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https://chemh.stanford.edu/research/knowledge-centers

Shared resource to provide instrumentation and scientific expertise to Stanford researchers.Each Knowledge Center is organized around specific scientific area and offers services to the research community. Services, advice, training and instrument access, include area in High-Throughput Screening, Medicinal Chemistry, Crystallography, Cryo-EM, Metabolomics, Protein engineering, Protein expression.

Proper citation: Stanford Sarafan Chemistry, Engineering and Medicine for Human Health Knowledge Centers Core Facility (RRID:SCR_023238) Copy   

•   Source: SciCrunch Registry

http://www.nextgen.pitt.edu

Sequencing Core offers Illumina next generation sequencing services to University of Pittsburgh research community. Offers expertise in next generation sequencing technologies. Encourages to contact Assistant Director to arrange for consultation.Staff is available to share their experience and expertise to assist with development of projects of all sizes, standard or custom assay design, and other specialized application needs.

Proper citation: University of Pittsburgh Medical Center Children Hospital of Pittsburgh Health Sciences Sequencing Core Facility (RRID:SCR_023116) Copy   

•   Source: SciCrunch Registry

https://chemh.stanford.edu/research/knowledge-centers/protein-engineering

MSKC is main gateway for Stanford faculty and students interested to study biological molecules using SLAC X-ray facilities and other major bioimaging facilities.

Proper citation: Stanford Sarafan Protein Engineering Knowledge Center Core Facility (RRID:SCR_023237) Copy   

•   Source: SciCrunch Registry

https://chemh.stanford.edu/research/knowledge-centers/metabolomics

Provides scientific expertise and instrumentation for measurement of small molecules such as metabolites and lipids to ChEM-H and Stanford communities. Leverages expertise in mass spectrometry and allied techniques to understand biology of small molecules both metabolites and xenobiotics and to apply that understanding to advances in human health.

Proper citation: Stanford Sarafan Metabolomics Knowledge Center Core Facility (RRID:SCR_023236) Copy   

•   Source: SciCrunch Registry

http://www.arpege.cnrs.frCore FacilityArpege

Offers functional and structural analysis of protein complexes.Offers possibility to characterize all types of molecular interactions: ligand-target binding, protein-protein interactions, signal transduction, and signalling complexes. Staff members are skilled specialists in luminescence-based techniques and in receptor biology.Application portfolio includes Analysis of cell signalling, by measuring signal transduction;Ligand-target binding (pharmacological analysis, affinity, selectivity); Protein-protein interactions (oligomerization, effectors...); Activation of signalling pathways (G proteins, GRK, arrestins & internalization); Intracellular production of second messengers (cAMP, IP1, Ca2+); Phosphorylation of signalling proteins (ERK, AKT...); Measurement of global cell functions and of different cell parameters (proliferation, migration, invasion...).

Proper citation: Arpege Core Facility (RRID:SCR_023092) Copy   

•   Source: SciCrunch Registry

http://www.mgx.cnrs.fr

Offers genomic technologies to academic laboratories and biotechnology companies.Application portfolio includes Whole genome (re)sequencing, including the identification of variants (SNVs, mutations, indels, CNVs);Targeted sequencing, for instance exomes; Transcriptome analyses (RNA-Seq, small RNA-Seq, microarrays), including in single cells (single-cell 3 RNA-seq); Determination of chromatin structure and dynamics (ChIP-Seq, FAIRE-Seq, Hi-C); Epigenetic analyses (ChIP-Seq, RRBS, Bisulphite-Seq);Genotyping (RAD-Seq, GBS, microarrays).

Proper citation: Montpellier GenomiX Core Facility (RRID:SCR_023091) Copy   

•   Source: SciCrunch Registry

https://neuroscience.stanford.edu/research/neuroscience-community-labs/neuroscience-microscopy-service

Provides microscopy expertise and access to high resolution, state-of-the-art imaging technologies to Stanford University and surrounding academic and biotech researchers. Core provides training, design, implementation, and analysis assistance.

Proper citation: Stanford Neuroscience Microscopy Service Core Facility (RRID:SCR_023257) Copy   

•   Source: SciCrunch Registry

https://neuroscience.stanford.edu/research/neuroscience-community-labs/neurosciences-preclinical-imaging-laboratory

Provides preclinical Magnetic Resonance Imaging technology and expertise to Stanford community. Offers range of support from full project to independent user operation and training.

Proper citation: Stanford Neuroscience Preclinical Imaging Laboratory Core Facility (RRID:SCR_023254) Copy   

•   Source: SciCrunch Registry

https://geochronology.stanford.edu/

Core for comprehensive examination of evolution of Earth's crust using geochronologic approaches. Provides spectrum of analytical facilities that are all housed within School of Earth, Energy and Environmental Sciences.Provides data to many disciplines throughout geosciences, including tectonics, geodynamics, petrology, geochemistry, geomorphology, sedimentology, stratigraphy, paleontology, and paleoclimatology.

Proper citation: Stanford Geochronology Cluster Core Facility (RRID:SCR_023252) Copy   

•   Source: SciCrunch Registry

https://www.rockefeller.edu/crispr/

Provides gene targeting and mouse embryonic stem cell technology for members of Rockefeller University, Memorial Sloan-Kettering Cancer Center and their collaborators.CRISPR and Genome Editing services include mouse genomic knock-out and knock-in, mouse conditional knock-out, establishing new ES lines for gene targeting services, establishing ES lines from mutant mouse embryos, preparing ES cells introduced from off campus resources for injection or other application, assisting in embryoid body culture and in vitro differentiation of ES cells, and purification and evaluation of DNA for pronuclear injection.

Proper citation: Rockefeller University CRISPR and Genome Editing Resource Center Core Facility (RRID:SCR_023097) Copy   

•   Source: SciCrunch Registry

https://pnf.uchicago.edu

Facility is ISO Class 5 cleanroom that specializes in advanced lithographic processing of hard and soft materials. Facility is focused on supporting basic science, applied research, research and development, and prototype production using micro and nanofabrication.

Proper citation: University of Chicago Pritzker Nanofabrication Core Facility (RRID:SCR_022955) Copy   

•   Source: SciCrunch Registry

https://research.med.psu.edu/core-facilities/hpc/

Provides computational and storage tools needed to efficiently and effectively process data. High performance computing cluster housing compute cores, graphical processing unit cores, and directly attached high speed storage.

Proper citation: Penn State College of Medicine High Performance Computing Core Facility (RRID:SCR_022953) Copy   

•   Source: SciCrunch Registry

https://neuroscience.stanford.edu/research/neuroscience-community-labs/behavioral-and-functional-neuroscience-laboratory

Laboratory at Wu Tsai Neursciences Institute provides preclinical discovery platform for central nervous system target validation in preclinical in vivo and in vitro models. Neurobehavioral assessment tools in CNS disease models provide platform for screening and profiling of experimental therapeutics and genetic rodent models. Used to support understanding of human CNS disorders and development of therapeutic interventions.

Proper citation: Stanford Behavioral and Functional Neuroscience Laboratory Core Facility (RRID:SCR_023249) Copy   

•   Source: SciCrunch Registry

https://research.utexas.edu/cbrs/cores/cem/

Offers training, assisted and unassisted use of microscopes and equipment, as well as consultations and collaborations. Support includes single particle cryo-EM, Cryo-ET, Micro-ED,simple characterization of samples in vitrified aqueous mixtures (e.g. nanoparticle size, etc.).

Proper citation: University of Texas at Austin Cryo Electron Microscopy Core Facility (RRID:SCR_022951) Copy   

•   Source: SciCrunch Registry

https://npc.cnsi.ucla.edu/

Offers curated collection of high end scientific instrumentation to enable physicochemical characterization of nanoscale materials, devices, and systems under wide range of experimental conditions.Technical capabilities and expertise include surface analysis by Scanning Probe Microscopy (SPM); hydrodynamic size and surface charge analysis by Dynamic Light Scattering (DLS) and Zeta Potential (ZP) measurements; elemental and chemical analysis by Inductively Coupled Plasma Mass Spectrometry (ICP-MS).

Proper citation: University of California at Los Angeles California NanoSystems Institute Nano and Pico Characterization Laboratory Core Facility (RRID:SCR_022924) Copy   

•   Source: SciCrunch Registry

https://www.ou.edu/microscopy

Offers access to instrumentation, training, and service using advanced light microscopy, scanning electron microscopy, and transmission electron microscopy. Provides access to core imaging and analytical characterization technologies. In addition to instrument access, SRNML personnel offer advice, hands-on training, education, and research collaboration. Provides range of sample preparation equipment.

Proper citation: University of Oklahoma Samuel Roberts Nobel Microscopy Laboratory Core Facility (RRID:SCR_022929) Copy   

•   Source: SciCrunch Registry

https://voices.uchicago.edu/proteomics/

Core to develop and utilize proteomics techniques to answer both basic and translational scientific questions.

Proper citation: University of Chicago Proteomics Platform Core Facility (RRID:SCR_022928) Copy   

•   Source: SciCrunch Registry

https://www.mcw.edu/departments/genomic-sciences-and-precision-medicine-center-gspmc

Core for advancing genomic sciences and precision medicine in fields of Omics, Data Science, and Systems Biology. Provides whole genome sequencing technologies to investigate how gene variants impact gene expression and to define genetic variants associated with rare and common disease, embryonic development, and effects of environmental factors and drugs upon gene expression and disease.

Proper citation: Medical College of Wisconsin Mellowes Center for Genomic Sciences and Precision Medicine Core Facility (RRID:SCR_022926) Copy   

•   Source: SciCrunch Registry

https://inml.cnsi.ucla.edu/

Nanomaterials and nanostructures grown in INML are used in lasers, solar cells, detectors, transistors, modulators, and a wide range of other electronic and photonic devices.

Proper citation: University of California at Los Angeles California NanoSystems Institute Integrated NanoMaterials Laboratory Core Facility (RRID:SCR_022925) Copy   

•   Source: SciCrunch Registry

https://snf.stanford.edu/

One of four labs that are part of nano@stanford, under NSF National Nanotechnology Coordinated Infrastructure program. SNF includes cleanroom housing tools for device fabrication, satellite labs supporting Metal Organic Chemical Vapor Deposition,Experimental Fabrication methods and electronics shop for Systems Prototyping. SNF supports researchers in applications ranging from medicine and biology to fundamental physics and astronomy.

Proper citation: Stanford Nanofabrication Core Facility (RRID:SCR_023234) Copy   

•   Source: SciCrunch Registry