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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00000072
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; avEx122.
Alternate IDs: WB-STRAIN:AG175, CGC_AG175
Notes: avEx122 [(pAG126) lpin-1p::GFP::lpin-1::lpin-1 3'UTR + unc-119(+)]. No GFP expression detected in germline.
Proper citation: RRID:WB-STRAIN:WBStrain00000072 Copy
http://www.wormbase.org/db/get?name=WBStrain00000073
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; avEx123.
Alternate IDs: WB-STRAIN:AG176, CGC_AG176
Notes: avEx123 [lpin-1p::GFP::his-58::lpin-1 3'UTR + unc-119(+)]. No GFP expression detected in germline.
Proper citation: RRID:WB-STRAIN:WBStrain00000073 Copy
http://www.wormbase.org/db/get?name=WBStrain00000039
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; staIs2.
Alternate IDs: WB-STRAIN:ABR7, CGC_ABR7
Notes: staIs2 [pie-1p::rbr-2::GFP + unc-119(+)]. Extended longevity. Maintain under normal conditions. Reference: This strain was used as LC Ppie-1::rbr-2::GFP (#3) in Greer EL et al Nature 2010 doi: 10.1038/nature09195.
Proper citation: RRID:WB-STRAIN:WBStrain00000039 Copy
http://www.wormbase.org/db/get?name=WBStrain00000038
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; staIs1.
Alternate IDs: WB-STRAIN:ABR5, CGC_ABR5
Notes: staIs1 [pie-1p::GFP + unc-119(+)]. Superficially wild-type. Maintain under normal conditions. Reference: This strain was used as the empty vector control in Greer EL et al Nature 2010 doi: 10.1038/nature09195.
Proper citation: RRID:WB-STRAIN:WBStrain00000038 Copy
http://www.wormbase.org/db/get?name=WBStrain00000050
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; asIs2.
Alternate IDs: WB-STRAIN:AD189, CGC_AD189
Notes: asIs2 [pie-1p::GFP::egg-1 + unc-119(+)]. Oocyte membranes are GFP+.
Proper citation: RRID:WB-STRAIN:WBStrain00000050 Copy
http://www.wormbase.org/db/get?name=WBStrain00000051
Source Database: WormBase (WB)
Affected Genes: WBGene00004027(pie-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004027(pie-1), WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; asIs1.
Alternate IDs: WB-STRAIN:AD200, CGC_AD200
Notes: asIs1 [pie-1p::GFP::egg-3 + unc-119(+)].
Proper citation: RRID:WB-STRAIN:WBStrain00000051 Copy
http://www.wormbase.org/db/get?name=WBStrain00000127
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; niDf199 IV; armEx58.
Alternate IDs: WB-STRAIN:AGK233, CGC_AGK233
Notes: armEx58 [WRM0611aH08-Del8mer + unc-119(+)]. Pick non-Unc to maintain. This strain contains a transgenic array that expresses a derivative WRM0611aH08 fosmid. The WRM0611aH08 fosmid contains the niDF199 locus (around 4 kb) that is deleted in the natural C. elegans isolate strain JU258. JU258 worms lack specific 21U-RNAs normally present in N2 worms due to this deletion of the niDF199 locus. This derivative fosmid construct lacks the upstream 8-mer motif (CTGTTTCA) next to 21U-3372. The expression of this individual 21U-RNA is lost in transgenic animals. unc-119(ed3) was crossed into JU258, the niDf199IV deletion was confirmed by PCR, and these Unc worms were used for bombardment. Reference: Cecere G, et al. Mol Cell. 2012 Sep 14;47(5):734-45.|"Made_by: Cecere & Mansisidore"
Proper citation: RRID:WB-STRAIN:WBStrain00000127 Copy
http://www.wormbase.org/db/get?name=WBStrain00000129
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)|WBGene00006975(zfp-1)
Genomic Alteration: WBGene00006843(unc-119), WBGene00006975(zfp-1)
Availability: available
Source References: EMPTY
Synonyms: zfp-1(ok554) unc-119(ed3) III; armEx14.
Alternate IDs: WB-STRAIN:AGK280, CGC_AGK280
Notes: armEx14 [PHD1-PHD2::FLAG + zfp-1(short isoform) + unc-119(+)]. Pick non-Unc animals to maintain. The fosmid-based armEx14 transgene rescues zfp-1(ok554)/nDf17 lethality. Reference: Avgousti DC, et al. Mol Cell Biol. 2013 Mar;33(5):999-1015.|"Made_by: Cecere & Mansisidore"
Proper citation: RRID:WB-STRAIN:WBStrain00000129 Copy
http://www.wormbase.org/db/get?name=WBStrain00000167
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; bafIs63.
Alternate IDs: WB-STRAIN:ALF63, CGC_ALF63
Notes: bafIs63 [lin-42p(mut)::GFP + unc-119(+)]. lin-42p(mut)::GFP reporter consists of 2 kb upstream of lin-42a isoform subcloned into modified pPD95.75 vector also carrying unc-119(+); all potential DAF-12 binding sites have been mutated. Reference: Hochbaum D, et al. PLoS Genet. 2011 Jul;7(7):e1002179.
Proper citation: RRID:WB-STRAIN:WBStrain00000167 Copy
http://www.wormbase.org/db/get?name=WBStrain00000168
Source Database: WormBase (WB)
Affected Genes: WBGene00000908(daf-12)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00000908(daf-12), WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; daf-12(rh61rh411) X; bafIs62.
Alternate IDs: WB-STRAIN:ALF82, CGC_ALF82
Notes: bafIs62 [lin-42p::GFP + unc-119(+)]. lin-42p::GFP reporter consists of 2 kb upstream of lin-42a isoform subcloned into modified pPD95.75 vector also carrying unc-119(+). Array was crossed into strain ALF3 to create ALF82. Reference: Hochbaum D, et al. PLoS Genet. 2011 Jul;7(7):e1002179.
Proper citation: RRID:WB-STRAIN:WBStrain00000168 Copy
http://www.wormbase.org/db/get?name=WBStrain00000165
Source Database: WormBase (WB)
Affected Genes: WBGene00000908(daf-12)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00000908(daf-12), WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; daf-12(rh61rh411) X; bafIs9.
Alternate IDs: WB-STRAIN:ALF9, CGC_ALF9
Notes: bafIs9 [daf-12::TAP (fosmid) + unc-119(+)]; rescues both daf-12 and unc-119. TAP tag inserted into daf-12 fosmid. Reference: Hochbaum D, et al. PLoS Genet. 2011 Jul;7(7):e1002179.
Proper citation: RRID:WB-STRAIN:WBStrain00000165 Copy
http://www.wormbase.org/db/get?name=WBStrain00000212
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:37565483
Synonyms: ljSi2 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:AQ3236, CGC_AQ3236
Notes: ljSi2 [mec-7::GCaMP6m::SL2::TagRFP + unc-119(+)] II. GCaMP6m (13.693) and RFP expressed in touch receptor neurons (ALML/R, AVM, PVM, PLML/R). Dual expression of GCamp6m and RFP allows for ratio-metric corrections of motion artifacts. Reference: Cho Y, et al. Lab Chip. 2017 Jul 25;17(15):2609-2618.|"Made_by: Dr. William Schafer"
Proper citation: RRID:WB-STRAIN:WBStrain00000212 Copy
http://www.wormbase.org/db/get?name=WBStrain00000239
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: wamSi3 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:ARM3, CGC_ARM3
Notes: wamSi3 [eft-3p::mNeptune::unc-54 3'UTR + Cbr-unc-119(+)] II. Expresses a single copy of mNeptune from eft-3 promoter; construct utilizes the unc-54 terminator and 3'UTR. Can be used as a standard for multicolor imaging and quantitative microscopy. Reference: Sands B, et al. 2018. Translational Medicine of Aging Volume 2, January 2018, Pages 110.
Proper citation: RRID:WB-STRAIN:WBStrain00000239 Copy
http://www.wormbase.org/db/get?name=WBStrain00000245
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: wamSi118 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:ARM118, CGC_ARM118
Notes: wamSi118 [eft-3p::mCerulean3::unc-54 3'UTR + Cbr-unc-119(+)] II. Expresses a single copy of mCerulean3 from eft-3 promoter; construct utilizes the unc-54 terminator and 3'UTR. Can be used as a standard for multicolor imaging and quantitative microscopy. Reference: Sands B, et al. 2018. Translational Medicine of Aging Volume 2, January 2018, Pages 110.
Proper citation: RRID:WB-STRAIN:WBStrain00000245 Copy
http://www.wormbase.org/db/get?name=WBStrain00000241
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: wamSi7 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:ARM7, CGC_ARM7
Notes: wamSi7 [eft-3p::mTagRFP-T::unc-54 3'UTR + Cbr-unc-119(+)] II. Expresses a single copy of mTagRFP-T from eft-3 promoter; construct utilizes the unc-54 terminator and 3'UTR. Can be used as a standard for multicolor imaging and quantitative microscopy. Reference: Sands B, et al. 2018. Translational Medicine of Aging Volume 2, January 2018, Pages 110.
Proper citation: RRID:WB-STRAIN:WBStrain00000241 Copy
http://www.wormbase.org/db/get?name=WBStrain00000242
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:37857834
Synonyms: wamSi101 V; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:ARM101, CGC_ARM101
Notes: Supplementary_genotype wamSi101 (eft-3p::mTFP::unc-54 3'UTR + Cbr-unc-119 (+)) V unc-119(ed3) III|"wamSi101 [eft-3p::mTFP::unc-54 3'UTR + Cbr-unc-119(+)] V. Expresses a single copy of mTFP from eft-3 promoter; construct utilizes the unc-54 terminator and 3'UTR. Can be used as a standard for multicolor imaging and quantitative microscopy. Reference: Sands B, et al. 2018. Translational Medicine of Aging Volume 2, January 2018, Pages 110."
Proper citation: RRID:WB-STRAIN:WBStrain00000242 Copy
http://www.wormbase.org/db/get?name=WBStrain00000243
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; wamSi103 V.
Alternate IDs: WB-STRAIN:ARM103, CGC_ARM103
Notes: wamSi103 [eft-3p::mKO2::unc-54 3'UTR + Cbr-unc-119(+)] V. Expresses a single copy of mKO2 from eft-3 promoter; construct utilizes the unc-54 terminator and 3'UTR. Can be used as a standard for multicolor imaging and quantitative microscopy. Reference: Sands B, et al. 2018. Translational Medicine of Aging Volume 2, January 2018, Pages 110.
Proper citation: RRID:WB-STRAIN:WBStrain00000243 Copy
http://www.wormbase.org/db/get?name=WBStrain00000255
Source Database: WormBase (WB)
Affected Genes: WBGene00003055(lon-1)|WBGene00003918(par-3)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00003055(lon-1), WBGene00003918(par-3), WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: lon-1(e185) par-3(e2074) unc-119(ed3) III; zuIs45 V; sDp3(III;f)
Alternate IDs: WB-STRAIN:ATD3, CGC_ATD3
Notes: Made_by: Lawrence E. Small|"zuIs45 [nmy-2p::nmy-2::GFP + unc-119(+)] V. Pick wild-type to maintain. Worms carrying the sDp3 duplication are wild-type; animals that have lost the duplication are Lon Par (maternal effect lethal). Cross of JJ1473 and KK237. Unknown if unc-119(ed3) is still present or homozygous in background. Reference: Small LE & Dawes AT. Mol Biol Cell. 2017 Aug 1;28(16):2220-2231."
Proper citation: RRID:WB-STRAIN:WBStrain00000255 Copy
http://www.wormbase.org/db/get?name=WBStrain00000270
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: vizSi32 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:AUM2071, CGC_AUM2071
Notes: Made_by: Tokyo Furuta|"vizSi32 [cdk-2p(intron)::GFP::tbb-2 3 UTR + unc-119(+)] II. vizSi32 was inserted into ttTi5605 on Chr II using MosSci. Intron 1 of cdk-2 drives drives GFP expression in this transgene. Reference: Furuta T, et al. Development. 2018 May 14;145(10). pii: dev161042. doi: 10.1242/dev.161042."
Proper citation: RRID:WB-STRAIN:WBStrain00000270 Copy
http://www.wormbase.org/db/get?name=WBStrain00000271
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: vizSi34 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:AUM2073, CGC_AUM2073
Notes: Made_by: Tokyo Furuta|"vizSi34 [cdk-2p::GFP::tbb-2 3 UTR + unc-119(+)] II. Superficially wild-type. vizSi34 was inserted into ttTi5605 on Chr II using MosSci. Predicted cdk-2 promoter (from WormBase) drives GFP expression. Reference: Furuta T, et al. Development. 2018 May 14;145(10). pii: dev161042. doi: 10.1242/dev.161042."
Proper citation: RRID:WB-STRAIN:WBStrain00000271 Copy
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