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https://www.med.upenn.edu/chps/

CHPS is comprised of several Clinical Research Cores designed to facilitate research process. Provides resources, environment, operations, and training to support and promote high quality clinical and translational research by qualified investigators.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for Human Phenomic Science (CHPS) (RRID:SCR_022402) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/cear.html

Core aims to facilitate and build capacity for community based research and community engagement, while enhancing translation of research and technological developments to key public health and community stakeholders. Offers consultation on community engagement, training in participatory research methods, and assistance with development, implementation, and evaluation of community translation activities. Core is part of the Penn Institute for Translational Medicine and Therapeutics (ITMAT).

Proper citation: University of Pennsylvania Perelman School of Medicine Community Engagement and Research Core Facility (RRID:SCR_022408) Copy   

•   Source: SciCrunch Registry

https://genetics.med.upenn.edu/cores/tcmf/

Facility provides centralized service to efficiently produce genetically altered mice for basic research.� They include transgenic, chimeric and genome edited mice carrying transgenes or gene knockout and Knockin of specific interest.�Core also provides embryo and sperm cryopreservation as well as in vitro fertilization and re-derivation of live and cryopreserved lines, along with long-term storage of cryopreserved samples.

Proper citation: University of Pennsylvania Perelman School of Medicine Transgenic and Chimeric Mouse Core Facility (RRID:SCR_022388) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/neuronsrus/

Core supplies suspensions of neuronal cells prepared from rodent brain for various downstream applications, including primary cell culture. Supplies rat or mouse cells isolated from cortex or hippocampus either in suspension or plates. Custom dissection services are available for other brain regions or for user supplied genetically modified mice.

Proper citation: University of Pennsylvania Perelman School of Medicine Neurons R Us Core Facility (RRID:SCR_022421) Copy   

•   Source: SciCrunch Registry

https://www.themiamiproject.org/research-resources/core-facilities/drug-discovery-core/

Core at Miami Project to Cure Paralysis leverages PerkinElmer Opera Phenix Plus high content screening system to provide assay development and phenotypic screening. Facility is also equipped with PerkinElmer Janus G3 liquid handler, featuring modular and variable dispense heads, to automate screening workflows and enhance throughput. Core supports phenotypic and target-based assays. Phenotypic assays range from 2D to 3D, widefield to confocal, and antibody to dye based. It collaborates with users to develop customized assays and analytical pipelines tailored to their specific needs. Current specializations include neurite tracing, lipid droplet quantification, cell viability, morphological and kinetic analyses, phagocytosis, cell marker detection, cell adhesion, among others.

Proper citation: Drug Discovery Core Facility (RRID:SCR_022542) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/OCRCBioTrust/

Provides specimens including gynecologic cancer specimens such as fresh and frozen tissues, plasma, serum, peripheral blood mononuclear cells, blood, formalin fixed paraffin embedded (FFPE) samples, and Tissue Microarrays (TMAs). All samples collected have clinical annotation including demographic patient profiles, pathological and clinical notations, treatment history, and detail disease information, etc. We are building and maintaining centralized research database according to HIPPA specifications and Penn IRB standards.

Proper citation: University of Pennsylvania Perelman School of Medicine Ovarian Cancer Research Center Tumor BioTrust Collection Core Facility (RRID:SCR_022387) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/NBTC.html

Core provides equipment and services to investigate behavior phenotypes of models related to neurological and other disorders. Core is utilized by scientists across disciplines that are interested in behavioral consequences of unique physiological disruptions (e.g., metabolic, drugs etc.). Provides assessment of many domains of behavior including sensory, motor, social, communication, affect related behaviors and learning and memory. NTC was established in 2012 through generous startup funds from the Penn School of Medicine, the Institute for Translational Medicine and Therapeutics (ITMAT), Center for Sleep and Circadian Neurobiology (CSCN) and Penn Medicine Neuroscience Center (PMNC).

Proper citation: University of Pennsylvania Perelman School of Medicine Neurobehavior Testing Core Facility (RRID:SCR_022386) Copy   

•   Source: SciCrunch Registry

https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/core-facilities/saif-small-animal-imaging-facility

Core provides comprehensive suite of imaging modalities including magnetic resonance imaging (MRI), spectroscopy (MRS), optical imaging (including bioluminescence, fluorescence, and near-infrared imaging), computed tomography (CT), positron emission tomography (PET), single photon emission computed tomography (SPECT), and ultrasound (US). In addition, dedicated housing is available for mice and rats undergoing longitudinal imaging studies. Ancillary facilities and resources of SAIF are devoted to radiochemistry and image analysis.

Proper citation: University of Pennsylvania Perelman School of Medicine Small Animal Imaging Core Facility (RRID:SCR_022385) Copy   

•   Source: SciCrunch Registry

https://genetics.med.upenn.edu/cores/genomic-analysis-core/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 8th,2024. Facility offers sequencing services on three platforms, gold standard Sanger sequencing on ABI capillary sequencers, next generation sequencing (NGS) on Ion Torrent PGM and S5 and, Illumina MiSeq along with experimental design and data analysis.NGS service includes library preparation for multiple applications including targeted sequencing, RNA-Seq and Exome-Seq. Capillary sequencers also enable microsatellite genotyping and fragment analysis for VNTR, SNaPshot and Human Cell Line Authentication. Molecular biological services include PCR, cloning, subcloning, mutagenesis, construct preparation and, plasmid DNA preps at different scales.

Proper citation: University of Pennsylvania Perelman School of Medicine Penn Genomic Analysis DNA Sequencing Core Facility (RRID:SCR_022383) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/fmch/mixed-methods-research-lab

Fosters the use of qualitative and mixed methods research methodologies with focus on integrating key stakeholder perspectives and goals into research designs. Collaborates with investigators to address timely, pressing questions across diverse disciplines and works with investigators to provide conceptual as well as technical support for broad research programs, including clinical, community based, and implementation science research questions.

Proper citation: University of Pennsylvania Perelman School of Medicine Mixed Methods Research Lab Core Facility (RRID:SCR_022418) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/penn-microbial-culture-and-metabolomics-core

Provides equipment for aerobic and anaerobic culture of microbial species in both batch and continuous systems, as well as targeted metabolomic services of amino, bile, and short chain fatty acids. Offers training and usage for culture equipment; consultation regarding experimental design, and; anaerobic culture services. Examples of culture studies include isolation of microbial taxa from mammalian samples; interrogation of the physiology of microbial strains under different conditions (e.g., anaerobic/microaerobic/aerobic, differing nutrient limitations) using isolated strains or strains obtained from culture collections (another service offered by the core); co-culturing of defined microbial consortia to investigate microbe-microbe interactions, and; preparation of microbial products (live bacteria, heat-killed bacteria, bacterial supernatants) from single or defined-mixed microbial cultures for use in mammalian cell culture and/or animal model systems.

Proper citation: University of Pennsylvania Perelman School of Medicine Microbial Culture and Metabolomics Core Facility (RRID:SCR_022417) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/jf/bsbcore/index.html

Provides unique equipment and expertise to facilitate modern biophysical characterization and structural analysis of proteins and other biomolecules., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: University of Pennsylvania Perelman School of Medicine Johnson Foundation Biophysical and Structural Biology Core Facility (RRID:SCR_022414) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/sdab/

Core works with existing resources to provide targeted study design and biostatistics support to ITMAT/CTSA investigators.Services include protocol review, study design, proposal development, and performance of simple to potentially substantial complex analyses. SDAB integrates support available with HUP and CHOP Center for Human Phenomic Science (CHPSs), expertise and resources of faculty in Center for Clinical Epidemiology and Biostatistics / Department of Biostatistics and Epidemiology (CCEB/DBE), Biostatistics Analysis Center (BAC), and Biostatistics and Data Management Core (BDMC) at CHOP.

Proper citation: University of Pennsylvania Perelman School of Medicine ITMAT Study Design and Biostatistics Core Facility (RRID:SCR_022413) Copy   

•   Source: SciCrunch Registry

http://agl.tamu.edu/

Assists graduate students, staff and faculty launch, economize and expedite their research, especially when it involves DNA extraction and quality checks, targeted genotyping and DNA content analysis. Facilitates usage of complementary cores and assists with research planning and data analysis.AGL members have free lab access and reduced costs for services as well as one-on-one training and advising with AGL staff.

Proper citation: Texas A and M University AgriGenomics Laboratory Core Facility (RRID:SCR_022533) Copy   

•   Source: SciCrunch Registry

https://www.biotech.cornell.edu/core-facilities-brc/facilities/transcriptional-regulation-expression-facility-trex

Facility offers genomics profiling services including RNAseq, small RNA sequencing, and ATACseq.

Proper citation: Cornell University Biotechnology Resource Center Transcriptional Regulation and Expression Core Facility (RRID:SCR_022532) Copy   

•   Source: SciCrunch Registry

http://www.sylvester.org/OGSR

Provides access to technologies and services for study of genomics and epigenomics of cancer, in addition to providing technical expertise for project design, trouble shooting and pre and post award support. Services include next generation sequencing, single cell genomics, spatial genomics, gene expression assays and molecular quantitation, services for sample extraction and QC.

Proper citation: University of Miami Sylvester Onco Genomics Shared Resource Core Facility (RRID:SCR_022502) Copy   

•   Source: SciCrunch Registry

https://www.med.unc.edu/genomics/about/

Full service sequencing facility to assist with genetic and genomic research. Part of Integrated Genomics Cores. Offers comprehensive library services, NextGen sequencing and alternative technologies including long reads. Offers library preparations and multiple sequencing platforms including MiSeq, HiSeq, NovaSeq, NextSeq, BioNano, Oxford Nanopore. Services also include using techniques and data analyses via sister core BARC.

Proper citation: UNC School of Medicine Integrated Genomics Cores High Throughput Sequencing Core Facility (RRID:SCR_022620) Copy   

•   Source: SciCrunch Registry

https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/core-facilities/radcore

Clinical Imaging Core Service Center includes RADCORE, Tumor Response Assessment (TRAC) and Research imaging guided biopsies cores. Supports cancer clinical trials. RADCORE staff include clinical research professionals with range of expertise in imaging based clinical research protocols and offers services in consultation, management of research protocols and Radiology IND/IDE support office. Tumor Response Assessment Core (TRAC) team of Radiologist is skilled in evaluating tumor response imaging assessments for patients enrolled in cancer clinical trials being conducted at UPHS. Research imaging guided biopsies Interventional Radiology and technical staff provides consultation to define biopsy protocol and pathology tissue collection.

Proper citation: University of Pennsylvania Perelman School of Medicine Clinical Imaging Service Center Core Facility (RRID:SCR_022487) Copy   

•   Source: SciCrunch Registry

https://sites.google.com/ucsc.edu/mal/

Operated by Institute of Marine Sciences with support from UCSC Division of Physical and Biological Sciences. Available to UCSC and University of California marine and coastal research community.Provides equipment including Shimadzu TOC-VCPH TC/TN analyzer,Dionex ICS-2000 Ion Chromatograph,UIC Carbon Coulometer Analyzer, Perkin-Elmer AAnalyst 100 Atomic Absorption Spectrophotometer, Thermo Genesys 10S UV-Visible Spectrophotometer, Turner Designs 10-AU Field Fluorometer, Turner Designs TD-700 Lab Fluorometer, Turner Designs TD-20/20 Luminometer,Lachat QuikChem 8000 Flow Injection Analyzer, Guildline 8410 PortaSal Salinometer, Labconco Freeze Dryer.

Proper citation: University of California at Santa Cruz Marine Analytical Laboratory Core Facility (RRID:SCR_022480) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/small-animal-imaging/miti/index.html

Core provides intravital imaging equipment to acquire advanced descriptive and quantitative data for imaging studies. Includes Olympus FVMPE-RS advanced multiphoton microscope, multichannel, multiphoton excitation system specifically tailored for intravital and deep tissue imaging.System is additionally equipped with 458 and 588 nm stimulation laser lines for photobleaching, light stimulation and/or photoactivation of various fluorescent or caged constructs. Uses Spectra-Physics InSight X3 dual-line, tunable multiphoton laser for ultrafast, multichannel imaging.Available Neurotar Mobile Home Cage allows researchers to integrate real-time imaging with behavioral/locomotion tracking. Offers training and access to imaging system, support in design of experimental procedures, acquisition of image data, and analysis of acquired images.

Proper citation: University of Nebraska Medical Center Multiphoton Intravital and Tissue Imaging Core Facility (RRID:SCR_022478) Copy   

•   Source: SciCrunch Registry