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https://go.osu.edu/ltbsr

Human tissue biorepository offering procurement and distribution services for samples obtained from patients with hematologic malignancies.

Proper citation: Ohio State University Wexner Medical Center Leukemia Tissue Bank Core Facility (RRID:SCR_023052) Copy   

•   Source: SciCrunch Registry

https://vivariumandtransgenicscore.vai.org/

Provides genetically modified animal models for our collaborators. For preexisting models provides rederivation or reconstitution for purpose of importing animals into Vivarium barrier. In the absence of preexisting models core works closely with partnering labs to generate their ideal mutation de novo, often using CRISPR technology. Usually beginning with a brief consultation, this process involves discussing factors such as ideal background strain, molecular methods for optimizing the intended genetic change, mutation induction strategies, screening approaches and eventual QC of the new mutant line with the overall goal of giving our collaborators a fully informed, realistic picture of their projects timeframe, pitfalls and workflow. Core provides mouse sperm and embryo cryopreservation services for purpose of archiving and distributing valuable lines. Institute is an AAALAC-accredited facility. All procedures are conducted according to the NIH Guide for the Care and Use of Laboratory Animals.

Proper citation: Van Andel Institute Transgenic Core Facility (RRID:SCR_022914) Copy   

•   Source: SciCrunch Registry

https://www.cshl.edu/research/cancer/microscopy/

Provides access to microscopes, technical advice and expertise in preparing cells or tissues for immunofluorescence/confocal microscopy, live cell imaging, super resolution imaging, transmission electron microscopy, and immunoelectron microscopy.

Proper citation: Cold Spring Harbor Laboratory Microscopy Shared Resource Core Facility (RRID:SCR_023023) Copy   

•   Source: SciCrunch Registry

https://www.cores.emory.edu/escc/

Core is supported by Georgia Clinical and Translational Science Alliance and Emory University School of Medicine. One of Emory Integrated Core Facilities (EICF). Offers services for generating induced pluripotent stem cells from human somatic cells for research.

Proper citation: Emory University Emory Stem Cell Core Facility (RRID:SCR_023264) Copy   

•   Source: SciCrunch Registry

https://teamhubottawa.com/

Core research facilities include BioImaging Research Node which houses commercial and custom imaging systems and is focused on optical imaging; Tissue Engineering and Biomaterials Testing Research Node equipped with microfluidics 3D bioprinter and mechanical testers, which facilitate development of artificial 3D biological tissue models and biomechanical testing of different biomaterials and biomedical samples; Biochemistry and Molecular Biology Research Node which houses hypoxia chamber and systems for characterization and quantification of proteins, peptides, and nucleic acids; Cellular Biology Research Node to support development and use of 3D tissue models.It houses instruments including flow cytometer for phenotyping and performing functional testing of cells and bacteria, Seahorse Analyzer for evaluation of metabolic activity of cells, and Incucyte for live cell imaging of cells and tissues in culture.

Proper citation: Carleton University Tissue Engineering and Applied Materials Hub Core Facility (RRID:SCR_022968) Copy   

•   Source: SciCrunch Registry

https://research.arizona.edu/facilities/search/imaging-cores-electron-life-sciences-north

Electron facility provides full Biological Transmission Electron Microscopy related research, consultation, and imaging services.Offers services using FEI Tecnai Spirit Transmission Electron Microscope.

Proper citation: University of Arizona Imaging Cores Electron Core Facility (RRID:SCR_023279) Copy   

•   Source: SciCrunch Registry

https://www.cores.emory.edu/bcc/

Core is housed in the Department of Biostatistics and Bioinformatics in the Rollins School of Public Health of Emory University. BCC personnel are available for discussion at all stages of research, including: preparation of grants and contracts, assistance in analyzing and presenting research data, and statistical review of manuscripts in publication process. Provides access to computer hardware and software and personnel with expertise in using major statistical, graphics, and data management packages. Offers services from database development, implementation, and maintenance to production of publication quality graphic and tabular material.BCC tasks are classified into short term tasks that can be completed within three to six months with clear deliverables.

Proper citation: Emory University Biostatistics Collaboration Core Facility (RRID:SCR_023521) Copy   

•   Source: SciCrunch Registry

https://www.lifespan.org/centers-services/molecular-pathology-core-laboratory

Core of COBRE Center at department of Pathology located on sixth floor of Aldrich building at Rhode Island Hospital.Provides services, instrumentation, training and support. Equipment includes ArcturusXT laser capture microdissector, Stratagene MX3005p realtime PCR instrument, BioRad iCycler, Agilent Bioanalyzer, Olympus fluorescence-capable microscope with image analysis software, Ventana Discovery immunohistochemistry processor, microtome, cryostat, Beecher tissue arrayer and Aperio ScanScope.Tissue bank has 40 cu ft of ultra-low freezer space and provides human tumor tissue samples to all interested investigators who have received IRB approval for academic testing and research.Services include Tissue Sample Processing,Histology,Immunohistochemistry,Digital slide scanning by Aperio ScanScope,Tissue Microarrays,DNA/RNA extraction, Microdissection,Macrodissection verification by pathologist,Digital image analysis,Visium Spatial Gene Expression Assay,RNAscope Assay,Enzyme Linked Immunosorbent Assays (ELISAs),Technical assistance,Pathologist consultation,Technical assistance, Equipment use and training.

Proper citation: Rhode Island Hospital Molecular Pathology Core Facility (RRID:SCR_023490) Copy   

•   Source: SciCrunch Registry

https://hpcc.stanford.edu/

Academic cost recovery center, operates number of HPC clusters to enable larger simulations, deeper analyses, and faster computation times than are possible using computers available to individual researchers. Provides mass data storage and archival systems to store data.

Proper citation: Stanford University High Performance Computing Center Core Facility (RRID:SCR_023411) Copy   

•   Source: SciCrunch Registry

https://www.crg.eu/en/programmes-groups/protein-technologies-unit

Provides technology platform to perform protein production and automated processes in context of biomolecular and biochemical screening assays.Through staff assisted screening, users have access to equipment including liquid handlers, plate readers and small molecule libraries.Unit is aimed at supporting the researchers of the CRG institute by purchasing, seeking and maintaining valuable stocks of clones and strains.

Proper citation: Centre for Genomic Regulation Protein Technologies Unit Core Facility (RRID:SCR_023376) Copy   

•   Source: SciCrunch Registry

https://www.crg.eu/en/programmes-groups/tissue-engineering-unit-0

Provides latests technologies for stem cell biology, stem cell differentiation, organoid formation and induced pluripotent stem cells.Tissue Engineering platform works in collaboration with Biomolecular Screening and Protein Technologies Unit to provide CRISPR/Cas9 genome editing technology service.Unit also includes Histology In-house Service (only for PRBB residents) provides histopathological analysis required for analysing tissues from research performed in in vivo models. Histology In-house Service performs and optimizes histological processing and analysis of tissue, from experimental animal models and human origin.Provides mentoring and training in common histological techniques.

Proper citation: Centre for Genomic Regulation Tissue Engineering Unit Core Facility (RRID:SCR_023375) Copy   

•   Source: SciCrunch Registry

https://cores.utah.edu/cell-imaging/

Core offers services, training and provides access to optical microscopes and imaging.Offers collaboration for complex projects.

Proper citation: University of Utah Cell Imaging Core Facility (RRID:SCR_023496) Copy   

•   Source: SciCrunch Registry

https://www.crg.eu/en/programmes-groups/genomics-unit

Supports next generation sequencing technologies and provides several next generation sequencing instruments. Several high-throughput technologies have been implemented to assess differential expression, inter-individual genetic variation, microRNA discovery, genome sequencing, targeted resequencing, epigenetic profiling and identification of binding sites of DNA or RNA-associated proteins.

Proper citation: Centre for Genomic Regulation Genomics Unit Core Facility (RRID:SCR_023374) Copy   

•   Source: SciCrunch Registry

https://www.crg.eu/en/programmes-groups/crgupf-flow-cytometry-unit

Flow cytometry studies optical parameters emitted by particles (cells, cell fractions). Flow cytometers can study a series of parameters of individual particles simultaneously, quickly and on a large number of individualized particles in suspension. Flow cytometers use lasers as a source of light excitement; therefore, it must be possible to mark the particles with one or more fluorescent substances. Information is also collected regarding the size and structural complexity of each particle. This multiparameter study of each particle enables us to analyse subpopulations in complex samples through electronic sorting. Some cytometers are also equipped with sorting and collection modules for particles of interest. The most important applications of flow cytometry include those relating to the study of cell surface receptors, nuclear and cytoplasmic antigens, DNA content, enzyme activity, cell integrity and membrane permeability and calcium flows. The Unit currently hosts five analyzers and two sorters, and is therewith the largest Becton Dickinson site in Spain. The sorters are operated by the facility personnel, who also support the users in experimental design and data analysis. The analyzers are operated by the users themselves, after they have been trained. The facility personnel helps with the experimental design and supervises and monitors the experiments when necessary.

Proper citation: Centre for Genomic Regulation Flow Cytometry Unit Core Facility (RRID:SCR_023372) Copy   

•   Source: SciCrunch Registry

https://www.pharmacy.umaryland.edu/centers/massspec/

Provides access to cutting edge technologies in mass spectrometry, methodology, and instrumentation. Provided expertise include the fields of Chemical Biology,Pharmaceutical Biology,Cancer Biology,Microbial Biology,Infectious Disease,Metabolic Disease,Chronic Pain Research,Quantitative Biosciences, Drug Discovery and Drug Development,Translational and Regulatory Sciences,Nanotechnology,.Bioinformatics and Technology Development

Proper citation: University of Maryland School of Pharmacy Mass Spectrometry Center Core Facility (RRID:SCR_023493) Copy   

•   Source: SciCrunch Registry

https://www.cores.emory.edu/eigc/

Core helps investigators use the latest genomics technologies in their research.

Proper citation: Emory University Emory Integrated Genomics Core Facility (RRID:SCR_023529) Copy   

•   Source: SciCrunch Registry

https://stanford.ilabsolutions.com/service_center/show_external/21/biomaterials-and-advanced-drug-delivery-bioadd-laboratory

Provides creation of biomaterials and drug delivery agents, expertise toward designing and analyzing biomaterials, development of drug delivery devices and formulations, pharmacokinetic and pharmacodynamic studies, and development of materials for biomedical applications.

Proper citation: Stanford University Biomaterials and Advanced Drug Delivery Laboratory Core Facility (RRID:SCR_023406) Copy   

•   Source: SciCrunch Registry

https://www.cores.emory.edu/eimlc/

Provides quantitative analysis of lipids and soluble metabolites using cutting-edge mass spectrometry methods as a service to both clinical and basic biomedical research efforts. We deliver quantitative lipidomics and metabolomics analyses on samples from a wide variety of biological matrices, e.g. blood, serum, plasma, solid tissues, fecal/urine samples, cell extracts, etc., to support both clinical and basic research efforts.

Proper citation: Emory University Emory Integrated Metabolomics and Lipidomics Core Facility (RRID:SCR_023527) Copy   

•   Source: SciCrunch Registry

https://web.stanford.edu/group/chem-optics/

Houses optical spectroscopy instruments including Fluorolog 3 Fluorimeter,Vertex 70 FTIR with RAM II Raman accessory, Cary 6000i UV/Vis/NIR Spectrometer.

Proper citation: Stanford University Chemistry Department Optics Core Facility (RRID:SCR_023405) Copy   

•   Source: SciCrunch Registry

https://med.stanford.edu/lcgm.html

Provides support and services to clinical investigators including consulting, technology transfer, process and analytical development, clinical manufacturing and regulatory affairs.

Proper citation: Stanford University School of Medicine Laboratory for Cell and Gene Medicine Core Facility (RRID:SCR_023403) Copy   

•   Source: SciCrunch Registry