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Organism Name
C57BL/6J-Ptpn6m1Btlr/Mmucd
RRID:MMRRC_015198-UCD RRID Copied  
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=15198

Proper Citation: RRID:MMRRC_015198-UCD

Description: Mus musculus with name C57BL/6J-Ptpn6m1Btlr/Mmucd from MMRRC.

Species: Mus musculus

Notes: Research areas: Apoptosis, Cancer, Cell Biology, Dermatology, Hematology, Immunology and Inflammation, Models for Human Disease, Virology; Mutation Type: chemically induced mutation ; Collection: Beutler Mutagenetix

Phenotype: increased neutrophil cell number [MP:0000219]| ulcerated paws [MP:0000578]| enlarged spleen [MP:0000691]| increased inflammatory response [MP:0001846]| lung inflammation [MP:0001861]| salivary gland inflammation [MP:0001870]| decreased susceptibility to bacterial infection [MP:0002411]| increased IgM level [MP:0002494]| increased erythroid progenitor cell number [MP:0003135]| increased anti-chromatin antibody level [MP:0004829]| decreased mature B cell number [MP:0008211]| abnormal myeloid leukocyte morphology [MP:0008250]| decreased susceptibility to bacterial infection induced morbidity/mortality [MP:0009789]

Affected Gene: Ptpn6

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Data and Source Information

Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/

Source Database: Mutant Mouse Resource and Research Center (MMRRC)