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http://bcm.edu/oivm

Core provides instrumentation, imaging and image analysis tools.Ddicated to vital and intravital imaging of cellular processes within cells, intact tissue explants, developing embryos and functioning organs within the live animal. Our users are focused on a variety of applications such as understanding cell migration, optimizing angiogenic therapies, how blood flow influences development and cancer, immune cell recruitment, stem cell-niche interactions and cancer metastasis.

Proper citation: Baylor College of Medicine Optical Imaging and Vital Microscopy Core Facility (RRID:SCR_019297) Copy   

•   Source: SciCrunch Registry

https://ki.mit.edu/sbc/histology

Core assists in producing quality histological slides.Provides equipment and expertise to produce sections from frozen, paraffin-embedded, and resin-embedded tissues,routine hematoxylin and eosin stained slides, immunohistochemical and special stains.Registration to iLab required.

Proper citation: Massachusetts Institute of Technology Koch Institute Histology Core Facility (RRID:SCR_019177) Copy   

•   Source: SciCrunch Registry

https://www.uclalipidomics.net/

Offers automated sample preparation and two distinct mass spectrometry platforms with services, ranging from shotgun lipidomics to isotope labeling and mathematical modeling of lipid flux parameters.Offers data analysis and consultation services to provide users with accurate analysis of lipid metabolic parameters.

Proper citation: University of California at Los Angeles Lipidomics Lab Core Facility (RRID:SCR_019210) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/facility/biokem/

Provides single particle cryo EM and cryo tomography of plunge frozen samples. Using Titan Krios G3i for high resolution data collection on Gatan K3 Direct Detection Camera facility is able to offer data collection at atomic level resolution.Facility uses Serial EM for SPA and cryo-ET data acquisition.

Proper citation: Colorado University at Boulder BioChemistry Krios Electron Microscopy Core Facility (RRID:SCR_019057) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/rc/resources/petalibrary

Provides service to support storage, archival, and sharing of research data. Available at subsidized cost to any researcher affiliated with University of Colorado Boulder.

Proper citation: University of Colorado Boulder High Performance Computing PetaLibrary Core Facility (RRID:SCR_019299) Copy   

•   Source: SciCrunch Registry

https://medicine.uky.edu/centers/cobre/protein-core

Core provides nanobodies production for research as well as protein production, purification, and macromolecular characterization. Offers training on all instruments and equipment, as well as higher level of assistance when projects warrant.

Proper citation: University of Kentucky College of Medicine Protein Core Facility (RRID:SCR_019172) Copy   

•   Source: SciCrunch Registry

https://www.as.miami.edu/faculty-and-staff/center-for-advanced-microscopy--umcam/

Provides scanning electron microscopy services including biological tissues and cells,and particulate characterization.

Proper citation: University of Miami Center for Advanced Microscopy Core Facility (RRID:SCR_019173) Copy   

•   Source: SciCrunch Registry

https://www.forsyth.org/research/services/

Core offers micro 3D X-ray imaging of small samples in high resolution and provides images and quantitative analyses of internal structures of ex vivo samples without any destructive procedures.Scanco CT40 system allows for visualization, measurement, and quantification of the structure of mineralized specimens. Contrast reagents permit visualization of soft tissue structures such as blood vessels.System creates 3D model from stack of 2D X-ray images taken around single axis of rotation. High-resolution scanner can capture detail at resolution of 6 to 32 microns. Non- destructive nature of this technology allows investigators to carry out complementary analyses of the same sample. There are two dedicated workstations for analyzing microCT data, the SCANCO analysis software or the Amira software package with XImagePAQ extension.

Proper citation: Forsyth Institute Micro Computed Tomography Core Facility (RRID:SCR_021180) Copy   

•   Source: SciCrunch Registry

https://www.lsi.umich.edu/science/centers-technologies/cryo-electron-microscopy

Facility uses MiCores/iLab to schedule time on microscopes.Allows scientists to study form and function of biological machines that are too large to study using X-ray crystallography. Provides instruments and faculty expertise specializing in cryo electron microscopy.

Proper citation: University of Michigan Ann Arbor Life Sciences Institute Cryo Electron Microscopy Core Facility (RRID:SCR_021343) Copy   

•   Source: SciCrunch Registry

https://mass-spec.ku.edu/

Provides range of mass spectrometry based services including small molecule analysis and quantitation, peptide and protein MW determination; MS based proteomics services and associated bioinformatics including: global proteome IDs and targeted proteomics, post-translational modification mapping, quantitative proteomics, consultation for designing proteomics experiments, thermal protein profiling and cellular thermal shift assay analysis.

Proper citation: University of Kansas Mass Spectrometry and Analytical Proteomics Core Facility (RRID:SCR_021857) Copy   

•   Source: SciCrunch Registry

https://med.uottawa.ca/core-facilities/facilities/histology

Core is full service histology laboratory available to faculty, researchers, clinicians and students.Provides histological services for both animal and human tissue. Services include paraffin processing and embedding, paraffin and frozen sectioning as well as routine and special histological staining.Equippemnt includes:Leica Bond III Immunostainer to provide automated immunohistochemistry, in-situ hybridization and immunofluorescence staining;Automated tissue processors for paraffin processing; Automated microtomes for paraffin sectioning; Automated stainer that can be programmed to provide wide variety of routine and special stains;Cryostats for sectioning frozen tissue; Tissue Microarray machine.LPHCF can also perform manual chromogenic or fluorescent staining (single or multi-color labelling) on frozen and paraffin sections. We also provide full service slide scanning using Axio Scan.Z1 for Brightfield or Fluorescent stained slides at either 20X or 40X magnification.Personnel in the LPHCF are available for consultation on project/protocol design, technical assistance and training on facility instruments.Infinity software system is used for all of our histological services and instrument training.

Proper citation: University of Ottawa Louise Pelletier Histology Core Facility (RRID:SCR_021737) Copy   

•   Source: SciCrunch Registry

http://cbic.yale.edu

Core has range of instruments for characterization and structure elucidation of chemical and biophysical samples. Our staff maintains instruments and provides data collection services as well as training and support for self use of many of our instruments. We are most equipped in areas of NMR spectroscopy, Mass spectrometry and X-ray crystallography, but we also have optical and calorimetric instruments.

Proper citation: Yale University Chemical and Biophysical Instrumentation Center Core Facility (RRID:SCR_021738) Copy   

•   Source: SciCrunch Registry

https://ibsc.ucsc.edu/facilities/cell-culture-facility

Provides services for culture and analysis of stem cells. Provides space for embryonic stem cell growth and manipulation. Facility staff offers expertise in experimental design, protocol development, and data analysis.Equipment including biosafety hoods, centrifuges, microscopes.

Proper citation: University of California at Santa Cruz Institute for Biology of Stem Cells Cell Culture Core Facility (RRID:SCR_021353) Copy   

•   Source: SciCrunch Registry

https://www.atcc.org/services

Core genomics and bioinformatics group at American Type Culture Collection.Offers whole genome sequencing and advanced bioinformatics analysis for wide range of biological materials ranging from viruses and bacteria, to fungi and human or animal cell lines, genome assembly, verified annotation, functional genomics analysis, transcriptomics analysis, cell line contamination assessments, microbiome profiling, and advanced cell line authentication services.

Proper citation: American Type Culture Collection Sequencing and Bioinformatics Center Core Facility (RRID:SCR_021346) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/sweet/provider?uri=http://hawaii.eagle-i.net/i/0000012a-2510-c9ec-c99c-aef680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 19,2022. Provides services for flow cytometry, cell sorting and immunological services through COBRE support. Helps in developing new or customized immunological methods for COBRE Investigators and other Core users, regularly schedules training sessions are held for COBRE Investigators and other faculty and students across university and broader research community.Services include Flow Cytometry, Analysis and Sorting,Cell Counting, Size, and Viability,Multiplex Bead Assays including Luminex and CBA Platforms for DNA, Protein, and Antibodies Assays, Immunospot Plate Reading including ELISpot and FRNT, Cell Irradiation. Flow Cytometry Assays including Cell Phenotyping, Cell Cycle with Live or Fixed Cells, Apoptosis, FRET, Calcium Flux, Phosphorylation, Intracellular Cytokine and Protein Detection, Fluorescent Protein Expression,Cell Population Isolation, Single Cell Sorting, Dye Dilution Assays, Proliferation,Training opportunities.Experienced staff will provide hands-on training to investigators in conducting IBC/IACUC/CHS approved MCI research protocols. Please refer to MCI training document to help you get started on the process for obtaining clearance to work in the JABSOM Molecular and Cellular Immunology Core Facility.

Proper citation: University of Hawaii at Manoa Molecular and Cellular Immunology Core Facility (RRID:SCR_021344) Copy   

•   Source: SciCrunch Registry

https://www.biotech.cornell.edu/core-facilities-brc/facilities/flow-cytometry-facility

Facility provides training, consulting, assisted use and independent access for wide variety of cell sorting and analysis.

Proper citation: Cornell University BRC Flow Cytometry Core Facility (RRID:SCR_021740) Copy   

•   Source: SciCrunch Registry

https://research.ouhsc.edu/Core-Facilities/Laboratory

Core facility offering services involving DNA, protein, and whole cell analysis. Services include sequencing (custom PCR, plasmid and DNA, RNA, 16s, miRNA, ChIP ) and microsatellite detection via Illumina MiSeq or SeqStudio capillary sequencer. Expression analysis using Nanostring nCounter SPRINT platform, Mass Spectrometry and Proteomics using Waters Synapt with 2D UPLC. Provides qualitative and quantitative analysis of protein samples (cell lysate, IP, in solution) as well as simple protein identification from solution or gel slice. Flow and Imaging division offers BSL2 cell sorting, flow cytometry, Luminex, and confocal imaging.

Proper citation: University of Oklahoma Health Sciences Center Laboratory for Molecular Biology and Cytometry Research Core Facility (RRID:SCR_021345) Copy   

•   Source: SciCrunch Registry

https://www.biotech.cornell.edu/core-facilities-brc/facilities/imaging-facility

Facility provides instrumentation and training in following areas of High resolution X-ray CT,Small animal X-ray CT,Flow cytometry and sorting,Confocal microscopy,Multiphoton microscopy,Super resolution microscopy,Laser capture microdissection,Light microscopy,Spectrofluorometry,Bioluminescence imaging,High resolution ultrasound imaging,Image visualization and analysis.

Proper citation: Cornell University BRC Imaging Core Facility (RRID:SCR_021741) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/immunology-and-microbiology

Provides access to high parameter cell analysis and sorting instrumentation along with scientific expertise.Services provided include Cell Sorting,FACS Cell Sorting,Flow Cytometric Analysis,Multi-color Flow Cytometry,Spectral Flow Cytometry.

Proper citation: University of Colorado Anschutz Medical Campus ImmunoMicro Flow Cytometry Core Facility (RRID:SCR_021321) Copy   

•   Source: SciCrunch Registry

https://medicine.uky.edu/centers/cobre/genetic-technologies-core

Core provides services related to manipulation and delivery of nucleic acids to biological systems. Services include Production and titering of recombinant viral vectors,including Lentiviruses, Adenoviruses, and Adeno associated viruses;Subcloning;Tagging of open reading frames;Development of plasmids and/or RNAs for CRISPR/Cas manipulation;piggyBac transposon delivery systems;Real-time PCR analysis;Recombineering;In vitro transcription; Core maintains stock of plasmids that provide components for building constructs envisioned by investigator and provides consultative services.Provides training opportunities in the technologies described above, either as a for-credit, one semester class or on a project-related, fee-based basis.

Proper citation: University of Kentucky College of Medicine Genetic Technologies Core Facility (RRID:SCR_021285) Copy   

•   Source: SciCrunch Registry