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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://labnodes.vanderbilt.edu/vger
Provides services, consultation, and collaborations to enable generation, storage and regeneration of genetically altered mice.Services include CRISPR-Cas9 Mouse Editing, Pronuclear Microinjection of DNAs,Sperm or Embryo Cryopreservation,In vitro Fertilization and Rederivation,Genome-Editing Design and Analysis Services.
Proper citation: Vanderbilt University Genome Editing Resource Core Facility (RRID:SCR_018826) Copy
https://research.uky.edu/abebc
Core primary focus is to identify mechanisms linking obesity to cardiovascular disease. Provides equipment and technical expertise for measurement of lean/fat mass and whole body metabolism in mice. Provides equipment for computerized quantitative measurement of oxygen consumption, food intake, water intake, and physical activity in mice.Echo MRI is utilized for non invasive quantitative assessment of lean and fat mass.
Proper citation: Kentucky University, Lexington, Energy Balance and Body Composition Core Facility (RRID:SCR_018825) Copy
https://www.biotech.iastate.edu/Hybridoma/
Core provides services for monoclonal or polyclonal antibodies production,animal immunization, cell fusion and hybridoma culture maintenance, cell culture and maintenance of other cell lines used in biotechnology and virology labs, large scale mammalian cell culture (bioreactor), blood sera collection, antibody purification and isotyping, cryopreservation and cryostorage of cell lines, and ELISA tests.
Proper citation: Iowa State University Hybridoma Core Facility (RRID:SCR_018829) Copy
https://isb3d.pharmacy.vcu.edu/resources/
Core provides services for Molecular Modeling, Biophysical Techniques, X-ray Crystallography, Protein Production,High Throughput Screening. Provided instruments to use after reservation include Clariostar Multimode Plate Reader, Echo 550 Acoustic Liquid Handler, X-Ray Diffractometer.
Proper citation: Virginia Commonwealth University School of Pharmacy Institute for Structural Biology, Drug Discovery and Development Core Facility (RRID:SCR_018832) Copy
Provides development and support of genomics-based research, serving investigators in Nevada and beyond. Staff can be contracted for select services including ABI 3130 DNA sequencing, BD FACSCalibur flow cytometry, Affymetrix microarray processing, Agilent 2100 Bioanalyzer analysis and Qubit analysis. Facility also provides equipment and training for real-time PCR, Western blot/gel/microarray scanning, and analysis of DNA, RNA and protein samples.
Proper citation: Nevada University Genomics Core Facility (RRID:SCR_018272) Copy
Contract Research Org. specializing in custom protein analysis. Services Provided include SDS PAGE analysis, Western Blotting, Mass Spectrometry, protein staining ( silver,coomassie) for academia, federal institutions and industry.
Proper citation: Kendrick Labs Core Facility (RRID:SCR_018271) Copy
Core provides scientific consultation, training and access to shared biophysical equipment for characterization and analysis of macromolecules and their complexes. Facility includes instruments measuring molecular interactions and assessing protein quality by Isothermal Titration Calorimetry (ITC), Surface Plasmon Resonance (SPR), Biolayer Interferometry (BLI), MicroScale Thermophoresis (MST), Differential Scanning Fluorimetry (DSF), Circular Dichroism (CD), Analytical Size Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS), and Dynamic Light Scattering (DLS).
Proper citation: Harvard Medical School Center for Macromolecular Interactions Core Facility (RRID:SCR_018270) Copy
Offers instrumentation and technical capabilities and plays significant consultative role in application of these technologies to basic science projects.Genomic Services include Oligo Synthesis,Gene Expression,Real-Time PCR,PyroSequencing,Next-Generation Sequencing (NGS),DNA Sequencing (Sanger)/Fragment AnalysisSingle Cell Genomics,RNA-DNA QC - Bioanalyzer and Fragment Analyzer QC.Protein Services include Peptide Synthesis,Mass Spectrometry,Protein Analytics - Mass Mapping/Edman Sequencing,Surface Plasmon Resonance (Biacore).
Proper citation: Stanford University School of Medicine Protein and Nucleic Acid Core Facility (RRID:SCR_018668) Copy
Core provides imaging equipment including JEOL 1400 transmission electron microscope with AMT 11 megapixel digital camera,JEOL JSM 6060 scanning electron microscope with attached Oxford INCA energy dispersive spectroscopy detector for element analysis,Nikon Air HD confocal scanning laser microscope, Nikon C2 confocal scanning laser microscope, Andor Spinning Disk confocal microscope, Zeiss LSM 7 Multiphoton confocal microscope, Nikon STORM super-resolution light microscope, Olympus BX50 research microscope for transmitted light, phase contrast, and epi-fluorescence microscopy, Asylum Research MFP-3D BIO atomic force microscope, Asylum Research Cypher Environmental atomic force microscope,Arcturus XT-Ti Laser Capture Microdissector system, Olympus IX70 inverted microscope with associated Applied BioPhysics Electri Cell-Substrate Impedance Sensing (ECIS Ztheta) system, Leica VERSA 8 whole slide imager, Dell workstations containing Molecular Devices MetaMorph image analysis software for complex quantitative image analysis, Indica Labs HALO software, Improvision Volocity, MBR StereoInvestigator.
Proper citation: Vermont University Larner College of Medicine Microscopy Imaging Center Core Facility (RRID:SCR_018821) Copy
https://www.albany.edu/genomics/microarray-ngs.html
Provides services for DNA microarrays for large scale analysis of gene expression,gene regulation, exon splicing, epigenetics. Provides instrumentation for scanning of protein arrays.Offers services in RNA sequencing, ChIP-seq, ChIRP-seq, metagenomics and miRNA sequencing.Provides bioinformatics tools for analysis of results of microarray and sequencing experiments. Houses Illumina Nextseq500 and Ion PGM platforms for next generation sequencing. Provides instruments for Next gen sequencing including Illumina, MinIon, Wafergen-Takara, 10x genomics and for DNA microarrays including Affymetrix, Agilent.
Proper citation: University at Albany SUNY Center for Functional Genomics Microarray and Next Gen Sequencing Core Facility (RRID:SCR_018262) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/precision-immunology-laboratory
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 20,2025. Core to study immune cell phenotype and function, characterizes antitumor immune responses, determines mechanisms of immune escape and evasion, and develops biomarkers that predict patient outcomes or possible toxicities. Offers services for immune monitoring,provides expert knowledge that guides choice of technologies used for study, coordinates purchase, quality control, and use of reagents. Stand-alone services include high-quality cell processing and storage to support correlative studies. These services allow convenient batched analysis of trial samples.Staff purifies peripheral blood mononuclear cells daily from clinic visits and another staff member is available for on-demand and after-hours processing. Samples are cryopreserved on-site in temperature-monitored LN2 freezers for short-term storage. For long-term storage, samples are transferred to Novare Biologistics,off-site cGMP-compliant, New York State-licensed, and FDA-registered biorepository. Routinely assess quality of processing and cryopreservation. Core meets performance targets for cell viability and recovery necessary for certification by Integrated Biobank of Luxembourg. Offers service for isolating tumor-infiltrating lymphocytes using dissociation protocols optimized for various tumor tissues. Offers flow cytometry at Perlmutter Cancer Center, along with expert service and training. Sterile fluorescence-activated cell sorting (17 colors) is routinely performed with options for high-speed (50K cells per second), single-cell deposition (into polymerase chain reaction plates), and BSL-3 sorting for unscreened or infected human material. Data analysis workstations are also available.Offers single-cell analysis through our cutting-edge 30-parameter flow cytometry technology and Integrated Molecular Cytometry Platforms (IMCPs).
Proper citation: New York University School of Medicine Langone Health Precision Immunology Laboratory Core Facility (RRID:SCR_017936) Copy
Core provides services including high throughput next generation sequencing (NGS) to support whole genome, whole exome, RNA-Seq, single cell RNA-Seq, microbiome and global chromatin and methylation studies, biostatistical and bioinformatic support for NGS projects, access to DNA/RNA sequence analysis software, automated Sanger DNA sequencing, genotyping and RNA/DNA quality assessment, access to shared instrumentation such as plate readers, real time thermal cyclers, Agilent Bioanalyzers, fluorimeters, and spectrophotometers.
Proper citation: Marshall University School of Medicine Genomics Core Facility (RRID:SCR_018885) Copy
https://med.virginia.edu/gatc/
Core offers instrumentation and expertise in all areas of bulk and single cell NGS genomics and transcriptomics, as well as training to access core shared instrumentations. Services include RNA Seq, CHIP Seq, ATAC Seq, Amplicon DNA Seq, 16S ribosomal gene sequencing, shot gun sequencing for small genomes and whole exome sequencing.10X Genomics resources include single cell CNV, VDJ, and 3 or 5 RNA seq as well as linked reads.Core provides real time and droplet digital PCR services most suitable for targeted gene expression, SNP genotyping and CNV discovery.
Proper citation: Virginia University School of Medicine Genome Analysis and Technology Core Facility (RRID:SCR_018883) Copy
https://www.colorado.edu/lab/cufemm/
Facility features electron microscopes housed in vibration, static-free, and temperature-controlled environment.
Proper citation: Colorado University at Boulder Facility for Electron Microscopy of Materials Core Facility (RRID:SCR_019306) Copy
https://www.colorado.edu/facility/mimic/
Facility provides specialized services for assessment of material properties, chemistry and structure across multiple length scales with emphasis on assessment of biological tissues, biomaterials, and biologically inspired systems.
Proper citation: Colorado University at Boulder Materials Instrumentation and Multimodal Imaging Core Facility (RRID:SCR_019307) Copy
https://www.colorado.edu/sharedinstrumentation/core-facilities/biofrontiers-sequencing-core
Core instruments include Agilent Bioanalyzer 2100 system provides sizing, quantitation and quality control of DNA, RNA and proteins, Illumina MiSeq sequencer, able to sequence prepared Illumina DNA or RNA libraries at low- to mid- output (0.75 to 13 Gbp per run), Illumina NextSeq sequencer capable of sequencing Illumina DNA or RNA libraries, QuantStudio 6 Real-Time PCR uses fluorescence detection method for quantitative and qualitative analysis of nucleic acid sequences including gene expression, regulation and variation, Qubit Fluorimeter 3.0 capable of measuring DNA or RNA concentrations with high accuracy.
Proper citation: Colorado University at Boulder BioFrontiers Next-Gen Sequencing Facility Core Facility (RRID:SCR_019308) Copy
http://www.biotech.ufl.edu/cores/monoclonal-antibody/
Core develops new mouse monoclonal antibodies for investigators to use in basic and applied research.Provided services include immunization of mice, cell fusion, cell cloning, screening by ELISA and Western blot, monoclonal antibody production, purification and labeling, monoclonal antibody analyses such as antibody/antigen affinity measurements, epitope binning and identification of matched antibody pairs. Customer training on select self-service instruments is also offered.
Proper citation: University of Florida ICBR Monoclonal Antibody Core Facility (RRID:SCR_019147) Copy
http://smrc.colorado.edu/facilities/xrd_saxs.html
Provides cutting edge capabilities for probing large lengthscale structures such as polymers, biological macromolecules, meso- and nano-porous materials, and molecular self-assemblies.Techniques that can be applied to study materials include SAXS, GISAXS, WAXS, and GIWAXS. The 30W Xenocs Genix 3D x-ray source and state-of-the-art Dectris Eiger R 1M detector provide an excellent way to probe almost any material of interest. In-situ x-ray studies may be carried out using temperature controlled sample holders in both SAXS and GISAXS modes..
Proper citation: Colorado University at Boulder Soft Materials Research Center X-Ray Diffraction Facility Core Facility (RRID:SCR_019304) Copy
http://www.biotech.ufl.edu/cores/electron-microscopy/
ICBR Electron Microscopy supports researchers in visualizing microscopic structures through imaging projects and user training. Provided serives include room temperature and cryo transmission and scanning electron microscopy, confocal laser scanning microscopy, sample preparation and user training.
Proper citation: University of Florida ICBR Electron Microscopy Core Facility (RRID:SCR_019146) Copy
https://case.edu/medicine/genomics/
Core provides centralized resource working to take difficulty out of Next Generation Sequencing projects for both novice and experienced users alike. Provides assistance in all facets of experimentation from design to data analysis including grant and manuscript preparations.Offers NGS, Sanger, Informatics and Genotyping services based off of Illumina platform.
Proper citation: Case Western Reserve University Genomics Core Facility (RRID:SCR_019021) Copy
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