # What references report a chemical����??gene/protein interaction? # What cellular functions (GO terms) are affected by a chemical?

URL: http://ctdbase.org/

Resource ID: nif-0000-02683     Resource Type: Resource     Version: Latest Version


environment, chemical, disease, gene, pathway, protein, interaction, animal model, ontology, annotation, toxin, ontology or annotation browser

Funding Information

Pfizer, American Chemistry Council, NCRR, NIEHS, ES014065, R01 ES019604, P20 RR016463

Additional Resource Types

database, data analysis service

Used By

NIF Data Federation, Monarch Initiative

Alternate URLs




Related To

Resource:GO Resource:OMICtools



Parent Organization

Alternate IDs


Related Application

Research, Education

Resource PubMed IDs

PMID: 15945148, PMID: 18845002, PMID: 19590694, PMID: 19814812, PMID: 20198196, PMID: 21478484, PMID: 21846611, PMID: 21912624, PMID: 21933848, PMID: 22067452, PMID: 22125387, PMID: 22324457, PMID: 22434833, PMID: 22434847, PMID: 22748168, PMID: 23625301, PMID: 24288140, PMID: 24565337, PMID: 24919658, PMID: 25093322, PMID: 25149292, PMID: 25326818, PMID: 25360770

Resource Status

Last checked up;


CTD - Comparative Toxicogenomics Database

Curation Status


Listed By

3DVC, Gene Ontology Tools


Public, Free for academic use, Acknowledgement required


human, mouse, rat, chicken, zebrafish, dog

Original Submitter


Version Status


Submitted On

12:00am October 19, 2010

Originated From


Changes from Previous Version

First Version

Version 1

Created 4 years ago by Anonymous