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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
A community-based data facility to support, sustain, and advance the geosciences by providing data services for observational solid earth data from the Ocean, Earth, and Polar Sciences. IEDA systems enable these data to be discovered and reused by a diverse community now and in the future. Data services include data access, data analysis, data compliance, data publication, DOI search, and web services. Desktop apps GeoMapApp and Virtual Ocean are available to explore, visualize and analyze your own data within the context of hundreds of other earth science data from around the world. IEDA is a partnership between EarthChem and the Marine Geoscience Data System (MGDS). EarthChem and MGDS systems include the geochemical databases PetDB and SedDB, the geochemistry data network EarthChem, the Ridge2000 and MARGINS Data Portals, the Academic Seismic Portal field data collection, the Antarctic and Southern Ocean Data System, the Global Multi Resolution Topography synthesis, and the System for Earth Sample Registration SESAR.
Proper citation: Integrated Earth Data Applications (RRID:SCR_006739) Copy
Platform for Traumatic Brain Injury relevant data. System was developed to share data across entire TBI research field and to facilitate collaboration between laboratories and interconnectivity between informatics platforms. FITBIR implements interagency Common Data Elements for TBI research and provides tools and resources to extend data dictionary. Established submission strategy to ensure high quality and to provide maximum benefit to investigators. Qualified researchers can request access to data stored in FITBIR and/or data stored at federated repositories.
Proper citation: Federal Interagency Traumatic Brain Injury Research Informatics System (RRID:SCR_006856) Copy
http://www.nida.nih.gov/mediaguide/index.html
The latest findings on the science of drug abuse and addiction and commonly abused drugs, and lists resources for more information. They are committed to bringing timely, factual information on addiction and treatment to the press and public. NIDA''s Public Information and Liaison Branch (PILB) is part of NIDA''s Office of Science Policy and Communications. Linking scientists, the scientific community, and the media, PILB supports the rapid dissemination of research information to inform policy and to improve practice. NIDA''s goal is to ensure that science - not ideology or anecdote - forms the foundation of public information on drug abuse and addiction. NIDAs online MEDIA GUIDE provides answers on how to find what you need to know about drug abuse and addiction, including information on the basics (The Science of Drug Abuse and Addiction and Commonly Abused Drugs), resources (Where to Find Nationwide Trends and Statistics, NIDA Resources, and Other Government Web Sites for Health and Science Information), NIDAs history and background, a glossary and relevant contact information. NIDA is pleased to offer this guide to the important findings that are emerging as a result of research on addiction and its treatment. NIDA, part of the National Institutes of Health under the U.S. Department of Health and Human Services, supports most of the world''s research on drug abuse and addiction, including basic and behavioral science research that addresses fundamental and essential questions relevant to drug abuse, ranging from its causes and consequences to its treatment and prevention. The purpose of this guide is to give journalists fast and user-friendly access to the latest scientific information but it is useful for anyone interested in how to access accurate information about drug abuse and addiction. In more than three decades as a researcher, I have seen the impact that science and health journalists have had in bringing scientific research to the public. It is through information that Americans gain hope and understanding. I have come to know many of you over the years and remain committed to releasing scientific information as quickly as possible for rapid dissemination to the public. Please keep this guide nearby as a useful tool and let us know how NIDA''s public liaison staff can help you reach your information and deadline needs. A PDF version is available for download.
Proper citation: National Institute on Drug Abuse Media Guide (RRID:SCR_006850) Copy
http://www.niaid.nih.gov/topics/transplant/research/Pages/fundedBasics.aspx#NHPTCSP
Cooperative program for research on nonhuman primate models of kidney, islet, heart, and lung transplantation evaluating the safety and efficacy of existing and new treatment regimens that promote the immune system''''s acceptance of a transplant and to understand why the immune system either rejects or does not reject a transplant. This program bridges the critical gap between small-animal research and human clinical trials. The program supports research into the immunological mechanisms of tolerance induction and development of surrogate markers for the induction, maintenance, and loss of tolerance.
Proper citation: Nonhuman Primate Transplantation Tolerance Cooperative Study Group (RRID:SCR_006847) Copy
http://painconsortium.nih.gov/
The NIH Pain Consortium was established to enhance pain research and promote collaboration among researchers across the many NIH Institutes and Centers that have programs and activities addressing pain. To this end, the following goals have been identified for the Pain Consortium: * To develop a comprehensive and forward-thinking pain research agenda for the NIH - one that builds on what we have learned from our past efforts. * To identify key opportunities in pain research, particularly those that provide for multidisciplinary and trans-NIH participation. * To increase visibility for pain research - both within the NIH intramural and extramural communities, as well as outside the NIH. The latter audiences include our various pain advocacy and patient groups who have expressed their interests through scientific and legislative channels. * To pursue the pain research agenda through Public-Private partnerships, wherever applicable. This underscores a key dynamic that has been reinforced and encouraged through the Roadmap process.
Proper citation: NIH Pain Consortium (RRID:SCR_006767) Copy
http://inparanoid.sbc.su.se/cgi-bin/index.cgi
Collection of pairwise comparisons between 100 whole genomes generated by a fully automatic method for finding orthologs and in-paralogs between TWO species. Ortholog clusters in the InParanoid are seeded with a two-way best pairwise match, after which an algorithm for adding in-paralogs is applied. The method bypasses multiple alignments and phylogenetic trees, which can be slow and error-prone steps in classical ortholog detection. Still, it robustly detects complex orthologous relationships and assigns confidence values for in-paralogs. The original data sets can be downloaded.
Proper citation: InParanoid: Eukaryotic Ortholog Groups (RRID:SCR_006801) Copy
Professional networking site dedicated to those working, studying, or simply interested in the science of the brain. Those with personal and professional interests in neuroscience, neurology, psychology, and all related areas -- those studying neural activities in invertebrates up to the human brain, including brain-like systems and networks are welcome. The NeuroNetwork was built to allow students and researchers to find and interact with each other in a professional environment. You may create searchable profiles with your research interests; start a blog; upload poster presentations and videos; post and search job listings; form a virtual group based on your interests, geographical location, etc.; and view, post, and RSVP to upcoming meetings. And don''t just create a profile for yourself -- create one for your organization, institute, society, or even your lab as well.
Proper citation: NeuroNetwork (RRID:SCR_006761) Copy
Software to determine most stable reference (housekeeping) genes from set of tested candidate reference genes in given sample panel. From this, gene expression normalization factor can be calculated for each sample based geometric mean of user-defined number of reference genes.
Proper citation: geNORM (RRID:SCR_006763) Copy
http://platform.invbrain.neuroinf.jp/
Database of information on nervous systems and behavior of various species of invertebrates and a large body of ancillary material to promote the use of invertebrate systems in research and education and facilitate information transfer to engineers that are looking for mechanisms that may be useful to solve a wide range of technological problems. The database is linked to explanations of the contents to allow users to familiarize themselves with the data and the context in which they were obtained. The platform has four entrance points tailored to different target user groups. The first entrance point is designed for users that are interested in using invertebrates for research purposes, in particular in the field of neuroscience, to assist them in initiating research projects. This includes databases of sensory systems, brains, and behavior of invertebrates, especially insects. The databases contain sensory organ structure and function, photographs and movies documenting insect behavior, data acquisition equipment and other instrumentation, software, material for eduction, and bibliography. A second entrance point is available for those that are concerned with implementations of design principles of invertebrate nervous systems and behavior in industrial applications. The third portal is destined for providing quick access for instructors that intend to use invertebrates for educational purposes and the remaining entrance point facilitates obtaining general comparative information on sensory and central nervous systems and behavior of invertebrates.
Proper citation: Invertebrate Brain Platform (RRID:SCR_006764) Copy
http://neuroade.christakou.org/
At neuroade, a Cognitive Neuroscience Laboratory, we study change in brain and behavior across multiple time-scales. Researchers in the lab combine a variety of methodologies to answer specific questions about typical and atypical behavior and development. We use functional magnetic resonance imaging (fMRI), peripheral psychophysiology (such as skin conductance responses), behavioral testing, genotyping analysis, and computational modeling. Most of our work takes place at the Centre for Integrative Neuroscience and Neurodynamics (CINN), and we all live in the Department of Psychology at the University of Reading. Our research is divided into several distinct yet highly interlinked themes, all converging in their application to understanding psychopathology -- summarised here in no particular order: * Decision-making and the Evaluation of Decision Outcomes * Dimensions of Impulsivity as a Foraging Strategy * Adolescent Development * Computational Modeling Probes of Individual Differences
Proper citation: neuroade (RRID:SCR_006758) Copy
http://diabetes.niddk.nih.gov/dm/pubs/america/
A compilation and assessment of epidemiologic, public health, and clinical data on diabetes and its complications in the United States. Published by the National Diabetes Data Group of the National Institute of Diabetes and Digestive and Kidney Diseases, the book contains 36 chapters organized in five areas: * the descriptive epidemiology of diabetes in the United States based on national surveys and community-based studies, including prevalence, incidence, sociodemographic and metabolic characteristics, risk factors for developing diabetes, and mortality * the myriad complications that affect patients with diabetes * characteristics of therapy and medical care for diabetes * economic aspects, including health insurance and health care costs * diabetes in special populations, including African Americans, Hispanics, Asian and Pacific Islanders, Native Americans, and pregnant women. Diabetes in America, 2nd Edition, has been designed to serve as a reliable scientific resource for assessing the scope and impact of diabetes and its complications, determining health policy and priorities in diabetes, and identifying areas of need in research. The intended audience includes health policy makers at the local and Federal levels who need a sound quantitative base of knowledge to use in decision making; clinicians who need to know the probability that their patients will develop diabetes and the prognosis of the disease for complications and premature mortality; persons with diabetes and their families who need sound information on which to make decisions about their life with diabetes; and the research community which needs to identify areas where important scientific knowledge is lacking.
Proper citation: Diabetes in America (RRID:SCR_006754) Copy
http://www.aids.gov/podcast/podcast-gallery/
Podcasts from AIDS.gov, featuring information from the Federal government about HIV/AIDS prevention, testing, research, treatment, and using new media in response to HIV/AIDS. Categories include: Basic HIV information, New Media, Federal Programs and Policies, HIV/AIDS Awareness Days, and Real Stories.
Proper citation: AIDS.gov Podcast (RRID:SCR_006750) Copy
http://watson.nci.nih.gov/bioc_mirror/packages/2.11/bioc/html/EDASeq.html
Software for numerical and graphical summaries of RNA-Seq read data. Within-lane normalization procedures to adjust for GC-content effect (or other gene-level effects) on read counts: loess robust local regression, global-scaling, and full-quantile normalization (Risso et al., 2011). Between-lane normalization procedures to adjust for distributional differences between lanes (e.g., sequencing depth): global-scaling and full-quantile normalization (Bullard et al., 2010)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: EDASeq (RRID:SCR_006751) Copy
http://sourceforge.net/projects/polgui/
An interface between MATLAB and the Polhemus Fastrak digitizer used to digitize fiducial locations and scalp EEG electrode locations. There are 5 versions all of which work under MATLAB R14 (on both linux and windows platforms), # polgui_ver1_r14 : works with 1 receiver (stylus pen) # polgui_ver2_r14 : works with 2 receivers (including the pen) # polgui_ver3_r14 : works with 3 receivers(including the pen) # polgui_ver4_r14 : works with 4 receivers (including the pen) # polgui_ver5_r14 : Generic version which works with 1/2/3/4 receivers (WARNING: Ver 5 might be buggy; not fully tested) Requirements: MATLAB R14 (Linux/Windows)
Proper citation: POLGUI - Matlab Polhemus Interface (RRID:SCR_006752) Copy
http://www.genomesunzipped.org/
A group blog providing expert, independent commentary on the personal genomics industry. The goal of the project is to provide genetic testing consumers with independent and informed analysis of developments in the field of genetics and the genetic testing industry. Members of Genomes Unzipped include active researchers in various fields of genetics, as well as specialists in the legal and public health issues surrounding new genomic technologies. Many of us have also been extensively involved in public communication about genetics. Members of the group have had their DNA tested with a variety of products. We have released all of these genetic data openly to the public, both as raw data and in a custom genome browser. As the project proceeds we plan to obtain more genetic tests ����?? up to and including whole genome sequencing ����?? and to continue to release these data to the world. The group is also performing analyses of our own raw genetic data to illustrate fundamental concepts in genetics, using software written both by group members and other collaborators; and we����??ll be releasing the code for that software in our new code repository. As the project expands, we����??ll be looking to add data from other volunteers to the project, as well as to collaborate with other ����??genome hackers����?? on the development of new tools for exploring genetic data.
Proper citation: Genomes Unzipped (RRID:SCR_006870) Copy
http://www.physionet.org/physiotools/
Growing library of software for physiologic signal processing and analysis, detection of physiologically significant events using both classical techniques and novel methods based on statistical physics and nonlinear dynamics, interactive display and characterization of signals, creation of new databases, simulation of physiologic and other signals, quantitative evaluation and comparison of analysis methods, and analysis of nonequilibrium and nonstationary processes. A unifying theme of the research projects that contribute software to PhysioToolkit is the extraction of hidden information from biomedical signals, information that may have diagnostic or prognostic value in medicine, or explanatory or predictive power in basic research. Contributions of software to PhysioToolkit are welcome, http://physionet.org/guidelines.shtml#software-contributions
Proper citation: PhysioToolkit (RRID:SCR_006868) Copy
http://www.molecularimaging.vcu.edu/
The Center for Molecular Imaging integrates molecular imaging and molecular medicine with systems biology approaches to understand disease complexity, promising to provide predictive, preventative and personalized medicine that will transform health care. The multi-modality molecular imaging program is composed of individual but overlapping research themes with specific projects under each theme. As all projects are underpinned by methodology development in the chemistry, biology, physics and bioengineering of imaging, there is always a strong overlap and cross feed in terms of methods and assays. The research themes include: * Biomarker pharmacodynamic imaging of metabolism, proliferation, cell death and vascular perfusion * Molecular genetic imaging in developing multi-modal reporter gene-based probes * Molecular imaging of angiogenesis and its relation to tumor hypoxia * Multi-modal nanoparticle probes for drug delivery and molecular imaging, including cell and immune-based therapies * Radiolabeled drug pharmacokinetics and studies of drug discovery and structural biology using molecular imaging strategies * Development of nanotechnology molecular imaging systems * Imaging proteomic mass spectrometry * Molecular imaging and molecular pathology diagnostic research The Center for Molecular Imaging fosters collaborative research, bringing together the advances being made in technology-driven research such as bioengineering, chemical genomics and nanotechnology with biomedical research groups studying cell and molecular biology and radiobiology, biologically targeted therapeutics, immuno-based mechanisms, and drug and biomarker discovery. The aim is to develop and validate multi-modality molecular imaging tools that will facilitate the advancement of translational medicine and clinical science research in oncology and neuroscience as well as other clinical research areas. The center is equipped with laboratories for radiochemistry, analytical chemistry, molecular biology, nanotechnology and animal imaging, as well as a dedicated facility for translational clinical imaging. Imaging technologies within the center include Positron Emission Tomography/Computed Tomography (preclinical and clinical), Single Photon Emission Computed Tomography, optical imaging, autoradiography and multi-modality nanotechnology imaging. Molecular probe developments underpin the biological and biomedical research conducted using the above modalities.
Proper citation: Virginia Commonwealth University Medical Center, Center for Molecular Imaging (RRID:SCR_006869) Copy
http://www.microbeworld.org/index.php?option=com_content&view=category&layout=blog&id=99&Itemid=259
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 4th,2023. This Week in Parasitism (TWiP) is a podcast about eukaryotic parasites hosted by Vincent Racaniello and Dick Despommier. Following in the path of their successful podcast ''This Week in Virology'' (TWiV), they strive for an informal yet informative conversation about parasites which is accessible to everyone, no matter what their science background. As science Professors at Columbia University, they have spent their entire academic careers directing research laboratories focused on parasites (Dick) and viruses (Vincent). Their enthusiasm for teaching inspired them to reach beyond the classroom with new media. TWiP is for everyone who wants to learn about parasites in a relaxing way. Music used on TWiP is composed and performed by Ronald Jenkees and used with permission.
Proper citation: TWiP - This Week in Parasitism (RRID:SCR_006788) Copy
http://dally.nimh.nih.gov/matoff/matoff.html
An interactive analysis program that searches neurophysiological data and plots the results. MatOFF was developed especially for dealing with the complexities common to behavioral neurophysiological experiments. It runs under Windows 2000 or XP and relies on MATLAB version R11.1 (or above) for all operations. MatOFF searches a data file to locate and plot epochs (trials) of special interest to the investigator. Appropriate input data files have time-stamped event codes, usually including neuron action potential firing events (spikes), and digitized analog data. The user specifies a list of event code numbers that uniquely identify a sequence of events. MatOFF uses this sequence to search the raw data file, select the epochs that meet the criteria, time-shift the trials to align them on a common event, order the epochs based on user-selected criteria, and plot the results based on a collection of page formatting specifications. MatOFF will also save extracted data and some statistics to disk. Features: * Powerful, interactive searching tools for locating relevant experimental events * Compatible with Cortex data acquisition program * Compatible with Plexon data acquisition system * Flexible, publication-quality graphical display and printing * Comprehensive scripting language * Supports learning and other dynamic behavior * Integrated interface to MATLAB functions * Automatic alignment of trial data and generation of histograms * Large variety of options for selecting and ordering trial data * Descriptive and non-parametric statistics * XY analog displays * Data export with flexible format control * Up to 72 plots per page * Display templates can be saved and reloaded * Free for public or private use * Adaptable to almost any data file format
Proper citation: MatOFF (RRID:SCR_006821) Copy
http://sourceforge.net/projects/bmdexpress/
Bioinformatics tool used to analyze microarray dose-response data. The analysis provides benchmark dose estimates at which different cellular processes are altered in toxicogenomic experiments.
Proper citation: BMDExpress (RRID:SCR_006823) Copy
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