X
Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.

CRE Binding-protein Target Gene Database

CREB target gene database that uses a multi-layered approach to predict, validate and characterize CREB target genes. For each gene, the database tries to provide the following information: 1. CREB binding sites on the promoters 2. Promoter occupancy by CREB 3. Gene activation by cAMP in tissues CREB seems to occupy a large number of promoters in the genome (up to ~5000 in human), and the profiles for CREB promoter occupancy are very similar in different human tissues. However, only a small proportion of CREB occupied genes are induced by cAMP in any cell type, possibly reflecting the requirement of additional regulatory partners that assist in recruitment of the transcriptional apparatus. To use the database, choose the species, select the table you want to search, leave field ('All') and type in the gene you want to search. A table listing the search results will be returned, followed by the description of the table. If no search result is returned, try the official gene symbol or gene ID (locuslink number) from NCBI Entrez Gene to search. Sponsors: This work was supported by National Institutes of Health Grants GM RO1-037828 (to M.M.) and DK068655 (to R.A.Y.).

URL: http://natural.salk.edu/CREB/

Resource ID: nif-0000-10201     Resource Type: Resource     Version: Latest Version

Keywords

expression, gene, activation, camp, camp-response element binding protein (creb), cell, cellular, coactivator, cyclic amp response element binding protein, hormone, human, in vivo, methylation, mouse, nutrient, phosphorylation, promoter, rat, regulatory, rna, signaling, target gene, tissue, transcription

Additional Resource Types

database

Resource PubMed IDs

PMID: 19680447, PMID: 21853033, PMID: 23166526, PMID: 25309323

Synonyms

CREB Database

Comment

Last updated May 02, 2005

Parent Organization

Curation Status

uncurated

Supercategory

Resource

Resource Status

Last checked down;

Original Submitter

Anonymous

Version Status

Curated

Submitted On

12:00am September 21, 2010

Originated From

SciCrunch

Changes from Previous Version

First Version

Version 1

Created 5 years ago by Anonymous