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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://researchservices.pitt.edu/facilities/glass-shop
Core is responsible for fabricating and repairing intricate pieces of glassware and apparatus, as well as constructing complete high vacuum systems.
Proper citation: University of Pittsburgh Dietrich School Glass Shop Core Facility (RRID:SCR_023719) Copy
https://uclouvain.be/en/research-institutes/irec/cytoflux
Offers tissues dissociation and single cell preparation, analysis and cell sorting under supervision of research logistician.Provides instruments BD FACSCantoII for analysis and BD FACSAriaIII for cell separation and services including Samples preparations and multiparametric panels consultancy, Acquisition and analysis of multiparametric samples, Cell Sorting, Data Analysis.
Proper citation: Catholic University of Louvain Institute of Experimental and Clinical Research Flow Cytomerty Platform Core Facility (RRID:SCR_023664) Copy
Imaging facility of Life Sciences Institute with state-of-the-art fluorescence microscopy equipment. Applications include FLIM, FRET, FRAP, TIRF and high throughput content screening (small molecule and siRNA). Provides access, user training, and technical assistance for super resolution microscopy, confocal microscopy (point laser scanning or spinning disk), high throughput imaging and image deconvolution, 3D reconstruction, and quantitative analysis.
Proper citation: University of British Columbia LSI Imaging Core Facility (RRID:SCR_023783) Copy
https://www.bcchr.ca/gut4health
Facilitates microbiome studies for researchers at British Columbia Children Hospital Research Institute and University of British Columbia. Core offers processing and storing biological specimens, and sequencing and analysis of microbial communities for various research studies, including basic science, clinical, translational, and epidemiological projects.
Proper citation: University of British Columbia Gut4Health Microbiome Core Facility (RRID:SCR_023673) Copy
https://rnainnovation.med.upenn.edu/scientific-groups/mrna-core/
Core focuses on exploring mRNA technology and lipid nanoparticles for various applications including tissue and cell targeting. Offers Optimization and production of in vitro transcribed mRNA, Small scale production of sequence optimized in vitro transcribed mRNA, Incorporation of modified nucleosides to modulate activity, Off the shelf in vitro transcribed mRNA encoding reporter genes or cancer antigens,Labelled mRNA for nanoparticle tracking and microscopy, Encapsulation into commercially available proprietary and non proprietary lipid nanoparticles through LNP core.
Proper citation: University of Pennsylvania Institute for RNA Innovation Engineered mRNA and Targeted Nanomedicine Core Facility (RRID:SCR_023665) Copy
https://www.sdstate.edu/biology-and-microbiology/functional-genomics-core-facility
Core provides access and training on range of instruments in areas of genomics, molecular biology, imaging, and chemical/metabolite analysis to support research on the SDSU campus.
Proper citation: South Dakota State University Functional Genomics Core Facility (RRID:SCR_023786) Copy
https://uclouvain.be/en/technology-platforms/pgen.html
Core provides services including Sequencing (Sanger, NGS); Genotyping (micro array, fragment analysis); Molecular karyotyping (micro array); Bioinformatics (exomes [WES], genomes [WGS], gene panels [panels], transcriptome [RNAseq]). Equipment includes Illumina MiSeq sequencer;Ion Torrent Ion Proton sequencer and an Ion Chef for sample preparation;HPC cluster for bioinformatics processing of NGS data (WES, WGS, panels, RNASeq);Affymetrix microarray platform;Sanger sequencer and fragment analyser;Contracts for outsourcing WES, WGS and RNAseq, according to public procurement regulations;Highlander software, developed in-house, for variant analysis from NGS data.
Proper citation: Catholic University of Louvain Genomics platform Core Facility (RRID:SCR_023707) Copy
https://sqi.northwestern.edu/core-facilities/antec/
Facility houses research equipment for evaluating materials and biological preparations, and offers 3D printing and 3D scientific illustration services. Available instruments include Cytation3 Automated Microscope Plate Reader, BioTek Inc.; Zetasizer Nano ZSP, Malvern Inc.; Lyophilizers FreeZone 6 and 6 Plus, Labconco; Azure300, Chemiluminescent Gel Imager, Azure Biosystems; Real-Time PCR I-cycler CFX-Connect, Bio-Rad Laboratories; Centrifuge Sorvall X1R, ThermoFisher; MCR302 Rheometer, Anton Paar Inc.; Plasma Cleaner, Harrick Plasma; NanoSight300, Malvern Instruments (Evanston); IncuCyte Live Cell Analysis System, Sartorius; Piuma Nanoindenter, Optics 11; Freezer/Mill, SPEX Sample Prep; J-1500 Circular Dichroism Spectrometer, JASCO.
Proper citation: Northwestern University Analytical BioNanoTechnology Equipment Core Facility (RRID:SCR_023706) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/proteomics-laboratory
Core offers specialized expertise for analysis of proteins and peptides using mass spectrometry. Develops new methods and customized approaches for proteomic analysis and suggests experimental strategies and sample preparation prior to mass spectrometry analysis. Services include:comprehensive protein identification ,analysis of affinity purified complexes,characterizing protein post-translational modifications,de novo sequencing,label and label-free quantitation ,multiplexed quantitation global phosphorylation and ubiquitin analysis,analysis of laser-capture microdissected formalin-fixed paraffin-embedded tissue,secretome analysis,crosslinking analysis,disulfide mapping.
Proper citation: New York University School of Medicine Langone Health Proteomics Laboratory Core Facility (RRID:SCR_017926) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/genome-technology-center
Core provides range of services related to genome, epigenome, and transcriptome analysis. Offers technologies including Illumina deep sequencing and sample preparation for variety of applications, including DNA and RNA sequencing (DNA- and RNA-seq), exome sequencing, targeted capture, chromatin immunoprecipitation sequencing (ChIP-seq), methylation sequencing (Methyl-seq), metagenomics, and many others;Automation of Illumina library and targeted capture preps, including 16S ribosomal RNA (rRNA) sequencing;Oxford Nanopore sequencing (long reads);Bio-Rad Droplet Digita polymerase chain reaction (PCR);Nanostring nCounter;Single-cell RNA- and DNA-seq using the C1 Auto Prep System from Fluidigm, and 10x Genomics Chromium System.Provides expertise on strategies to achieve research goals in any field related to genomics, and can tailor bioinformatics analysis to individual project. If you supply us with nucleic acids, we can perform every step required to help you achieve your desired results.
Proper citation: New York University School of Medicine Langone Health Genome Technology Center Core Facility (RRID:SCR_017929) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/genotyping-core-laboratory
Core provides fast, accurate, convenient, and affordable genotyping technologies. We use conventional polymerase chain reaction (PCR) and gel electrophoresis methods. By pooling samples from group of users, we can better ensure accuracy, cost-effectiveness, and quality control.
Proper citation: New York University School of Medicine Langone Health Genotyping Core Laboratory Core Facility (RRID:SCR_017932) Copy
Core mission is to drive scientific discovery through use of human specimens.Helps facilitate translational research, match human specimen resources to scientific needs, foster multi-investigator collaborative projects, and catalyze scientific innovation,improving researcher access to existing biospecimen resources, and enhancing institution-wide tissue-banking efforts and capacity. Another priority is to implement campus-wide policy for human biospecimen collection and storage to ensure regulatory compliance.
Proper citation: New York University School of Medicine Langone Health Center for Biospecimen Research and Development Core Facility (RRID:SCR_017930) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/animal-behavior/index.html
Provides investigators with expertise, equipment, and space that is required to conduct innovative acoustic, behavioral, and cognitive research with focus on rigor, reproducibility, and maintaining the highest standards of animal welfare.
Proper citation: University of Nebraska Medical Center Animal Behavior Core Facility (RRID:SCR_018830) Copy
Core provides researchers with flow cytometry and mass cytometry services and equipment and help from highly trained and experienced staff.
Proper citation: Maryland University School of Medicine Flow Cytometry and Mass Cytometry Core Facility (RRID:SCR_018835) Copy
https://www.labx.com/product/sciex-api-5000
Triple quadrupole liquid chromatography mass spectrometer for analysis of bioanalytical samples. It can be used for DMPK and ADME studies.API 5000 LC/MS/MS System delivers the lowest limits of detection for the most demanding DMPK and ADME studies.
Proper citation: SCIEX:: API 5000 Triple Quadrupole Liquid Chromatography Mass Spectrometer System (RRID:SCR_018437) Copy
Core facility is equipped with instrumentation to support proteomic and metabolomic research, as well as equipment for materials characterization. Key instruments include a Bruker 700MHz NMR, two Bruker XRDs (Powder and Crystal), and Bruker Micro ToF mass spectrometer.
Proper citation: Claflin University Molecular Science Research Center Core Facility (RRID:SCR_018836) Copy
http://tools.thermofisher.com/content/sfs/manuals/cms_041850.pdf
Automated peptide synthesizer for chain assembly steps in solid phase peptide synthesis or FastMoc chemistry. Data is based on conductance or ultraviolet UV absorbance of reagent, solutions, and solvents in the synthesis cycle.
Proper citation: Thermo Fisher: Applied Biosystems: 433A Peptide Sequencer (RRID:SCR_018440) Copy
https://fralinlifesci.vt.edu/core-services/mass-spectrometry-incubator.html
Facility supports Virginia Tech's research infrastructure as mass spectrometry analysis and education center. Provides training in sample preparation, instrument operation and data analysis, with strong emphasis on metadata and analytical requirements for publication of metabolomic and proteomic results.
Proper citation: Virginia Tech Mass Spectrometry Incubator Core Facility (RRID:SCR_017956) Copy
http://www.pasteur.fr/biophysics
Provides services and instrumentation for characterization of biological macromolecules with technical and methodological expertise. Provides characterization of macromolecules including shape, folding, stability auto-association,and they interactions including stoichiometry,thermodynamic and kinetic parameters.
Proper citation: Pasteur Institute Biophysics of Macromolecules and their Interactions Core Facility (RRID:SCR_018267) Copy
Established to produce immortalized cell lines from human blood (EBV transformations). Offers genomics applications for single cells, including RNA-seq, gene expression profiling by qPCR and DNA amplification for whole-genome or targeted (exome or PCR-based analysis) through 10x Genomics Chromium platform (similar to Drop Seq). Offers custom genotyping to analyze short tandem repeats, variable number tandem repeats and single nucleotide polymorphisms.
Proper citation: Johns Hopkins University School of Medicine Genetic Resources Core Facility (RRID:SCR_018669) Copy
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