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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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University of Chicago Digestive Diseases Research Core Center Administrative Core Resource Report Resource Website |
University of Chicago Digestive Diseases Research Core Center Administrative Core (RRID:SCR_015602) | access service resource, service resource, core facility | Core that has oversight of the other four cores of University of Chicago's Digestive Disease Research Core Center and determines the center's overall direction. | administrative, digestive disease research |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Chicago Digestive Diseases Research Core Center is organization facet of: University of Chicago Digestive Diseases Research Core Center |
digestive disease | NIDDK P30 DK042086 | Available to the research community | SCR_015602 | 2026-07-28 09:44:06 | 0 | ||||||||
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University of Chicago Digestive Diseases Research Core Center Host-Microbe Core Resource Report Resource Website 1+ mentions |
University of Chicago Digestive Diseases Research Core Center Host-Microbe Core (RRID:SCR_015603) | access service resource, service resource, core facility | Core that consists of two components: The Enteric Microbiology and The Gnotobiotic Mouse components. The Enteric Microbiology component offers novel screening and advanced technologies for compositional and functional profiling of the resident microbial communities in the gastrointestinal tract. The Gnotobiotic Mouse component enables investigators to study the effects and causal role of specific microorganisms or profiles in vivo. | host microbe, Enteric Microbiology, Gnotobiotic Mouse, inflammatory bowel diseases |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Chicago Digestive Diseases Research Core Center is organization facet of: University of Chicago Digestive Diseases Research Core Center |
digestive disease | NIDDK P30 DK042086 | Available to affiliated researchers, Available to DDRCC researchers | SCR_015603 | 2026-07-28 09:43:53 | 1 | ||||||||
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Mayo Clinic O'Brien Urology Center Imaging Core Resource Report Resource Website |
Mayo Clinic O'Brien Urology Center Imaging Core (RRID:SCR_015454) | access service resource, service resource, resource, core facility | Core that provides renal stone imaging and analysis techniques, including dual energy CT data acquisition and analyses, dual energy material decomposition analysis, high-resolution image reconstruction and analysis, and coordination of micro-CT scanning and data analysis. | renal stone imaging, renal stone analysis, urological imaging |
is listed by: NIDDK Information Network (dkNET) has parent organization: Mayo Clinic has parent organization: Mayo Clinic O'Brien Urology Center is organization facet of: Mayo Clinic O'Brien Urology Center |
NIDDK U54DK100227 | Available to the research community | SCR_015454 | 2026-07-28 09:44:04 | 0 | |||||||||
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Joslin Diabetes Center Molecular Phenotyping and Genotyping Core Resource Report Resource Website |
Joslin Diabetes Center Molecular Phenotyping and Genotyping Core (RRID:SCR_015733) | access service resource, service resource, core facility | Core facility that supports the study of molecular mechanisms of disease by providing equipment, expertise, and services in molecular phenotyping, including nucleic acid sequence analyses, gene expression, and other "omics" analyses, which would be too specialized or costly for individual laboratories to perform independently. Formerly known as the Advanced Genomics and Genetics Core, the Molecular Phenotyping Core is newly-named in recognition of the expansion of its analytical capacities to reflect not only genetic and genomic analyses but also metabolic phenotyping. | molecular phenotype, genotype, core facility, joslin diabetes center, diabetes |
is listed by: NIDDK Information Network (dkNET) has parent organization: Joslin Diabetes Center |
Available to affiliated researchers | SCR_015733 | Molecular Phenotyping and Genotyping Core | 2026-07-28 09:44:00 | 0 | |||||||||
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Mayo Clinic O'Brien Urology Center Urine Phenotyping Core Resource Report Resource Website |
Mayo Clinic O'Brien Urology Center Urine Phenotyping Core (RRID:SCR_015455) | access service resource, service resource, resource, core facility | Core that aims to increase understanding of the factors that modulate the interface of urinary proteins and crystals, and hence their subsequent interaction with other crystals or cells. Its services include quantification of urinary components of the supersaturation profile, quantification of urinary inhibitor activity, quantification of known urinary macromolecular inhibitors, and application of differential proteomics to urine samples of stone forming and control populations. | urine phenotyping, urinary protein, urinary crystal, renal stone disease |
is listed by: NIDDK Information Network (dkNET) has parent organization: Mayo Clinic has parent organization: Mayo Clinic O'Brien Urology Center is organization facet of: Mayo Clinic O'Brien Urology Center |
NIDDK U54DK100227 | Available to the O'Brien Urology Research Center community | SCR_015455 | 2026-07-28 09:43:50 | 0 | |||||||||
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University of Michigan Center for Gastrointestinal Research Molecular Biology Core Resource Report Resource Website |
University of Michigan Center for Gastrointestinal Research Molecular Biology Core (RRID:SCR_015610) | access service resource, service resource, core facility | Core whose services include the following programs: Transgenic Rodent Program, Genome Editing Program, Viral Vector Program, and Integrated Genomics Program. | Molecular Biology, genome editing, transgenic rodent, viral vector, integrated genomics |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Michigan Center for Gastrointestinal Research is organization facet of: University of Michigan Center for Gastrointestinal Research |
digestive disease | NIDDK P30 DK034933 | Available to affiliated researchers | SCR_015610 | 2026-07-28 09:44:06 | 0 | ||||||||
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University of Washington Nutrition and Obesity Research Center Adipose Tissue and Obesity Core Resource Report Resource Website |
University of Washington Nutrition and Obesity Research Center Adipose Tissue and Obesity Core (RRID:SCR_015481) | access service resource, service resource, resource, core facility | Core that provides affiliated investigators with assistance for in vivo and in vitro studies in both subcutaneous and visceral human adipose tissue. Body and liver fat measurement by DXA and MRI are also provided, as is support for translational studies that assist investigators in the design conduct of clinical obesity research. | in vivo study, in vitro study, subcutaneous human adipose tissue, visceral human adipose tissue, liver fat, translational study, clinical obesity research |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Washington; Seattle; USA has parent organization: University of Washington Nutrition and Obesity Research Center is organization facet of: University of Washington Nutrition and Obesity Research Center |
Obesity | NIDDK P30DK035816 | Available to the research community, Fee for service | SCR_015481 | 2026-07-28 09:44:04 | 0 | ||||||||
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Rare and Atypical Diabetes Network Resource Report Resource Website 1+ mentions |
Rare and Atypical Diabetes Network (RRID:SCR_024732) | RADIANT | disease-related portal, data or information resource, database, topical portal, portal | Portal dedicated to characterizing, discovering and defining rare and atypical forms of diabetes. Network of universities, hospitals and clinics across the United States dedicated to better understanding atypical diabetes. Team of academic institutions and scientists collaborates with physicians and healthcare groups to identify those with atypical diabetes and learn more about their health. | USA, universities network, hospitals and clinics network, characterizing atypical diabetes, discovering atypical diabetes, defining atypical diabetes, rare and atypical forms of diabetes, atypical diabetes, |
is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Central Repository |
rare and atypical forms of diabetes, Diabetes | NIDDK | Restricted | SCR_024732 | Rare and Atypical DIAbetes NeTwork | 2026-07-28 09:46:12 | 2 | ||||||
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All of Us Resource Report Resource Website 10+ mentions |
All of Us (RRID:SCR_027032) | data or information resource, database, portal | Portal stores health data from participants from across the United States. Provides interactive Data Browser where anyone can learn about the type and quantity of data that All of Us collects. Users can explore aggregate data including genomic variants, survey responses, physical measurements, electronic health record information, and wearables data. | health data, United States data, genomic variants, survey responses, physical measurements, electronic health record information, |
is listed by: NIDDK Information Network (dkNET) is related to: Broad Institute Genomics Platform |
Free, Freely available, | SCR_027032 | 2026-07-28 09:46:51 | 24 | ||||||||||
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Porphyria Consortium Resource Report Resource Website |
Porphyria Consortium (RRID:SCR_014379) | A consortium which includes five of the leading porphyria centers in the United States that provide expertise and experience in the diagnosis and treatment of patients with porphyria. The staff in each Center includes porphyria physicians, researchers, research coordinators, and technical/laboratory staff. Together with the American Porphyria Foundation, the Porphyrias Consortium enables a large scale collaborative effort to develop strategies and methods for diagnosis, treatment, and prevention of illness and disability resulting from these rare disorders. | diagnosis, treatment, porphyria, rare disorder |
is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources |
SCR_014379 | Porphyrias Consortium, The Porphyria Consortium | 2026-07-25 12:07:59 | 0 | |||||||||||
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CKD Biomarkers Consortium Resource Report Resource Website 1+ mentions |
CKD Biomarkers Consortium (RRID:SCR_014381) | A consortium which aims to promote the discovery and validation of biomarkers to advance the field of CKD research. The NIDDK CKD Biomarkers Consortium brings together investigators whose expertise includes clinical nephrology, epidemiology, molecular biology, genomics, proteomics, metabolomics, systems biology, laboratory medicine, biostatistics, and laboratory test verification and qualification. | validate, biomarker, niddk, epidemiology |
is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources has parent organization: NIDDK- National Institute of Diabetes and Digestive and Kidney Diseases Obesity Resources |
Investigators interested in collaborating with the CKD Biomarkers Consortium should contact Krista Whitehead | http://www.niddk.nih.gov/research-funding/research-resources/Pages/default.aspx | SCR_014381 | BioCon | 2026-07-25 12:08:03 | 8 | |||||||||
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T1D Exchange Resource Report Resource Website 10+ mentions |
T1D Exchange (RRID:SCR_014532) | commercial organization | Provides access to resources T1D researchers need to conduct clinical studies. Data sets from their clinic registry is openly available, as are new study results. They also offer use of T1D Discovery Tool, which allows users to search different fields from registry data, and T1D Exchange Biobank, which offers specimen types such as serum, plasma, white blood cells, DNA, and RNA. | portal, dataset, type 1 diabetes, t1d, clinical, study, registry, data |
is listed by: NIDDK Information Network (dkNET) is related to: Type 1 Diabetes Knowledge Portal is parent organization of: T1D Exchange Biobank |
Type 1 diabetes, Diabetes | grid.461811.b | https://ror.org/016jvas21 | SCR_014532 | T1D Exchange Inc. | 2026-07-25 12:08:04 | 12 | |||||||
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EuReGene Resource Report Resource Website |
EuReGene (RRID:SCR_014516) | group | A European organization primarily concerned with the study of renal disorders. The organization is working towards discovering the genes responsible for renal development, renal disease and the related proteins and their actions. EuReGene consists of a consortium of scientists, clinicians, and SME partners that study functional genomics and their application in kidney research. | renal, europe, renal development, renal disease, renal proteins, functional genomics |
is listed by: GUDMAP Ontology is listed by: NIDDK Information Network (dkNET) |
European Union FP6 | SCR_014516 | 2026-07-25 12:08:04 | 0 | ||||||||||
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Stem Cell Genome Anatomy Projects Resource Report Resource Website |
Stem Cell Genome Anatomy Projects (RRID:SCR_014517) | SCGAP | group | A research organization which aims to conduct a variety of stem cell research projects. These projects include: to CD phenotype the human prostate and bladder using a confocal microscopy, to CD the phenotype of the mouse prostate and bladder, to profile samples of basal and stromal cells using uncultured cells, to confirm cell-type specific expression of genes that were identified by array analysis, and to create a database with the resulting database. | stem cell, research, cd, human phenotype, human prostate, bladder, confocal microscopy, mouse prostate, array analysis, |
is listed by: GUDMAP Ontology is listed by: NIDDK Information Network (dkNET) |
NIDDK | SCR_014517 | SCGAP Urologic Epithelial Stem Cells Project | 2026-07-25 12:08:06 | 0 | ||||||||
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NIH Common Fund Resource Report Resource Website 10+ mentions |
NIH Common Fund (RRID:SCR_012790) | NIH Common Fund | government granting agency | Supports cross-cutting, trans-NIH programs that require participation by at least two NIH Institutes or Centers (ICs) or would otherwise benefit from strategic planning and coordination. The requirements for the Common Fund encourage collaboration across the ICs while providing the NIH with flexibility to determine priorities for Common Fund support. To date, the Common Fund has been used to support a series of short term, exceptionally high impact, trans-NIH programs known collectively as the NIH Roadmap for Medical Research. The Common Fund is coordinated by the Office of Strategic Coordination, one of the six offices of the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI) within the Office of the Director. The intent of NIH Common Fund programs is to provide a strategic and nimble approach to address key roadblocks in biomedical research that impede basic scientific discovery and its translation into improved human health. In addition, these programs capitalize on emerging opportunities to catalyze the rate of progress across multiple biomedical fields. Common Fund programs are expected to transform the way a broad spectrum of health research is conducted. Initiatives that comprise Common Fund programs are intended to be catalytic in nature by providing limited term investments in strategic areas to stimulate further research through IC-funded mechanisms. |
is listed by: NIDDK Research Resources is listed by: NIDDK Information Network (dkNET) has parent organization: National Institutes of Health is parent organization of: Common Fund Protein Capture Reagents is parent organization of: Roadmap Epigenomics Project |
nlx_146248 | SCR_012790 | NIH Roadmap for Medical Research, NIH Roadmap Initiative | 2026-07-25 12:07:36 | 12 | |||||||||
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Congressionally Directed Medical Research Program Resource Report Resource Website 10+ mentions |
Congressionally Directed Medical Research Program (RRID:SCR_006456) | CDMRP | nonprofit organization | Fund the best research to eradicate diseases and support the warfighter to benefit the American Public. They promote innovative research, recognizing untapped opportunities, creating partnerships, and guarding the public trust. Research Program topics include: * Amyotrophic Lateral Sclerosis * Autism * Bone Marrow Failure * Breast Cancer * Defense Medical Research and Development Program * Duchenne Muscular Dystrophy * Gulf War Illness * Lung Cancer * Multiple Sclerosis * Neurofibromatosis * Ovarian Cancer * Peer Reviewed Cancer * Peer Reviewed Medical * Peer Reviewed Orthopaedic * Prostate Cancer * Psychological Health / Traumatic Brain Injury * Spinal Cord Injury * Tuberous Sclerosis Complex | grant, funding, one mind tbi, one mind ptsd, medical, medical research, psychological health, orthopedic, peer review, biomedical |
is related to: NIDDK Information Network (dkNET) has parent organization: U.S. Department of Defense |
Amyotrophic Lateral Sclerosis, Autism, Bone marrow failure, Breast cancer, Duchenne muscular dystrophy, Gulf War Illness, Lung cancer, Multiple Sclerosis, Neurofibromatosis, Ovarian cancer, Cancer, Prostate cancer, Traumatic brain injury, Spinal cord injury, Tuberous sclerosis complex | United States Department of Defense | nif-0000-00443, grid.496791.4, Crossref funder ID: 100000090, ISNI: 0000 0000 9367 6288, Wikidata: Q45134126 | https://ror.org/03g2zjp07 | SCR_006456 | DOD CDMRP | 2026-07-25 12:06:21 | 48 | |||||
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Urologic Diseases in America Resource Report Resource Website |
Urologic Diseases in America (RRID:SCR_006644) | UDA | human subject report | A report incorporating current and retrospective data on all aspects of the epidemiology, practice patterns, costs, and impact of urologic diseases in the United States and is intended for use by public officials, nongovernment organizations, the media, academic researchers, health professionals, and the public. The UDA compendium consists of data tables annotated in chapters that amplify the data analyses. The objectives of the UDA project include: secondary data analyses of: changes in the overall healthcare burden for individual urologic diseases, in physician practice patterns for each urologic disease, and in demographics of persons with urologic disease, the impact of specific urologic diseases, especially diseases of the prostate, on the minority populations of the U.S., and documentation of new and evolving therapies for urologic disease and their cost. | epidemiology, urology, diagnosis, risk factor, prevalence, treatment, urological disease, report, practice pattern, data table, data analysis, prostate |
is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources has parent organization: National Kidney and Urologic Diseases Information Clearinghouse |
Urologic disease | National Institute of Diabetes and Digestive and Kidney Diseases | Public, Acknowledgement requested | nlx_152720 | SCR_006644 | Urologic Diseases in America Compendium, UDA Compendium | 2026-07-25 12:06:27 | 0 | |||||
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National Library of Medicine Resource Report Resource Website 100+ mentions |
National Library of Medicine (RRID:SCR_011446) | NLM | government granting agency | NLM collects, organizes, and makes available biomedical science information to scientists, health professionals, and the public. The Library's Web-based databases, including PubMed/Medline and MedlinePlus, are used extensively around the world. NLM conducts and supports research in biomedical communications; creates information resources for molecular biology, biotechnology, toxicology, and environmental health; and provides grant and contract support for training, medical library resources, and biomedical informatics and communications research. Celebrating its 175th anniversary in 2011, the National Library of Medicine (NLM), in Bethesda, Maryland, is a part of the National Institutes of Health, U.S. Department of Health and Human Services (HHS). Since its founding in 1836 as the library of the U.S. Army Surgeon General, NLM has played a pivotal role in translating biomedical research into practice. It is the world's largest biomedical library and the developer of electronic information services that deliver trillions of bytes of data to millions of users every day. Scientists, health professionals, and the public in the United States and around the globe search the Library's online information resources more than 1 billion times each year. The Library is open to all and has many services and resources for scientists, health professionals, historians, and the general public. NLM has over 17 million books, journals, manuscripts, audiovisuals, and other forms of medical information on its shelves, making it the largest health-science library in the world. In today's increasingly digital world, NLM carries out its mission of enabling biomedical research, supporting health care and public health, and promoting healthy behavior by: * Acquiring, organizing, and preserving the world's scholarly biomedical literature; * Providing access to biomedical and health information across the country in partnership with the 5,800-member National Network of Libraries of Medicine (NN/LM); * Serving as a leading global resource for building, curating and providing sophisticated access to molecular biology and genomic information, including those from the Human Genome Project and NIH Common Fund; * Creating high-quality information services relevant to toxicology and environmental health, health services research, and public health; * Conducting research and development on biomedical communications systems, methods, technologies, and networks and information dissemination and utilization among health professionals, patients, and the general public; * Funding advanced biomedical informatics research and serving as the primary supporter of pre- and post-doctoral research training in biomedical informatics at 18 U.S. universities. |
is used by: DisGeNET recommends: Brain Image Library recommends: Data Archive BRAIN Initiative recommends: OpenNeuro recommends: Brain Observatory Storage Service and Database (BossDB) recommends: CRCNS recommends: NCBI database of Genotypes and Phenotypes (dbGap) recommends: NIMH Data Archive recommends: ENCODE recommends: Genotype-Tissue Expression recommends: HMP Data Analysis and Coordination Center recommends: Illuminating the Druggable Genome recommends: Kids First Data Resource Portal recommends: HMS LINCS Database recommends: Metabolomics Workbench recommends: Patient-Reported Outcomes Measurement Information System recommends: Cancer Nanotechnology Laboratory (caNanoLab) recommends: Cancer Imaging Archive (TCIA) recommends: Network Data Exchange (NDEx) recommends: eyeGENE recommends: National Eye Institute (NEI) Commons recommends: National Sleep Research Resource (NSRR) recommends: CardioVascular Research Grid (CVRG) recommends: AMP-AD Knowledge Portal recommends: National Archive of Computerized Data on Aging (NACDA) recommends: National Institute on Aging Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) recommends: Immune Tolerance Network TrialShare recommends: The Immunology Database and Analysis Portal (ImmPort) recommends: VectorBase recommends: Virus Pathogen Resource (ViPR) recommends: LONI Image and Data Archive recommends: NeuroImaging Tools and Resources Collaboratory (NITRC) recommends: Child Language Data Exchange System (CHILDES) recommends: Data and Specimen Hub (NICHD DASH) recommends: National Children's Study (NCS) Archive recommends: PhonBank recommends: Archive of Data on Disability to Enable Policy (ADDEP) recommends: National Addiction and HIV Data Archive Program (NAHDAP) recommends: Neuroscience Information Framework recommends: National Institute on Drug Abuse Center for Genetic Studies recommends: NIDA Data Share recommends: AphasiaBank recommends: FluencyBank recommends: NIDDK Central Repository recommends: NIDDK Information Network (dkNET) recommends: Nuclear Receptor Signaling Atlas recommends: Chemical Effects in Biological Systems (CEBS) recommends: Cell Image Library (CIL) recommends: PhysioNet recommends: Transporter Classification Database recommends: Biological General Repository for Interaction Datasets (BioGRID) recommends: Federal Interagency Traumatic Brain Injury Research Informatics System recommends: NeuroMorpho.Org recommends: Parkinson’s Disease Biomarkers Program Data Management Resource (PDBP DMR) recommends: The NINDS Human Cell and Data Repository (NHCDR) recommends: ClinicalTrials.gov recommends: dbSNP recommends: dbVar recommends: GenBank recommends: Gene Expression Omnibus (GEO) recommends: NCBI Sequence Read Archive (SRA) recommends: 1000 Functional Connectomes Project recommends: exRNA Atlas recommends: Accelerating Medicines Partnership Type 2 Diabetes Knowledge Portal (AMP-T2D) recommends: PeptideAtlas recommends: Zebrafish Information Network (ZFIN) recommends: FlyBase recommends: Database of Interacting Proteins (DIP) recommends: Mouse Genome Informatics (MGI) recommends: UniProt recommends: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) recommends: European Nucleotide Archive (ENA) recommends: Analysis, Visualization, and Informatics Lab-space (AnVIL) recommends: DNA DataBank of Japan (DDBJ) recommends: UniProtKB recommends: SPARC Portal is related to: CureHunter is related to: Entrez has parent organization: National Institutes of Health is parent organization of: MalariaWorld is parent organization of: GenNav is parent organization of: NIH Common Data Element Repository is parent organization of: MEDLINE is parent organization of: ClinicalTrials.gov is parent organization of: Developmental and Reproductive Toxicology Database is parent organization of: Directory of Health Organizations Online is parent organization of: Haz-Map: Occupational Exposure to Hazardous Agents is parent organization of: Hazardous Substances Data Bank is parent organization of: Drug Information Portal is parent organization of: NIH Data Sharing Repositories is parent organization of: MeSH is parent organization of: Unified Medical Language System is parent organization of: NCBI is parent organization of: MedlinePlus is parent organization of: RxNorm is parent organization of: Bibliography on Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing is parent organization of: Chemical Carcinogenesis Research Information System is parent organization of: International Toxicity Estimates for Risk is parent organization of: BLAST Assembled RefSeq Genomes is parent organization of: Cross-Sectional and Longitudinal Aging Study is parent organization of: OrbitProject is parent organization of: Household Products Database is parent organization of: Entrez Utilities is parent organization of: Epidemiology of Chronic Disease in the Oldest Old |
nlx_inv_1005117 | SCR_011446 | U.S. National Library of Medicine | 2026-07-25 12:07:14 | 391 | |||||||||
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Diabetes Prevention Type 1 Resource Report Resource Website |
Diabetes Prevention Type 1 (RRID:SCR_001467) | DPT-1 | biomaterial supply resource, material resource | Data set and biosepecimens of a multi-center clinical trial to determine if treatment with beta-cell antigens can delay the onset of Type 1 Diabetes Mellitus (Type 1 DM) in non-diabetic relatives of persons with Type 1 DM. Insulin is a well characterized antigen specifically produced by beta-cells, and it was used for this purpose in the initial DPT-1 studies. The protocol for high risk subjects uses daily subcutaneous insulin injections and an annual course of intravenous insulin treatment, while the protocol for intermediate risk subjects uses daily doses of insulin administered orally. Neither injected nor oral insulin at the doses used were observed to delay or prevent diabetes, although further studies are needed to test whether oral insulin can delay diabetes in people in the intermediate risk group with high titers of insulin autoantibodies. | beta cell antigen, insulin, prevention, onset, subcutaneous injection, oral, intravenous, treatment, randomized, controlled trial, drug therapy, delay |
is listed by: One Mind Biospecimen Bank Listing is listed by: ClinicalTrials.gov is listed by: NIDDK Information Network (dkNET) is listed by: Diabetes Research Centers |
Type 1 diabetes, Diabetes | NIDDK UC4 DK097835 | Free, Freely Available | nlx_152696 | https://www.niddkrepository.org/niddk/jsp/public/dataset.jsp#DPT-1 | SCR_001467 | Diabetes Prevention Trial--Type 1 (DPT-1) dataset, DPT-1 (The Diabetes Prevention Type 1) | 2026-07-25 12:12:22 | 0 | ||||
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Drug-Induced Liver Injury Network Resource Report Resource Website 1+ mentions |
Drug-Induced Liver Injury Network (RRID:SCR_001524) | DILIN | biomaterial supply resource, material resource | Prospective and retrospective registry of well-characterized cases of drug-induced liver disease. The goals of Network include the development of standardized procedures to identify and fully characterize bona fide cases of drug- and complementary and alternative medicines (CAM)-induced liver injury, and to conduct controlled, clinical studies that will include extensive collection of data, serum, DNA, and tissue specimens. Cases of liver injury due to herbal medications are also included. The network will also develop terminology and standardized definitions for DILI, and to develop causality assessment instruments that are sensitive, specific, and reproducible. DILIN is funded by a cooperative agreement and includes five clinical centers and a central data coordinating center. The research goals of DILIN are to: * Create a registry of carefully documented DILI cases * Identify clinical, immunological, and environmental risk factors for drug- and CAM-mediated hepatotoxicity * Create a bank of biological specimens consisting of DNA, plasma, and immortalized lymphocytes to facilitate detailed genetic analyses * Characterize the natural history of drug- and CAM-induced DILI for at least six months following enrollment * Develop the capability to recontact these individuals over an extended period of time so that additional studies exploring DILI mechanisms can be performed Two studies are being initiated by the network. In the Retrospective Study, the implicated drugs are restricted to isoniazid, phenytoin, combination clavulanic acid/amoxicillin, and valproic acid (Depakote), Nitrofurantoin, Trimethoprim-sulfamethoxazole, Minocycline, and Quinolone antibiotics. These drugs were chosen because they are frequently administered to patients not receiving other hepatotoxic drugs, making it easier to establish causality. Patients must be alive, and the date of onset of the DILI episode must be on or after January 1, 1994. In the Prospective Study, all incident cases of drug- and CAM-induced liver injury are being considered. Initial presentation to a healthcare professional must be within the previous six months. A detailed medication history of the implicated DILI drug together with all prescription, OTC, and herbal medications is being recorded. Liver and serological tests are being performed to characterize the injury and to exclude competing causes of liver injury. A blood sample is also being drawn for plasma storage and DNA isolation. These cases will be followed longitudinally to characterize the long-term effects of the DILI episode. For both studies, documented, clinically significant DILI must be recorded in the patient's medical charts so that a causal determination can be made. Patients will be excluded if they are unwilling or unable to provide a blood sample or participate in the genetics component. Children under two years of age at the time of enrollment are excluded due to blood-volume requirements. If you have patients who are eligible to participate in either study, please contact one the DILIN clinical sites. As a general policy, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) invites investigator-initiated research project applications for ancillary studies to ongoing, large-scale clinical trials, epidemiological studies, and disease databases supported by the Institute. These studies are focused on a wide range of diseases and conditions including diabetes, obesity, acute and chronic liver disease, chronic kidney disease, and benign prostatic hyperplasia, among others. | prescription drug, over-the-counter drug, alternative medicine, herbal product, supplement, serum, dna, tissue, blood, immortalized lymphocyte, drug, medication, quinolone antibiotic, isoniazid, phenytoin, clavulanic acid, amoxicillin, valproic acid, depakote, nitrofurantoin, trimethoprim-sulfamethoxazole, minocycline, diagnosis, hepatotoxicity, risk factor, genetic analysis |
is listed by: One Mind Biospecimen Bank Listing is listed by: NIDDK Information Network (dkNET) is listed by: Diabetes Research Centers has parent organization: Duke University; North Carolina; USA |
Liver injury, Hepatic injury, Drug-induced liver disease | NIDDK | Qualified investigators, Account required | nlx_152822 | https://dilin.dcri.duke.edu/ | SCR_001524 | 2026-07-25 12:12:21 | 5 |
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