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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://www.jax.org/strain/033869
Source Database: JAX Mice and Services
Affected Genes: triggering receptor expressed on myeloid cells 2|amyloid beta precursor protein|apolipoprotein E|bridging integrator 1
Genomic Alteration: endonuclease-mediated mutation 1; MODEL-AD Center|targeted mutation 1.1; MODEL-AD Center
Availability: embryo
Notes: gene symbol note: triggering receptor expressed on myeloid cells 2|amyloid beta precursor protein|apolipoprotein E|bridging integrator 1; mutant strain|congenic strain: Trem2|App|Apoe|APOE|Bin1
Proper citation: RRID:IMSR_JAX:033869 Copy
https://www.jax.org/strain/033757
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 7; Katharine Ellwood-Yen||NK3 homeobox 1|phosphatase and tensin homolog|gene trap ROSA 26; Philippe Soriano
Genomic Alteration: transgene insertion 7; Katharine Ellwood-Yen|targeted mutation 3; Hongkui Zeng|targeted mutation 4; Michael M Shen|targeted mutation 1; Hong Wu
Availability: embryo
Notes: gene symbol note: transgene insertion 7; Katharine Ellwood-Yen||NK3 homeobox 1|phosphatase and tensin homolog|gene trap ROSA 26; Philippe Soriano; mutant stock: Tg(ARR2/Pbsn-MYC)7Key||Nkx3-1|Pten|Gt(ROSA)26Sor
Proper citation: RRID:IMSR_JAX:033757 Copy
https://www.jax.org/strain/033756
Source Database: JAX Mice and Services
Affected Genes: phosphatase and tensin homolog|gene trap ROSA 26; Philippe Soriano||transformation related protein 53|NK3 homeobox 1
Genomic Alteration: targeted mutation 1; Hong Wu|targeted mutation 3; Hongkui Zeng|targeted mutation 3; Tyler Jacks|targeted mutation 4; Michael M Shen|targeted mutation 1; Anton Berns
Availability: embryo
Synonyms: STOCK Gt(ROSA)26Sor
Notes: gene symbol note: phosphatase and tensin homolog|gene trap ROSA 26; Philippe Soriano||transformation related protein 53|NK3 homeobox 1; mutant stock: Pten|Gt(ROSA)26Sor||Trp53|Nkx3-1
Proper citation: RRID:IMSR_JAX:033756 Copy
https://www.jax.org/strain/033753
Source Database: JAX Mice and Services
Affected Genes: |gene trap ROSA 26; Philippe Soriano|NK3 homeobox 1|breast cancer 1; early onset|phosphatase and tensin homolog
Genomic Alteration: targeted mutation 3; Hongkui Zeng|targeted mutation 4; Michael M Shen|targeted mutation 2; Chu-Xia Deng|targeted mutation 1; Hong Wu
Availability: embryo
Notes: gene symbol note: |gene trap ROSA 26; Philippe Soriano|NK3 homeobox 1|breast cancer 1; early onset|phosphatase and tensin homolog; mutant stock: |Gt(ROSA)26Sor|Nkx3-1|Brca1|Pten
Proper citation: RRID:IMSR_JAX:033753 Copy
https://www.jax.org/strain/033759
Source Database: JAX Mice and Services
Affected Genes: NK3 homeobox 1|SMAD family member 4|gene trap ROSA 26; Philippe Soriano||phosphatase and tensin homolog
Genomic Alteration: targeted mutation 4; Michael M Shen|targeted mutation 2.1; Chu-Xia Deng|targeted mutation 3; Hongkui Zeng|targeted mutation 1; Hong Wu
Availability: embryo
Notes: gene symbol note: NK3 homeobox 1|SMAD family member 4|gene trap ROSA 26; Philippe Soriano||phosphatase and tensin homolog; mutant stock: Nkx3-1|Smad4|Gt(ROSA)26Sor||Pten
Proper citation: RRID:IMSR_JAX:033759 Copy
https://www.jax.org/strain/033763
Source Database: JAX Mice and Services
Affected Genes: NK3 homeobox 1|gene trap ROSA 26; Philippe Soriano|phosphatase and tensin homolog
Genomic Alteration: targeted mutation 4; Michael M Shen|targeted mutation 2; Rosalie C Sears|targeted mutation 1; Hong Wu
Availability: embryo
Notes: gene symbol note: NK3 homeobox 1|gene trap ROSA 26; Philippe Soriano|phosphatase and tensin homolog; mutant stock: Nkx3-1|Gt(ROSA)26Sor|Pten
Proper citation: RRID:IMSR_JAX:033763 Copy
https://www.jax.org/strain/034029
Source Database: JAX Mice and Services
Affected Genes: synuclein; alpha|amyloid beta precursor protein|presenilin 1|TAR DNA binding protein|microtubule-associated protein tau
Genomic Alteration: endonuclease-mediated mutation 2; Cathy Lutz|endonuclease-mediated mutation 5; Michael Sasner|endonuclease-mediated mutation 1; Michael Sasner|endonuclease-mediated mutation 9; Cathy Lutz
Availability: embryo
Notes: gene symbol note: synuclein; alpha|amyloid beta precursor protein|presenilin 1|TAR DNA binding protein|microtubule-associated protein tau; mutant strain|congenic strain: Snca|App|Psen1|Tardbp|Mapt
Proper citation: RRID:IMSR_JAX:034029 Copy
https://www.jax.org/strain/034028
Source Database: JAX Mice and Services
Affected Genes: microtubule-associated protein tau|synuclein; alpha|TAR DNA binding protein
Genomic Alteration: endonuclease-mediated mutation 2; Cathy Lutz|endonuclease-mediated mutation 9; Cathy Lutz
Availability: embryo
Notes: gene symbol note: microtubule-associated protein tau|synuclein; alpha|TAR DNA binding protein; coisogenic strain|mutant strain: Mapt|Snca|Tardbp
Proper citation: RRID:IMSR_JAX:034028 Copy
https://www.jax.org/strain/034030
Source Database: JAX Mice and Services
Affected Genes: synuclein; alpha|presenilin 1|microtubule-associated protein tau|TAR DNA binding protein
Genomic Alteration: endonuclease-mediated mutation 2; Cathy Lutz|endonuclease-mediated mutation 1; Michael Sasner|endonuclease-mediated mutation 9; Cathy Lutz
Availability: embryo
Notes: gene symbol note: synuclein; alpha|presenilin 1|microtubule-associated protein tau|TAR DNA binding protein; mutant strain|congenic strain: Snca|Psen1|Mapt|Tardbp
Proper citation: RRID:IMSR_JAX:034030 Copy
https://www.jax.org/strain/034001
Source Database: JAX Mice and Services
Affected Genes: GRIP1 associated protein 1
Genomic Alteration: targeted mutation 1; Richard L Huganir
Availability: embryo
Synonyms: B6N.129-Gripap1
Notes: gene symbol note: GRIP1 associated protein 1; mutant strain|congenic strain: Gripap1
Proper citation: RRID:IMSR_JAX:034001 Copy
https://www.jax.org/strain/034545
Source Database: JAX Mice and Services
Affected Genes: apolipoprotein E|microtubule-associated protein tau|TAR DNA binding protein
Genomic Alteration: targeted mutation 1.1; MODEL-AD Center|endonuclease-mediated mutation 2; Cathy Lutz|endonuclease-mediated mutation 9; Cathy Lutz
Availability: embryo
Notes: gene symbol note: apolipoprotein E|microtubule-associated protein tau|TAR DNA binding protein; mutant strain: APOE|Apoe|Mapt|Tardbp
Proper citation: RRID:IMSR_JAX:034545 Copy
https://www.jax.org/strain/034543
Source Database: JAX Mice and Services
Affected Genes: apolipoprotein E|amyloid beta precursor protein|TAR DNA binding protein
Genomic Alteration: targeted mutation 1.1; MODEL-AD Center|endonuclease-mediated mutation 5; Michael Sasner|endonuclease-mediated mutation 9; Cathy Lutz
Availability: embryo
Notes: gene symbol note: apolipoprotein E|amyloid beta precursor protein|TAR DNA binding protein; mutant strain|congenic strain: APOE|Apoe|App|Tardbp
Proper citation: RRID:IMSR_JAX:034543 Copy
https://www.jax.org/strain/034655
Source Database: JAX Mice and Services
Affected Genes: transgene insertion M; Raghu Kalluri
Genomic Alteration: transgene insertion M; Raghu Kalluri
Availability: embryo
Synonyms: C57BL/6-Tg(Fap-TK)MRkl/J
Notes: gene symbol note: transgene insertion M; Raghu Kalluri; mutant strain|congenic strain: Tg(Fap-TK)MRkl
Proper citation: RRID:IMSR_JAX:034655 Copy
https://www.jax.org/strain/034810
Source Database: JAX Mice and Services
Affected Genes: secreted phosphoprotein 1
Genomic Alteration: targeted mutation 1; Brigid L Hogan
Availability: embryo
Notes: gene symbol note: secreted phosphoprotein 1; mutant strain: Spp1
Proper citation: RRID:IMSR_JAX:034810 Copy
https://www.jax.org/strain/039205
Source Database: JAX Mice and Services
Affected Genes: neurogenin 1
Genomic Alteration: targeted mutation 1; Carol Schuurmans
Availability: embryo
Synonyms: B6N.B6J-Neurog1
Notes: gene symbol note: neurogenin 1; mutant strain|congenic strain: Neurog1
Proper citation: RRID:IMSR_JAX:039205 Copy
https://www.jax.org/strain/039503
Source Database: JAX Mice and Services
Affected Genes: inhibitor of growth family; member 4
Genomic Alteration: targeted mutation 1.1; Anne K Voss
Availability: embryo
Notes: gene symbol note: inhibitor of growth family; member 4; congenic strain: Ing4
Proper citation: RRID:IMSR_JAX:039503 Copy
https://www.jax.org/strain/039285
Source Database: JAX Mice and Services
Affected Genes: purinergic receptor P2Y; G-protein coupled 10
Genomic Alteration: endonuclease-mediated mutation 1; Jackson
Availability: embryo
Notes: gene symbol note: purinergic receptor P2Y; G-protein coupled 10; coisogenic strain|mutant strain: P2ry10
Proper citation: RRID:IMSR_JAX:039285 Copy
https://www.jax.org/strain/040202
Source Database: JAX Mice and Services
Affected Genes: protein phosphatase 4 regulatory subunit 3C2
Genomic Alteration: endonuclease-mediated mutation 1; Jackson
Availability: embryo
Notes: gene symbol note: protein phosphatase 4 regulatory subunit 3C2; coisogenic strain|mutant strain: Ppp4r3c2
Proper citation: RRID:IMSR_JAX:040202 Copy
https://www.jax.org/strain/039976
Source Database: JAX Mice and Services
Affected Genes: |Myc proto-oncogene; bHLH transcription factor|gene trap ROSA 26; Philippe Soriano|Sad1 and UNC84 domain containing 1
Genomic Alteration: targeted mutation 5; Jeremy Nathans
Availability: embryo
Notes: gene symbol note: |Myc proto-oncogene; bHLH transcription factor|gene trap ROSA 26; Philippe Soriano|Sad1 and UNC84 domain containing 1; inbred strain: |Myc|Gt(ROSA)26Sor|Sun1
Proper citation: RRID:IMSR_JAX:039976 Copy
https://www.jax.org/strain/039960
Source Database: JAX Mice and Services
Affected Genes: rabaptin; RAB GTPase binding effector protein 1
Genomic Alteration: endonuclease-mediated mutation 1; Jackson
Availability: embryo
Notes: gene symbol note: rabaptin; RAB GTPase binding effector protein 1; coisogenic strain|mutant strain: Rabep1
Proper citation: RRID:IMSR_JAX:039960 Copy
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