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http://drc.ucsf.edu/mouse-metabolism-core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 10,2024. Core which provides technical support for UCSF investigators to conduct metabolic studies using a 12-chambered Comprehensive Lab Animal Monitoring System (CLAMS), an EchoMRI, and Dual energy X-ray absorptiometry, which together allow measurement of food intake, water intake, motor activities, core temperature, and body composition in live mice. It also helps to identify emerging technologies that will enhance multiple research programs and coordinates the acquisition and maintenance of those facilities.

Proper citation: University of California San Francisco Diabetes Research Center Mouse Metabolism Core (RRID:SCR_015101) Copy   

•   Source: SciCrunch Registry

http://diabetesresearchcenter.dom.wustl.edu/translational-diagnostics-core/

Core provides range of assays for human and animal hormones, peptides, and metabolites related to metabolic disorders.

Proper citation: Washington University School of Medicine Diabetes Research Center Translational Diagnostics Core (RRID:SCR_015161) Copy   

•   Source: SciCrunch Registry

http://diabetesresearchcenter.dom.wustl.edu/transgenic-es-cell-core/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Core facility that provides services for efficient and cost-effective development of genetically altered mouse models to elucidate the pathogenesis of diabetes and related metabolic disorders.

Proper citation: Washington University School of Medicine Diabetes Research Center Transgenic and ES Cell Core (RRID:SCR_015141) Copy   

•   Source: SciCrunch Registry

https://www.derc.cuimc.columbia.edu/services/mouse-metabolic-function-and-phenotyping-core

Core that provides services that facilitate the efficient characterization of mouse models of diabetes and its complications: NMR Body Composition Analysis, Whole Body Metabolic Assessment (chamber calorimetry with motion detection), Metabolic Clamps, Gastric Infusion/Feeding and Thermogenic Phenotyping.

Proper citation: Columbia Diabetes Research Center Mouse Metabolic Function and Phenotyping Core Facility (RRID:SCR_015082) Copy   

•   Source: SciCrunch Registry

http://drtc.bsd.uchicago.edu/islet-cell-biology-core-about/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Core which provides services and hands-on training in the isolation and functional characterization of pancreatic islets from normal and diabetic humans and mice. It also maintains a repository of insulinoma cell lines for distribution. It puts emphasis on facilitating studies of primary islet cells and it has developed many unique tools and techniques for carrying such studies including novel animals models, biophysical methods and a library of adenovirus-based expression constructs for studying beta-cell function.

Proper citation: University of Chicago Diabetes Research and Training Center Islet Cell Biology Core (RRID:SCR_015132) Copy   

•   Source: SciCrunch Registry

http://depts.washington.edu/diabetes/viral-vector-and-transgenic-mouse/

Core facility that provides Diabetes Research Center affiliates with vectors necessary to overexpress, knockdown, knockout, or alter expression of RNAs and proteins of interest in cultured cells, isolated tissues, and animals.

Proper citation: University of Washington Diabetes Research Center Vector and Transgenic Mouse Core (RRID:SCR_015130) Copy   

•   Source: SciCrunch Registry

http://www.massgeneral.org/csibd/cores/genetic.aspx

Core whose services include breeding and maintenance of mutant mouse stocks, characterization of murine models, bone marrow transfers and adoptive T cell transfers, in vivo tracking of fluorescently labeled bacteria and cells, and whole body imaging of bioluminescent and fluorescent signals.

Proper citation: Center for the Study of Inflammatory Bowel Disease Genetic Animal Models Core (RRID:SCR_015238) Copy   

•   Source: SciCrunch Registry

http://obriencenter.yale.edu/mousecelllines.aspx

Core provides services to generate unique in vivo mouse models and kidney specific cell lines.

Proper citation: George M. O'Brien Kidney Center at Yale Mouse Genetics and Cell Line Core (RRID:SCR_015299) Copy   

•   Source: SciCrunch Registry

https://ddrcc.wustl.edu/scientific-cores/murine-models-gnotobiotics-core/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 15,2026. Core facility that provides advice and technical services to DDRCC investigators that include production of transgenic and chimeric mice, derivation of speed congenics and assisted reproduction services for maintaining pedigrees via the Mouse Genetics Core, as well as gnotobiotic mouse provision, colonization and rederivation.

Proper citation: Washington University Digestive Diseases Research Core Center Murine Models and Gnotobiotics Core (RRID:SCR_015260) Copy   

•   Source: SciCrunch Registry

http://livercenter.yale.edu/core-facilities/cellular-molecular-physiology-core-facility.aspx

Core facility that provides technical expertise, equipment and personnel to Liver Center Investigators who wish to work with animal models of liver disease, isolated liver cells, or gene expression in liver tissue. The Cell Isolation sub-core isolates hepatocytes and non-parenchymal liver cells primarily from rat and mouse, while the Molecular Biology sub-core provides equipment and expertise to Liver Center members in a centralized facility.

Proper citation: Yale Liver Center Cellular and Molecular Physiology Core (RRID:SCR_015258) Copy   

•   Source: SciCrunch Registry

http://animalcare.umich.edu/business-services/germ-free-mouse-facility

Core that provides services to the University of Michigan community and can also ship germ-free mice to locations worldwide. Its projects include studies investigating inflammatory bowel disease and cancer, host microbiome interactions, infectious disease pathogenesis, and mammalian and bacterial metabolism.

Proper citation: MMPC-University of Michigan Medical School Animal Care and Germ-Free Mouse Core (RRID:SCR_015344) Copy   

•   Source: SciCrunch Registry

http://medicine.yale.edu/labmed/ycceh/cores/core_d/index.aspx

Core facility which provides expertise, technical assistance, and mice for human-into-mouse xenotransplantation studies. Mouse models include MITRG-SKI (KnockIn) mice that express human cytokines and huSIRPa from the endogenous murine loci in the Rag-/- IL-2Ry -/- background. It also offers training and technical assistance in the study of hematopoiesis and benign hematologic questions in mice.

Proper citation: Yale Cooperative Center of Excellence in Hematology Animal Modeling Core (RRID:SCR_015349) Copy   

•   Source: SciCrunch Registry

http://zfrhmaps.tch.harvard.edu/cemh/CoreC.htm

Core facility for basic and translational stem cell research. The core's areas of expertise include human pluripotent stem cell biology, cGMP cell manufacturing, reprogramming, genome editing, genotyping, laboratory automation, chemical screening, and imaging/image analysis.

Proper citation: Boston Children's Hospital Center of Excellence in Molecular Hematology Stem Cell Engineering and Analysis Core (RRID:SCR_015352) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/resource/view/id/10800/community_id/1418

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 6th,2023. Core whose objective is to provide investigators at Vanderbilt and outside institutions a means to accurately assess cardiovascular phenotypes in mouse models of diabetes and metabolic disease. The CPC uses validated approaches and state-of-the-art instrumentation that allow for sensitive screening of phenotypic variations.

Proper citation: MMPC-Vanderbilt University School of Medicine Cardiovascular Pathophysiology Core (RRID:SCR_015353) Copy   

•   Source: SciCrunch Registry

https://www.med.unc.edu/marsicolunginstitute/core-facilities/mousemodelscore

Core that provides support and expertise for mouse colony maintenance, breeding strategies, mouse lung phenotyping protocols, and submission of live-animal applications to maintain compliance with IACUC guidelines.

Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Mouse Models Core (RRID:SCR_015389) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/resource/view/id/10822/community_id/1418

Core that ensures the health and welfare of mouse models by assuring that mice admitted to the MMPC meet defined health criteria and that post-quarantine protocol assignment. It diagnoses disease and identifies unique metabolic or cardiovascular phenotypes of mice through interaction with the Comparative Pathology Subcore.

Proper citation: MMPC-Vanderbilt University School of Medicine Animal Health and Welfare Core (RRID:SCR_015380) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/cysticfibrosis/about/animal-core

Core that assists in mouse line generation by both oocyte micro-injection and by embryonic stem cell gene targeting technologies. It also establishes breeding colonies of cystic fibrosis mice, and genotypes and provides these to UAB investigators and furnishes electrophysiology tests of CFTR activation, including murine nasal potential difference assays and intestinal short circuit current measurements.

Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Cystic Fibrosis Animal Models Core (RRID:SCR_015396) Copy   

•   Source: SciCrunch Registry

https://nyonrc.cumc.columbia.edu/content/molecular-biologymolecular-genetics-core

Core whose goal is to assist investigators in applying the tools and technologies of molecular genetics and genomics to elucidate the molecular-genetic bases of obesity and its comorbidities. Its services include consultation on study design, analysis, and applicable molecular biological techniques and developing and making research tools and reagents.

Proper citation: New York Obesity Nutrition Research Center Molecular Biology and Molecular Genetics Core (RRID:SCR_015436) Copy   

•   Source: SciCrunch Registry

http://www.mmpc.org/shared/showCenterCore.aspx?id=30

Core that provides investigators with services to accurately measure the major components of energy balance in their mouse models and tests that allow investigators to examine physiological factors that may influence food intake or energy expenditure.

Proper citation: MMPC-University of California Davis Energy Balance Exercise and Behavior Core (RRID:SCR_015364) Copy   

•   Source: SciCrunch Registry

http://www.umassmed.edu/umpc/cores/metabolism/

Core that conducts specialized and non-invasive metabolic experiments to measure insulin sensitivity, glucose/lipid/protein metabolism, pancreatic beta-cell function, body composition and energy balance. Its services include access to hyperglycemic clamps to assess insulin secretion and pancreatic beta cell function in awake mice and exercise studiesl with acute, chronic endurance, and exhaustive exercise protocols and using in-house cage wheels.

Proper citation: MMPC-University of Massachusetts Medical School Metabolism Core (RRID:SCR_015369) Copy   

•   Source: SciCrunch Registry