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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Provides diabetes researchers with access to novel human stem cell-derived in vitro cell models for investigating cellular and molecular features of both Type 1 and Type 2 diabetes. Recent progress in stem cell, organoid culture, gene editing and directed differentiation technologies has afforded opportunities to develop pre-clinical human models.Provides expertise, infrastructure and access to novel human model systems and technologies to DRC investigators. Provides expertise, resources and training in stem cell technologies together with quality control testing, validation standardization and authentication all model platforms and reagents.
Proper citation: University of Colorado Anschutz Medical Campus Diabetes Research Center Disease Modeling Core Facility (RRID:SCR_022905) Copy
Provides Cincinnati Children s Hospital Medical Center; Cincinnati; Ohio resources in confocal, wide-field, and spatial technique applications.
Proper citation: Cincinnati Children's Hospital Confocal Imaging Core Facility (RRID:SCR_022628) Copy
Core leverages current clinical research facilities and equipment available at Barbara Davis Center for Childhood Diabetes, UC AMC Clinical Translational Research Center, University of Colorado Hospital, Denver Veteran Administration Medical Center and Children Hospital Colorado.Core integrates diabetes research across these institutions through communication and distribution of resources available, and creates shared sample and data biobanks and recruiting database of mothers, infants, children, adolescents and adults with diabetes, diabetes risk and controls.
Proper citation: University of Colorado Anschutz Medical Campus Diabetes Research Center Clinical Resource Core Facility (RRID:SCR_022903) Copy
Research facility for studying paramagnetic centers by continuous wave and pulsed EPR techniques to obtain information on electronic, chemical, and geometric molecular structures.
Proper citation: University of Arizona Electron Paramagnetic Resonance Core Facility (RRID:SCR_022883) Copy
https://www.cincinnatichildrens.org/research/cores/pathology-core
Provides technical support for routine morphology based techniques. Pathologists are on hand to help guide projects, interpret results and collaborate on publications. Core personnel provide technical support for routine morphology based techniques including tissue processing and embedding, routine and special histochemical staining, immunohistochemistry, in situ hybridization, and electron microscopy.
Proper citation: Cincinnati Children's Hospital Pathology Research Core Facility (RRID:SCR_022637) Copy
https://www.cincinnatichildrens.org/research/cores/metabolomics
Provides all NMR related metabolomics services on human and animal cells, biopsies and body fluids.
Proper citation: Cincinnati Children's Hospital NMR based Metabolomics Core Facility (RRID:SCR_022636) Copy
Research on microbial agents, which cause lethal diseases in humans and for which effective drugs or preventive vaccines are not available, must be conducted by well-trained investigators in specially built, well-maintained laboratories. Core provides the triad of service, research and development, and education and training.
Proper citation: University of Hawaii at Manoa ABSL3/BSL3 Biocontaminant Core Facility (RRID:SCR_022878) Copy
https://www.cincinnatichildrens.org/research/cores/flow-cytometry
Shared resource lab for flow cytometry instrumentation, training, education and analyte measurement (ELISA, Luminex, IsoLight). New users need to be trained for their instrument of choice.
Proper citation: Cincinnati Children's Hospital Research Flow Cytometry Core Facility (RRID:SCR_022635) Copy
https://www.cincinnatichildrens.org/research/cores/pluripotent-stem-cell-facility
Supports all aspects of human pluripotent stem cell research, providing access to well characterized human embryonic stem cells and induced pluripotent stem cells for distribution to researchers. Consists of tissue culture facilities, access to microscopy and histology equipment, as well as equipment for cellular and molecular analysis of hESCs.
Proper citation: Cincinnati Children's Hospital Pluripotent Stem Cell Core Facility (RRID:SCR_022634) Copy
https://www.cincinnatichildrens.org/research/support/clinical-translational-research
Clinical research support center for investigators and industry sponsors.Provides support services, research tools, experienced research personnel, and facilities to conduct or facilitate pediatric and adult clinical research from identification and development of research opportunities to phase I through phase IV clinical research trials.
Proper citation: Cincinnati Children's Hospital Office for Clinical and Translational Research Core Facility (RRID:SCR_022633) Copy
Facility manufactures lentiviral and retroviral vectors in support of early phase clinical trials.Services include large scale GMP lentiviral and retroviral vector and small to mid scale GMP like manufactured products. Supports certification and stability studies.
Proper citation: Cincinnati Children's Hospital Vector Production Core Facility (RRID:SCR_022639) Copy
https://www.janelia.org/support-team/quantitative-genomics
Provides services to anything related to genomic analysis, such as RNAseq, genome sequencing, ATACseq etc, from experiment design all the way down to data analysis.Provides expert services for cell isolation, transcriptome and epigenetic profiling, and de novo genome assembly using next generation sequencing platforms from Illumina.
Proper citation: Howard Hughes Medical Institute at Janelia Research Campus Quantitative Genomics Core Facility (RRID:SCR_022694) Copy
Offers services to researchers looking for collaborators or contractors for their educational or training projects.Offers development tools and hosting services to educators creating their own online training resources.
Proper citation: Texas A and M University Center for Educational Technologies Core Facility (RRID:SCR_022691) Copy
https://www.chumontreal.qc.ca/crchum/plateformes-services/imagerie-cellulaire
Optical and fluorescence microscopy facility. Provided instruments include range of microscopes from regular brightfield microscopes to high performence LSM900- Airyscan confocal microscope. Provides Image Analysis with Imaris Full Spectrum and ClearDeconvolution software.
Proper citation: University of Montreal CRCHUM Cell Imaging Core Facility (RRID:SCR_022726) Copy
https://drexel.edu/core-facilities/facilities/cell-imaging/
Facility housed in purpose built imaging suites in Papadakis Integrated Sciences Building and in Bossone Research Center. Serves light microscopy needs of Drexel researchers and supports teaching missions of Biology and Biomedical Engineering curricula and provides service to users from local biotech companies.Provides facility, expertise, and education in advanced quantitative light microscopy.
Proper citation: Drexel University Cell Imaging Center Core Facility (RRID:SCR_022689) Copy
https://research.utexas.edu/cbrs/cores/cbb/
Provides support for students, postdoctoral fellows, and faculty interested in the use of computational approaches to solving biological problems. Our goal is to lower as much as possible the threshold to enter the -omics area of the life sciences.
Proper citation: University of Texas at Austin Computational Biology and Bioinformatics Core Facility (RRID:SCR_022688) Copy
https://www.umassmed.edu/scope/
Offers tools and expertise for quantitative microscopy techniques including super resolution imaging, multi photon intravital and live tissue imaging, confocal microscopy, and high speed time lapse imaging.Offers commercial and custom built microscopes, training and access to light microscopes, imaging services including whole slide scanning, MERFISH spatial transcriptomics, NanoString GeoMx DSP services, and image analysis support. Wet lab facilities, including cell culture, are also available at this BL2 facility. Imaging at BSL3 is available upon request.Offers remote imaging and data analysis sessions, including remote control of all instruments and workstations. All users are trained individually prior to use of the SCOPE equipment and workstations.
Proper citation: University of Massachusetts Medical School Sanderson Center for Optical Experimentation Core Facility (RRID:SCR_022721) Copy
https://ag.purdue.edu/department/arge/facilities-and-research/microscopy/index.html
Provides Purdue researchers access to electron microscopy instrumentation including scanning electron microscopes, small dual beams and transmission electron microscopes. Expert staff scientists help with training and project support.
Proper citation: Purdue Electron Microscopy Center (RRID:SCR_022687) Copy
https://www.purdue.edu/discoverypark/bioscience/facilities/core/metabolite/index.php
Provides technologies that enable both qualitative (defining all components of metabolome) and quantitative (determining differential concentrations of metabolites) metabolomics in complex biological systems.Provides sensitive mass spectrometry coupled with liquid chromatography and gas chromatography for precise sample analysis. Empowers researchers with new technologies, methods development, sample analysis, expert training, and consultation.
Proper citation: Purdue University West Lafayette Metabolite Profiling Core Facility (RRID:SCR_022728) Copy
https://bioimaging.dbi.udel.edu/flow-cytometry-core-2/
Facility, located at the University of Delaware Main campus (UD) in Newark, Delaware, provides flow cytometry and hematology services. Facility is equipped with 15-color FACSAria Fusion high-speed cell sorters,BD Rhapsody Express Cell Processing Unit,VetScan HM5c veterinary hematology analyzer, Nexcelom Cellometer Vision cell counter, Zeiss Axiovert 200 inverted fluorescent microscope,Thermo Shandon Cytospin 4 & a Beckman Spinchron DLX centrifuge,General Laboratory facilities for Mammalian Cell Culture and Sample preparation,Laminar flow BSL-2 biosafety cabinets, microscopes and centrifuges.
Proper citation: University of Delaware Flow Cytometry Core Facility (RRID:SCR_022861) Copy
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