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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioconductor.org/packages/release/bioc/html/snm.html
Software package that uses a modeling strategy especially designed for normalizing high-throughput genomic data. The premise is that your data is a function of study-specific variables which are either biological variables that represent the target of the statistical analysis, or adjustment variables that represent factors arising from the experimental or biological setting the data is drawn from. The SNM approach aims to simultaneously model all study-specific variables in order to more accurately characterize the biological or clinical variables of interest.
Proper citation: SNM (RRID:SCR_001299) Copy
https://rdrr.io/bioc/betr/man/betr.html#heading-0
Software package that implements the Bayesian Estimation of Temporal Regulation algorithm to identify differentially expressed genes in microarray time-course data.
Proper citation: betr (RRID:SCR_001332) Copy
A Swiss global health-care company that operates under two divisions: Pharmaceuticals and Diagnostics.
Proper citation: Roche (RRID:SCR_001326) Copy
https://bioconductor.org/packages//2.11/bioc/html/gprege.html
Software R package for Gaussian Process Ranking and Estimation of Gene Expression time-series. The software fits two Gaussian processes (GPs) with an radial basis function (RBF) (+ noise diagonal) kernel on each profile. One GP kernel is initialized wih a short lengthscale hyperparameter, signal variance as the observed variance and a zero noise variance. It is optimized via scaled conjugate gradients (netlab). A second GP has fixed hyperparameters: zero inverse-width, zero signal variance and noise variance as the observed variance. The log-ratio of marginal likelihoods of the two hypotheses acts as a score of differential expression for the profile. Comparison via receiver operating characteristic curves (ROC curves) is performed against Bayesian hierarchical model for the analysis of time-series (BATS) (Angelini et.al, 2007).
Proper citation: gprege (RRID:SCR_001324) Copy
https://www.bioconductor.org/packages//2.13/bioc/html/waveTiling.html
Software package to conduct transcriptome analysis for tiling arrays based on fast wavelet-based functional models.
Proper citation: waveTiling (RRID:SCR_001322) Copy
http://sourceforge.net/projects/kanalyze/
A Java toolkit designed to convert DNA and RNA sequences into k-mers.
Proper citation: KAnalyze (RRID:SCR_001323) Copy
http://www.bioconductor.org/packages/release/bioc/html/AffyExpress.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software package for quality assessment and to identify differentially expressed genes in the Affymetrix gene expression data.
Proper citation: AffyExpress (RRID:SCR_001321) Copy
Biomedical technology research center that creates optimal facilities and environments and support for macromolecular structure determination by synchrotron X-ray diffraction at the National Synchrotron Light Source for the benefit of outside and in-house investigators. The PXRR innovates new access modes such as Mail-in crystallography, builds new facilities, currently on the X25 undulator, advances automation, develops remote participation software, collaborates with outside groups, teaches novice users, and supports vising investigators with 7-day, 20-hours staff coverage.
Proper citation: Macromolecular Crystallography Research Resource (RRID:SCR_001442) Copy
https://medicine.yale.edu/keck/nida/yped/
Open source system for storage, retrieval, and integrated analysis of large amounts of data from high throughput proteomic technologies. YPED currently handles LCMS, MudPIT, ICAT, iTRAQ, SILAC, 2D Gel and DIGE. The repository contains data sets which have been released for public viewing and downloading by the responsible Primary Investigators. It includes proteomic data generated by the Yale NIDA Neuroproteomics Center (http://medicine.yale.edu/keck/nida/index.aspx). Sample descriptions are compatible with the evolving MIAPE standards.
Proper citation: YPED (RRID:SCR_001436) Copy
http://www.anxietyaustralia.com.au/
Anxiety Treatment Australia provides information about anxiety disorders, the treatment options, psychologists around Australia who treat anxiety disorders, group therapy & workshops, support groups, articles, resources and links to other sites. Sponsors: his website is brought to you by Catherine Madigan, a Melbourne Clinical Psychologist who specializes in the treatment of Anxiety Disorders (ABN 51 109 368 630).
Proper citation: Anxiety Treatment Australia: Anxiety Disorder Help, Information and Psychologist List (RRID:SCR_001434) Copy
http://www.bioconductor.org/packages/release/bioc/html/beadarray.html
Software package to read bead-level data (raw TIFFs and text files) output by BeadScan as well as bead-summary data from BeadStudio. Methods for quality assessment and low-level analysis are provided.
Proper citation: beadarray (RRID:SCR_001314) Copy
http://www.bioconductor.org/packages/release/bioc/html/arrayMvout.html
Software package that supports the application of diverse quality metrics to AffyBatch instances, summarizing these metrics via PCA, and then performing parametric outlier detection on the PCs to identify aberrant arrays with a fixed Type I error rate.
Proper citation: arrayMvout (RRID:SCR_001317) Copy
http://www.nitrc.org/projects/philips_users/
Communnity project to help support the efforts of investigators using Philips Healthcare systems. This clearingsite helps users find forums, mailinglists, etc. that support this community. If you have suggestions for inclusion, let the project admin know!
Proper citation: Philips Users Community (RRID:SCR_001438) Copy
https://www.bioconductor.org/packages//2.7/bioc/html/affyQCReport.html
Software package to create a QC report for an AffyBatch object. The report is intended to allow the user to quickly assess the quality of a set of arrays in an AffyBatch object.
Proper citation: affyQCReport (RRID:SCR_001318) Copy
https://www.bioconductor.org/packages//2.12/bioc/html/maigesPack.html
Software package that uses functions to handle and analyze cDNA microarray data.
Proper citation: maigesPack (RRID:SCR_001351) Copy
http://www.bioconductor.org/packages/release/bioc/html/mdqc.html
A multivariate quality assessment software for microarrays based on quality control (QC) reports. The Mahalanobis distance of an array's quality attributes is used to measure the similarity of the quality of that array against the quality of the other arrays. Then, arrays with unusually high distances can be flagged as potentially low-quality.
Proper citation: MDQC (RRID:SCR_001352) Copy
http://www.bioconductor.org/packages/release/bioc/html/macat.html
Software library that contains functions to investigate links between differential gene expression and the chromosomal localization of the genes. It is motivated by the common observation of phenomena involving large chromosomal regions in tumor cells. MACAT is the implementation of a statistical approach for identifying significantly differentially expressed chromosome regions.
Proper citation: MACAT (RRID:SCR_001350) Copy
http://www.bioconductor.org/packages/release/bioc/html/nnNorm.html
Software package that allows to detect and correct for spatial and intensity biases with two-channel microarray data. The normalization method implemented in this package is based on robust neural networks fitting.
Proper citation: nnNorm (RRID:SCR_001354) Copy
http://www.bioconductor.org/packages/release/bioc/html/maCorrPlot.html
Software that graphically displays correlation in microarray data that is due to insufficient normalization.
Proper citation: maCorrPlot (RRID:SCR_001348) Copy
http://www.bioconductor.org/packages/release/bioc/html/lapmix.html
Software to identify differentially expressed genes. A hierarchical Bayesian approach is used, and the hyperparameters are estimated using empirical Bayes.
Proper citation: lapmix (RRID:SCR_001347) Copy
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