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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=153323320
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Live Animals; Cryopreserved Embryo; Cryorecovery (as of 2023-10-25)
Alternate IDs: RGD_153323320
Notes: Origin: as for MNR except selection was for high defecation response in the open field. To Harrington in 1965 at F25 and to NIH in 1964 at F18+ (Hansen et al 1982). Now is available at Rat Resource & Research Center Rat Resource and Research Center, RGD HRDP, contact HRDP
Proper citation: 0000173 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1358632
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo (as of 2019-02-20)
Alternate IDs: RGD_1358632, 1358632, RRRC_691, RRRC_0691, RRRC_00691
Notes: This strain has been selected for high open-field defecation (a test of emotional reactivity). The underlying genetic basis for this phenotype is not known. Originally selected by Broadhurst in 1954 for high open-field defacation (OFD) response in an open field. By Broadhurst to Harrington at the University of Northern Iowa at generation 25 in 1965. Rat Resource and Research Center
Proper citation: RRID:RRRC_00691 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=70509
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Sperm
Alternate IDs: RGD_70509, 70509, RRRC_158, RRRC_0158, RRRC_00158
Notes: Curtiss and Dunning 1920 at Columbia University Institute for Cancer Research,To Heston 1949 (Billingham and Silvers 1959). To National Institutes of Health in 1951 (Hansen et al 1982). Subsequent sublines from Dunning or NIH. NIH Autoimmune Rat Model Repository and Development Center, Rat Resource and Research Center
Proper citation: RRID:RRRC_00158 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10040
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_10040, 10040, RRRC_56, RRRC_056, RRRC_0056, RRRC_00056
Notes: Originated from a Sprague-Dawley outbred colony developed by LK Dahl, Brookhaven National Laboratories, Upton, New York, selected for resistance to salt-induced hypertension (Dahl et al 1962a,b). Rat Resource and Research Center
Proper citation: RRID:RRRC_00056 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1559036
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2019-02-01)
Alternate IDs: RGD_1559036, 1559036, RRRC_54, RRRC_054, RRRC_0054, RRRC_00054
Notes: Lewis rats from Tokyo Medical Insitute to Seiwa Institute of Experimental Animals, Hydrocephalus was found the rats at F27 in 1980, these were sent to Dr. Yasutaka Noda at Center for Animal Experiments, Kurume University, The hydrocephalus rat strains have been maintained out by selective breeding. National BioResource Project for the Rat in Japan, Rat Resource and Research Center
Proper citation: RRID:RRRC_00054 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482256
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryorecovery (as of 2019-02-01)
Alternate IDs: RGD_6482256, 6482256, RRRC_537, RRRC_0537, RRRC_00537
Notes: Developed from selective breeding of outbred Wistar rats. Selectively bred over six generations for increased intravenous drug self-administration with subsequent inbreeding within this strain over six generations. Rat Resource and Research Center
Proper citation: RRID:RRRC_00537 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2306717
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Sperm; Cryorecovery (as of 2018-11-12)
Alternate IDs: RGD_2306717, 2306717, RRRC_787, RRRC_0787, RRRC_00787
Notes: These originated from the Worcester colony from the rats that were sent from Ottawa to Worcester in 1977. Now maintained at University of Toronto, Canada. Rat Resource and Research Center
Proper citation: RRID:RRRC_00787 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482247
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2022-10-18)
Alternate IDs: RGD_6482247, 6482247, RRRC_60, RRRC_060, RRRC_0060, RRRC_00060
Notes: Cross between F344 (lean phenotype) and SDDIO (diet-induced obese phenotype) then inbred for 6 generations with maintenance of obese phenotype. Rat Resource and Research Center
Proper citation: RRID:RRRC_00060 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695055
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: RGD_14695055, 14695055, RRRC_794, RRRC_0794, RRRC_00794
Notes: Inbred hypertension model linked to a mutation in Add1 gene that has been validated as one of the genes linked to hypertension in numerous human genetic studies. Inbred strain originally developed by Dr. Bianchi in Milan in 1979. Rat Resource and Research Center
Proper citation: RRID:RRRC_00794 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11667072
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_11667072, 11667072, RRRC_538, RRRC_0538, RRRC_00538
Notes: This phenotype arose spontaneously during the third generation of selective breeding for decreased intravenous drug self-administration in Wistar rats (see RGD:6482259). After 10 weeks of age no drug administration is needed to see phenotype in which animals exhibits motor abnormalities with degenerative changes in cerebellar Purkinje cells. It appears to be transmitted in an autosomal recessive pattern. Animals have an abnormal swaying gait, which is readily identified as a slow (2 to 3 cycles per second) tremor. Rat Resource and Research Center
Proper citation: RRID:RRRC_00538 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150429818
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery (as of 2021-09-30)
Alternate IDs: RGD_150429818, 150429818, RRRC_562, RRRC_0562, RRRC_00562
Notes: Inbred from a single pair of SsN line rats obtained from Harlan Sprague Dawley (Alabama colony). Maintained at the Medical College of Wisconsin since 1995. To confirm homozygosity, the strain was tested with 200 microsatellite markers (genome-wide scan at 20cM) all of which were homozygous for all regions tested (Cowley et al. 2000, Physiol. Genomics. 2:107-115). This strain was maintained at RRRC. Rat Resource & Research Center
Proper citation: RRID:RRRC_00562 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11667081
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_11667081, 11667081, RRRC_784, RRRC_0784, RRRC_00784
Notes: Point mutation in Myo5a (Chromosome 8, end of exon 4)identified in In Berlin-Druckrey (BDIV) shaker rats Rat Resource and Research Center
Proper citation: RRID:RRRC_00784 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9999145
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: RGD_9999145, 9999145, RRRC_734, RRRC_0734, RRRC_00734
Notes: The F344/NCr rat strain was received into the NIH Genetic Resources program in 1987, now maintained at NCI Animal production program Rat Resource and Research Center
Proper citation: RRID:RRRC_00734 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7245556
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: RGD_7245556, 7245556, RRRC_664, RRRC_0664, RRRC_00664
Notes: WKHT rats are derived from a cross between SHR and WKY. Brother/sister inbreeding of the hybrids and successive generations was performed, selecting for the hypertension, but not the behavioral hyperactivity, of the SHR. Rat Resource and Research Center
Proper citation: RRID:RRRC_00664 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10000
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery
Alternate IDs: RGD_10000, 10000, RRRC_142, RRRC_0142, RRRC_00142
Notes: Curtiss and Dunning 1926 at the Columbia University Institute for Cancer Research. To Heston 1945 at F30, to National Institutes of Health 1950 at F41. Subsequent sublines from Dunning or NIH. Donated to RRRC from NIH Animal Genetic Resource Bank (NIHAGR) Rat Resource and Research Center
Proper citation: RRID:RRRC_00142 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=153323320
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Live Animals; Cryopreserved Embryo; Cryorecovery (as of 2023-10-25)
Alternate IDs: RGD_153323320, 153323320, RRRC_00173
Notes: Origin: as for MNR except selection was for high defecation response in the open field. To Harrington in 1965 at F25 and to NIH in 1964 at F18+ (Hansen et al 1982). Now is available at Rat Resource & Research Center Rat Resource and Research Center, RGD HRDP, contact HRDP
Proper citation: RRID:RRRC_00173 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=629509
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Live Animals; Cryorecovery
Alternate IDs: RGD_629509, 629509, RRRC_293, RRRC_0293, RRRC_00293
Notes: An outbred stock of fawn hooded rats introduced into Europe by Tschopp in the early 1970s. Maintained as an outbred stock until the mid-1980s, then brother x sister mating initiated by A.P. Provoost to produce two strains designated FHH (also known as FHR) and FHL, which differ in hypertension and proteinuria. The colony was transferred to Erasmus University. Rat Resource and Research Center, RGD HRDP, contact HRDP
Proper citation: RRID:RRRC_00293 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2307319
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo
Alternate IDs: RGD_2307319, 2307319, RRRC_171, RRRC_0171, RRRC_00171
Notes: Wistar rats with brother x sister mating and selection for low systolic blood pressure as a normotensive control for MHS. Rat Resource and Research Center
Proper citation: RRID:RRRC_00171 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482676
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_6482676, 6482676, RRRC_440, RRRC_0440, RRRC_00440
Notes: The Occidental LoS (low-saccharin-consuming) rat strain was developed from a male Holtzman Sprague-Dawley rat that did not voluntarily consume saccharin. This male was mated to several Holtzman Sprague-Dawley females and offspring displaying low saccharin consumption were selected. Selective breeding was continued in which offspring with low saccharin consumption (see phenotyping protocol) were bred. To maintain the outbred status of this colony the donor backcrosses to Hsd:SD every 4-6 generations. Rat Resource and Research Center
Proper citation: RRID:RRRC_00440 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1578695
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_1578695, 1578695, RRRC_68, RRRC_068, RRRC_0068, RRRC_00068
Notes: Selective breeding of Long-Evans in active two-way shuttle box for high avoidance resulted in these SHA rats. Rat Resource and Research Center
Proper citation: RRID:RRRC_00068 Copy
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