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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Core provides central hub to help leverage bioinformatics and data science methods in research projects. Services include Transcriptomics: bulk RNA-Seq, single-cell RNA-Seq, and spatial RNA-Seq; Genomics: SNP, structural variants (SV), and copy number variation (CNV) analyses; Regulatory genomics: ChIP-Seq, ATAC-Seq, CUT&RUN, and Hi-C; Functional genomics: CRISPR-based loss-of-function screens;Image and metadata analysis: AI/ML-based approaches including knowledge graphs. Offers training, education, collaboration, consultation,custom guidance on study design and analysis approaches. Provides classroom and custom training sessions on computational, data science, bioinformatics topics, tailored workshops for requested specialized topics. Offers technical infrastructure and support, computing resource optimization and facilitation, bioinformatics software deployment (conda environments and Docker containers), version control and reproducible science (Git repositories), data management support and submission to public repositories.
Proper citation: Koch Institute at MIT Data Science and Multimodal Integration Core Facility (RRID:SCR_017894) Copy
https://coreimmunology.ucsf.edu/services
Provides immunology assays, expert consultation, and education to UCSF and global research community. CIL specializes in developing immunology research tools, and initiating and stimulating innovative research projects to address emerging questions in immunologic diseases including HIV pathogenesis.Services include:Isolation of PBMC for staining, cell sorting, or viable cryopreservation;Isolation of mucosal mononuclear cells (MMC) from mucosal tissue biopsies;Immunomagnetic bead isolation of untouched cell populations for functional studies;Immunophenotyping of whole blood, PBMC, MMC and cerebrospinal fluid for: NK, B and T cells percentages, and their subsets, including maturation, trafficking, senescence, activation, in vivo proliferation and chemokine receptor expression;Flow cytometric functional assays, including NK cell function, antigen-specific CD4+ and CD8+ T cell cytokine expression, degranulation and proliferation;Evaluation of T cell signaling by phosflow using monoclonal antibodies specific for phosphorylated protein;Training and Support;Flow Cytometry Training Course;Three-hour lecture and lab course designed to cover basics of flow cytometry including:Fluorescence emission and detection,Fluidics,Operation,Panel design,Controls.
Proper citation: University of California at San Francisco Immunology Lab Core Facility (RRID:SCR_017906) Copy
Integrated healthcare biobank that operates under certified conditions and strict SOPs. Enables biomedical and translational researchers to perform their analyses using high quality biospecimens and data to generate reliable and reproducible research data. Core offers modular biobanking portfolio that can cover workflow from blood collection to storage, including all pre-analytical steps and their documentation. Offers spectrum of additional services ranging from DNA/RNA extraction and virtual microscopy to entire management of sample and data flow for national and international research consortia. Provides secure conventional and automated storage of samples at various temperatures as well as secure data management.
Proper citation: Charite University and Berlin Institute for Health Research Central Biobank Core Facility (RRID:SCR_023495) Copy
https://www.med.upenn.edu/ifi/cytofservicecenter.html
CyTOF�enables multi-parametric high-dimensional single�cell analysis�of more than 40 markers per cell, with�minimal background and compensation�issues.�Core�offers variety of�CyTOF-related services including�reagent distribution, consultation,�antibody conjugation, and data acquisition.�
Proper citation: University of Pennsylvania Perelman School of Medicine IFI CyTOF Service Center Core Facility (RRID:SCR_022410) Copy
BioBank supports researchers by providing centralized access to large number of annotated blood and tissue samples.
Proper citation: University of Pennsylvania Perelman School of Medicine Penn Medicine BioBank Core Facility (RRID:SCR_022415) Copy
https://pathology.med.upenn.edu/research/core-resources/tumor-tissue-biospecimen-bank
Centralized biorepository of human biosamples. TTAB is responsible for the collection, processing, and storage of human blood, fluid, and tissue at the University of Pennsylvania Health System. TTAB has a collection bench within Surgical Pathology Suite at Hospital of University of Pennsylvania (HUP).� Our collection bench sits adjacent to frozen section teams managing clinical sample collection and allowing for tight integration of tissue sample collection with clinical pathology teams.
Proper citation: University of Pennsylvania Perelman School of Medicine Tumor Tissue Biospecimen Bank Core Facility (RRID:SCR_022430) Copy
https://edspace.american.edu/openbehavior/project/automated-mouse-homecage-two-bottle-choice-test/
Project related to assessing preferences by mice among fluids in their homecages.Provided system includes homecage fitted apparatus for automated, photobeam based detection of licks in two bottle choice task. Used for automated mouse homecage two bottle choice test.
Proper citation: Automated mouse homecage two bottle choice test project (RRID:SCR_021457) Copy
https://edspace.american.edu/openbehavior/project/rad/
Project related to tracking and recording activity in rodent home cages.Provides device that utilizes passive infrared (PIR) sensor to detect movement in cages and logs data to microSD card. Device is wireless and battery powered, and can record data for about 3 weeks on charge.
Proper citation: Rodent Activity Detector project (RRID:SCR_021451) Copy
https://edspace.american.edu/openbehavior/project/homecage-2bottle-choice/
Project related to studies of liquid ingestive behaviors used in neuroscience to investigate reward related behavior, metabolism, and circadian biology. Provides automated home cage sipper device for monitoring liquid ingestive behavior in rodents developed by Washington University, St. Louis scientists. Homecage fitted apparatus for automated, photobeam based detection of licks in two bottle choice task.
Proper citation: Automated Home Cage Rodent Two bottle Choice Test project (RRID:SCR_021445) Copy
https://www.agilent.com/cs/library/brochures/5990-5596EN.pdf
Agilent 3100 OFFGEL Fractionator performs isoelectric focusing of proteins or peptides in immobilized pH gradient (IPG) gel strips.
Proper citation: Agilent: 3100 OFFGEL Fractionator (RRID:SCR_018433) Copy
https://www.microscopyu.com/museum/model-smz1500-stereomicroscope
SMZ1500 stereoscopic zoom microscope is system with apochromatic objectives, zoom ratio of 15 to 1, range of magnifications from 0.75x to 11.25x for total magnifying capability of 3.75x up to 540x, and is best for in depth imaging.Zoom knob allows to zoom from 1x to 11x at 1x-intervals without interrupting observations. Other facets include high eyepoint eyepieces with built-in diopter adjustments, wide field of view, and built-in aperture diaphragm for achieving optimal depth of focus and improved photomicrography.Provides options of either low eye-level viewing tube or tilting eyepiece tube, with or without eye-level risers. Three different diascopic stands with built-in power supplies may also be utilized with instrument, or standard stand that features low profile for increased clearance.
Proper citation: Nikon: SMZ1500 Zoom Stereoscope (RRID:SCR_018605) Copy
https://www.ttuhsc.edu/pharmacy/research/documents/Amnis-Imagestream-Manual.pdf
Bench top multispectral imaging flow cytometer designed for the acquisition of up to 12 channels of cellular imagery. It combines per cell information with statistical significance of sample sizes of standard flow cytometry.
Proper citation: Luminex: Amnis ImageStreamX Mk II System (RRID:SCR_018589) Copy
Airport security liquid explosive detection system LEDS screens all common container types with low false alarm rate.
Proper citation: Agilent: Cobalt Insight200M Aviation Security - Bottle Screener for Liquid, Aerosols & Gels (RRID:SCR_019490) Copy
https://www.agilent.com/en/products/dissolution/automated-systems/cary-8454-uv-dissolution-system
UV Dissolution System analyzes single and select multicomponent products using diode array technology.
Proper citation: Agilent: Cary 8454 UV Dissolution System (RRID:SCR_019494) Copy
High-Recovery Protein Column reduces or eliminates strong adsorption of proteins.
Proper citation: Agilent: mRP-C18 High-Recovery Protein Column (RRID:SCR_019518) Copy
Positive Pressure Manifold 96 Processor provides consistent gas flow for up to 96 cartridges in applications such as SPE and SLE.
Proper citation: Agilent: Positive Pressure Manifold 96 Processor (PPM-96) (RRID:SCR_019528) Copy
https://www.agilent.com/en/products/icp-ms/icp-ms-analyzers/iso-17294-water-analyzer
ICP-MS Water Analyzer streamlines steps taken to put ICP MS instrument in production and implement regulated water analysis.
Proper citation: Agilent: ISO 17294 ICP-MS Water Analyzer (RRID:SCR_019520) Copy
Roots Pumping System is used for optimum system integration and enables continuous operation and monitoring of vacuum systems.
Proper citation: Agilent: RPS-1401/301 Roots Pumping System (RRID:SCR_019535) Copy
Mobile Dry Helium Leak Detector uses mass spectrometer tuned to detect helium to locate and measure small leaks in enclosed devices or systems.
Proper citation: Agilent: HLD MD30 Mobile Dry Helium Leak Detector (RRID:SCR_019506) Copy
Benchtop genetic analyzer. Electrophoresis system for DNA and RNA sample quality control. It can be used for next generation sequencing or Biobank workflow.
Proper citation: Agilent: 4200 TapeStation System (RRID:SCR_018435) Copy
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