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Provides comprehensive solution characterization of macromolecules or macromolecular interactions and assemblies. This includes description of stoichiometry, size composition, cargo loading.Core is equipped with analytical ultracentrifuges featuring multi-wavelength UV-visible detection, as well as Rayleigh interference optics and fluorescence emission detection for fluorescent tags with 488 nm excitation.
Proper citation: University of Lethbridge Canadian Center for Hydrodynamics Core Facility (RRID:SCR_023791) Copy
https://med.miami.edu/research/cores/biomarker-and-immunoassay-laboratory
Provides biomarker testing for human clinilcal research studies across multiple disciplines.Provides expertise with chemistry, special chemistry, radioimmunoassay, nephelometric and ELISA and multiplexing assay methods utilizing automated and manual procedures. Laboratory has Clinical Laboratory Improvement Act certification and follows guidelines established by CLIA for quality control and proficiency testing to ensure results. Core coordinates proper pre-analytical sample collection and processing procedures with project leaders; performs biochemical assays on samples submitted to the laboratory by investigators in manner that assures strict quality control both within and between assay runs; reports results to project staff in timely fashion; makes available expertise and technical assistance for establishing and validating new methodologies to support University of Miami investigators.
Proper citation: University of Miami Miller School of Medicine Biomarkers and Immunoassay Laboratory Core Facility (RRID:SCR_023705) Copy
https://www.heka.com/products/products_main.html#physiol_epc10multi
Electrophysiology patch clamp amplifier for collecting electrical signals from tissues and cells. Can be controlled via USB. Designed and manufactured by HEKA Elektronik.
Proper citation: Heka Elektronik: EPC 10 USB Patch Clamp Amplifier (RRID:SCR_018399) Copy
https://www.corelaboratory.abbott/us/en/offerings/brands/architect/architect-i1000SR
Immunoassay analyzer by Abbott for chemiluminescent microparticle immunoassay technology. Sample types include serum, plasma, whole blood, and urine.
Proper citation: Abbott: ARCHITECT i1000sr System (RRID:SCR_018371) Copy
https://www.beckmancoulter.com/products/immunoassay/dxi-800
Immunoassay analyzer that can run up to 400 tests per hour and has standardized test menus, assay protocols, instrument processes and reference ranges. Sample types include serum, plasma, urine, amniotic fluid, and whole blood.
Proper citation: Beckman Coulter: UniCel DxI 800 Access Immunoassay System (RRID:SCR_018370) Copy
https://diagnostics.roche.com/us/en/products/instruments/cobas-e-411.html
Fully automated analyzer for immunoassay analysis by Roche. Designed for in vitro assay determinations. Applications including anemia, bone, cardiac and tumor markers, critical care, fertility hormones, and infectious diseases. Available as rack or disk sample handling system.
Proper citation: Roche: cobas e 411 analyzer (RRID:SCR_018369) Copy
https://www.scientifica.uk.com/products/slicescope-pro-2000
Electrophysiology system for dual or single patch clamp recording with movable microscope. Consists of SliceScope microscope, motorised XY translation stage, fixed stage platform, and two Patchstar motorised micromanipulators. Manufactured by Scientifica LTD.
Proper citation: Scientifica: SliceScope Pro 2000 (RRID:SCR_018405) Copy
https://www.planmeca.com/cadcam/dental-scanning/planmeca-emerald/
Intraoral scanner for taking digital impressions.
Proper citation: Planmeca: Emerald Intraoral scanner (RRID:SCR_018404) Copy
https://www.e-lspi.com/labnet-spectrafuge-24d-digital-microcentrifuge-mini-centrifuge-c2400
Microcentrifuge with brushless drive that accelerates rotor to maximum speed of 13,300 rpm and 16,000 x g. Features precise digital microprocessor control. Speed knob sets speed in either rpm or g-force. Timer knob sets time parameter.
Proper citation: Labnet: C2400 Spectrafuge 24D Microcentrifuge (RRID:SCR_018588) Copy
https://www.labconco.com/product/refrigerated-centrivap-vacuum-concentrators/74
Refrigerated centrifugal concentrator that concentrates heat sensitive samples using centrifugal force, vacuum, and controlled temperature. Concentrator has heater and refrigeration systems have temperature range of negative 4 C to 100 C.
Proper citation: Labconco: CentriVap Refrigerated Centrifugal Concentrator (RRID:SCR_018587) Copy
Microplate reader with top and bottom read capability with dual monochromators for fluorescence intensity assays using multiple point well scanning. Temperature sensitive reactions are from ambient to 45 C. Measures fluorescence on variety of sample formats from 6 to 384 well microplates in endpoint, kinetic, spectral scan, and well-scan modes.
Proper citation: Molecular Devices: Gemini EM Microplate Reader (RRID:SCR_018584) Copy
Library preparation system that produces 16 sequencing ready libraries per run. There are steps in NeoPrep workflow run preparation, library card loading, and library collection.
Proper citation: Illumina: NeoPrep Library Preparation System (RRID:SCR_018583) Copy
https://www.konnis.com/products/instruments-for-sale/hamilton-starlet-liquid-handling-system/
Liquid handling robot with 8 channel pipetting arm, dual HEPA filter top, and 96 channel pipeting head with 1ml capacity. It can have tube racks, microplate racks, and 50mL temperature controlled tube rack.
Proper citation: Hamilton: StarPlus Automated Liquid Handler (RRID:SCR_018582) Copy
https://www.labx.com/product/applied-biosystems-3700
Automated capillary gel electrophoresis genetic analyzer that sequences up to 96 DNA templates per run and is used for PCR sequencing and short tandem repeat genotyping.
Proper citation: Thermo Fisher: Applied Biosystems: ABI 3700 Genetic Analyzer (RRID:SCR_018431) Copy
https://www.labx.com/product/applied-biosystems-3100
Benchtop capillary genetic analyzer multicolor fluorescence based DNA analysis system with 16 capillaries. It can process 96 or 384 well plates.
Proper citation: Thermo Fisher: Applied Biosystems: ABI 3100 Capillary Genetic Analyzer (RRID:SCR_018430) Copy
Isothermal titration calorimeter for label free, in solution, study of biomolecular interactions. It delivers measurement of binding parameters with minimum of 10 ug sample.
Proper citation: Malvern Panalytical: Microcal ITC 200 Isothermal Titration Calorimeter (RRID:SCR_018590) Copy
Benchtop manager cell sorter for cell isolation in automated workflows. Sorts cells directly from whole blood or bone marrow without density gradient centrifugation or erythrocyte lysis.
Proper citation: Miltenyi: AutoMACS Magnetic Cell Sorter (RRID:SCR_018596) Copy
https://ctac.mbi.ufl.edu/histology-self-serve/microm-cryostat/
Electronic microtome cryostat upright standing with open top working area that can cut temperature to negative 35 degrees Celsius. Equipped with automatic 24 hour defroster with interrupt key and handwheel brake.Provides protection for knife and specimen as it retracts specimen at the end of the cut. Motorized coarse feed system allows sample to be moved forward and backward.Two knife carriers are available. Standard knife carrier is for knives to be easily clamped in place and adjusted, and the disposable blade holder EC for high- and low-profile blades.
Proper citation: Microm: HM505E Cryostat (RRID:SCR_018595) Copy
Differential scanning calorimeter for study of samples in solution. It measures intramolecular stability of proteins, nucleic acids, oligomeric proteins, nucleic acid duplexes, lipid and detergent micellar system.
Proper citation: Malvern Panalytical: Microcal VPViewerTM Differential Scanning Calorimeter VP--DSC (RRID:SCR_018594) Copy
https://www.perkinelmer.com/Product/ht-labchip-gx-ii-touch-cls138160
LabChip GXII Touch is a protein characterization system that provides reproducible quantitation, molecular weight sizing and percent purity analysis of protein samples. Leveraging microfluidic electrophoretic separation technology, the LabChip GXII Touch system enables rapid characterization with minimal sample preparation setup and sample input volume.
Proper citation: Illumina: LabChip GXII Touch protein characterization system (RRID:SCR_018593) Copy
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