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A curated protein-protein and genetic interaction repository of raw protein and genetic interactions from major model organism species, with data compiled through comprehensive curation efforts. The current version searches over 41,000 publications containing over 720,000 interactions (June 2014) and contributions are welcome. Complete coverage of the entire literature is maintained for budding yeast (S. cerevisiae), fission yeast (S. pombe) and thale cress (A. thaliana), and efforts to expand curation across multiple metazoan species are underway. Current curation drives are focused on particular areas of biology to enable insights into conserved networks and pathways that are relevant to human health. It provides interaction data to several model organism databases, resources such as Entrez-Gene, SGD, TAIR, FlyBase and other interaction meta-databases. The entire BioGRID 3.0 data collection may be downloaded in multiple file formats, including IMEx compatible PSI MI XML. For developers, BioGRID interactions are also available via a REST based Web Service and Cytoscape plugin.

URL: http://www.thebiogrid.org/

Resource ID: nif-0000-00432     Resource Type: Resource     Version: Latest Version


budding yeast, fission yeast, protein, gene, protein interaction, genetic interaction, model organism, interaction, dataset, gene annotation, phenotype, orthologous interaction, yeast, cellular interaction network, physical interaction, protein-peptide, protein-rna, protein-protein interaction, genetics, publication, raw protein, genetic interaction, web service, pathway, network, biology, gene mapping, statistics

Funding Information

NIH, BBSRC, Canadian Institutes of Health Research, R01 RR024031

Additional Resource Types

database, software resource, data repository

Used By

NIF Data Federation, Monarch Initiative

Alternate IDs


Related To

Resource:Cytoscape, Resource:PSI-MI



Parent Organization

Related Application



saccharomyces cerevisiae, schizosaccharomyces pombe, arabidopsis thaliana, metazoa, human, mouse, caenorhabditis elegans, drosophila melanogaster, other


Biological General Repository for Interaction Datasets


Start date: 2003
Type: Disciplinary
Deposit: Accepting data for deposit - http://wiki.thebiogrid.org/doku.php/contribute#send_us_your_interaction_data

Listed By

re3data.org, OMICtools, DataCite


Public, Free, Only for research, The community can contribute to this resource



Original Submitter


Version Status


Submitted On

12:00am September 20, 2010

Originated From


Changes from Previous Version

First Version

Version 1

Created 5 years ago by Anonymous