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http://tuskegee.eagle-i.net/i/00000136-648c-c32f-ee37-018280000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core provides services and training in computational biology, bioinformatics, experimental design and statistical analysis to the RCMI researchers and the biomedical research community at Tuskegee University.

Proper citation: Tuskegee University Computational Biology and Bioinformatics - Biomedical Information Management Services (RRID:SCR_010065) Copy   

•   Source: SciCrunch Registry

http://alaska.eagle-i.net/i/0000012a-2506-a131-a68e-378080000000

Core facility that provides the following services: Biological sample processing service, Research subject private information management service. The Community Engagement and Clinical Support Core facilitates and supports community-based participatory research by drawing on local community knowledge and scientific expertise to implement and evaluate culturally valid and effective approaches to research in Alaska Native communities. The functions of the core include: * Facilitating and sustaining community/CANHR partnerships by engaging the community in all phases of the research process. * Supporting researchers in the development and implementation of linguistically and culturally appropriate research protocols. * Providing technical capacity to collect clinical measures and biological samples. * Processing all biological specimens collected in the field and maintaining a secure biological storage facility for CANHR investigators and Alaska Native participants. The CECS Core supports CANHR''s central theme of community-based participatory research through strong and sustaining community partnerships with Alaska Native people.

Proper citation: UAF Community Engagement and Clinical Support Core (RRID:SCR_010066) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-babb-5786-9cd7-d7e280000000

Core facility that provides the following services: Sequencing sample preparation service, Illumina sequencing service, Initial analysis of sequencing data, Next-generation sequencing data delivery. The NGSC offers ultra high throughput sequencing services for the Perelman School of Medicine research community. We offer library quality assessments, sequencing, and optional preliminary data analysis for a wide variety of experimental protocols including ChIP-seq, RNA-Seq, HITS-CLIP, miR-Seq, exome capture, and BIS-seq. We offer limited library preparation services, but can advise on library preparation techniques. We have two Illumina hiSeq2000s for large-scale sequencing and a MiSeq for sample evaluation or library testing. To get started, visit our website, create an account for yourself, then create a new experiment and we will contact you.

Proper citation: Penn Next-Generation Sequencing Core (RRID:SCR_010026) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000140-2b21-9c5c-6ba0-cf2f80000000

The Penn Regional Nanotechnology Facility (PRN) is a full-service center equipped with a wide range of state-of-the-art instrumentation for materials analysis. Nanoscale characterization of polymers, ceramics, composites, metals, electronics, and thin films is conducted using scanning, transmission, and scanning-transmission electron microscopes, atomic force microscopes, and ion scattering techniques. A wide range of specimen preparation equipment is used including cryo-ultramicrotomy, jet electrolytic polishing, mechanical dimpling, ion beam thinning, tripod polishing, vacuum evaporation, sputter-coating and replication. Both analog and digital output are produced and in-house hardware and software are available for a wide range of image and spectrum processing tasks and for the calculation/simulation of electron-beam specimen interactions and microscope performance. The Nanotech Facility is setup to accommodate both academic and corporate users. Users have the option of working with a staff member or they may take advantage of our comprehensive user training in order to work independently on the instrument of their choice. Please feel free to contact us for any questions or comments about our facility.

Proper citation: Penn Regional Nanotechnology Facility (RRID:SCR_010029) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013a-64b2-be79-01af-beb880000000

Core facility that provides the following services: Metabolomics profiling service. This core provides sophisticated analytical services based on liquid chromatography-mass spectrometry.

Proper citation: Penn Mass Spectrometry Molecular Profiling Core (RRID:SCR_009990) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013c-4084-fd89-f162-a2b280000000

The Small Animal Imaging Facility (SAIF) of the University of Pennsylvania provides multi-modality radiological imaging and image analysis for cells, tissues, and small animals. The SAIF combines state-of-the-art instrumentation and a nationally recognized staff to assist investigators with a wide range of imaging based experimental approaches. The SAIF currently provides a comprehensive suite of imaging modalities including: magnetic resonance imaging (MRI) and spectroscopy (MRS), optical imaging (including bioluminescence, fluorescence, and near-infrared imaging), computed tomography (CT), positron emission tomography (PET), single photon emission computed tomography (SPECT), and ultrasound (US). In addition, dedicated housing is available for mice and rats undergoing longitudinal imaging studies. Ancillary facilities and resources of the SAIF are devoted to chemistry, radiochemistry, image analysis and animal tumor models, including assistance with animal handling.

Proper citation: Penn Small Animal Imaging Facility (RRID:SCR_010030) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013f-5341-6a43-a468-831a80000000

Core facility that provides the following services: Contrast enhanced sonography, Quantitative analysis of images, Small animal ultrasound imaging, Blood flow velocity measurement, Tissue motion measurement. The Ultrasound Sub-Core of the SAIF offers an array of research services for pre-clinical research including quantitative image analysis and consultation. Our state-of-the-art ultrasound scanners are available as a resource for conducting your research studies. This rich resource for ultrasound imaging is available at nominal hourly fees for various categories of study. Ultrasound Research Services provides services to a host of groups working on diverse projects such as the measurement of angiogenesis, vascularity, tissue elasticity, the effects of various pharmaceuticals on these measures and more. Such research encompasses a variety of clinical areas including radiology, oncology, cardiology, gynecology, and hematology, among others.

Proper citation: Penn Small Animal Imaging Facility: Ultrasound Sub-Core (RRID:SCR_010034) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/research-cores/massively-parallel-sequencing-shared-resource-mpssr

As of January 1, 2024, the Integrated Genomics Laboratory is one shared resource comprising the former Massively Parallel Sequencing Shared Resource, the Gene Profiling Shared Resource, and the DNA Services Core. Please be aware that the reorganization is an ongoing process, particularly regarding our iLab integration.Provides RNA-sequencing for gene expression analysis, DNA resequencing for single nucleotide polymorphism discovery, DNA resequencing for copy number variation discovery, ChiP-sequencing for promoter analysis, DNA methylation analysis, De novo sequencing for unique genomes, Sequence capture service. Offers sequencing including genome resequencing, transcriptome analysis, miRNA analysis, and prometer analysis via ChIP-seq.

Proper citation: OHSU Massively Parallel Sequencing Shared Resource Core Facility (RRID:SCR_009984) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012f-c755-f030-a63c-45b480000000

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on December 6,2022. Core facility that provides the following services: Mouse breeding service, Behavioral testing procedures service, Mouse breeding. Three of the MARC''s research components (5, 6, and 8) include experiments with lines of mice bred to have special genetic traits. The animal core supports these components by purchasing, testing, breeding, maintaining, and distributing these animals within the center. The core will breed special mouse lines F1 and F2 that are descendents of C57BL/6J (B6) and DBA/2J (D2) inbred strains. For Components 5 and 6, the animal core will also produce independent sets of replicated mouse lines selected for high and low tendencies toward methamphetamine drinking and for high and low methamphetamine-induced sensitization. In addition, the core is developing new behavioral-testing procedures and maintaining a database that will track individual animals and post their trait data for all MARC investigators to utilize.

Proper citation: OHSU Methamphetamine Abuse Research Center Animal Core Component (RRID:SCR_009985) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/00000131-1efe-8036-a944-114f80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Use of IOIC facility, In vivo optical imaging training service. The IOIC is located in Cardiac Imaging Laboratory on the first floor of the Biomedical Research Building (BRB). The laboratory was established through a Shared Instrument Grant (PI: Michael Deininger) but is maintained through user fees. The core facility includes the IVIS Spectrum optical imaging camera housed in a light-tight housing, rat and mouse imaging platforms for multi-subject simultaneous acquisition, an integrated inhaled anesthesia system, and advanced analysis software. A key component of the IOIC is the ability to operate either independently or under the guidance and supervision of core personnel. Independent use of the system requires that investigators undergo training that is offered every 2 months or on an ad hoc basis. All analysis will be charged on an hourly basis and is graduated according to the level of service (independent or supervised).

Proper citation: OHSU In Vivo Optical Imaging Center (RRID:SCR_009982) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/idom/drc/cores/transmouse.html

Mouse core which generates transgenic and gene-targeted mouse lines for diabetes research.

Proper citation: Penn Diabetes Research Center Transgenic and Chimeric Mouse Core Facility (RRID:SCR_010036) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2512-fb79-c99c-aef680000000

Core facility that provides the following services: Brain MRI service. Researchers in the Neuroscience and Magnetic Resonance Research Program are using a research dedicated 3-Tesla scanner to study the human brain and brain diseases. Facilities: The Magnetic Resonance (MR) Processing Core serves the needs of researchers in the MR Research Facility at Queen''s Hospital. Specifically, the MR Image Processing Core provides image processing support, infrastructure development, methodological development and training; expertise is available.

Proper citation: UH Manoa RCMI Magnetic Resonance Image Processing Core (RRID:SCR_010037) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012a-24ff-956f-d994-629180000000

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on December 6,2022. Core facility that provides the following services: Immunological study design and implementation, Flow cytometry assays service, High-throughput analysis service, Economies-of-scale reagent purchasing, Flow cytometry sorting service. The CIU offers all the study organization and technical expertise developed at the (Louis) Picker Lab to researchers whose questions require obtaining and processing monkey immunological samples, and/or utilizing cytometry to assay phenotype of CFC/ICS information. The CIU was originally developed as part of the Bill & Melinda Gates foundation CAVD (Collaboration for AIDS Vaccine Discovery) consortium.

Proper citation: OHSU Immunology Support Core Cellular Immunology Unit (RRID:SCR_009980) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013a-74d2-3dad-d69a-d90d80000000

Core facility that provides the following services: Outpatient study facility access, iDXA scan service, Research specimen processing, Research specimen storage, NIH/Industry clinical trial support, Pharmacy laboratory access, Adipose biopsy, Patient assessment and monitoring, Metabolic testing service, Phlebotomy, Support for bone marrow biopsies. The Clinical and Translational Research Center (CTRC) has two main locations as well as satellite locations. The protocols cover a wide variety of research areas including: HIV, sleep disorders, cholesterol, obesity, diabetes, various cancers, arthritis, hypertension, renal disease, short bowel syndrome, and neonatal and surgical studies as well as new treatments for various diseases. The CTRCs service over 1200 inpatients and over 6000 outpatients a year. Research subjects range from premature infants to the elderly, with the majority of adults being seen at HUP. HUP Unit - Dulles Building: * 8 bed inpatient * 8 chair and 2 bed outpatient unit * metabolic kitchen * Scatterbed nursing services throughout hospital units including the ICUs, ED and operating rooms UPPMC Unit ? 1st Fl Mutch Building: * 18 outpatient treatment beds * metabolic kitchen CHOP Units: * 4 bed inpatient unit - 5 West Main * outpatient unit with 2 treatment rooms, 4 treatment chairs and a consultation room - Main 7 * Scatterbed nursing services in Newborn Nursery - Ravdin Building The nurse manager should be contacted prior to submitting a new protocol submission to the CTRC and discussions should continue throughout the start-up process.

Proper citation: Penn/CHOP CTRC Research Nurse Core (RRID:SCR_010040) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2512-4e7e-c99c-aef680000000

Core facility that provides the following services: Gene expression analysis service, SNP analysis service, Genotyping service. We conduct microarray-related experiments, including developing chips for pathogen discovery, evaluating RNA quality and test chips, processing RNA specimens, hybridizing microarray chips, scanning microarray chips and providing raw data for analysis.

Proper citation: UH Manoa RCMI Microarray Core Facility (RRID:SCR_010042) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013a-41e9-a318-01af-beb880000000

Core facility that provides the following services: Data management assistance, Biostatistical analysis assistance. The Study Design and Biostatistics (SDAB) Core works closely with existing resources to provide targeted study design and biostatistics support to ITMAT/CTSA investigators. The Core serves as a direct provider of services, including protocol review, study design, proposal development, and performance of simple to potentially substantial complex analyses. SDAB integrates the support available with the HUP and CHOP Clinical and Translational Research Centers (CTRCs), the expertise and resources of faculty in the Center for Clinical Epidemiology and Biostatistics / Department of Biostatistics and Epidemiology (CCEB/DBE), the Biostatistics Analysis Center (BAC), and the Biostatistics and Data Management Core (BDMC) at CHOP.

Proper citation: Penn/CHOP CTRC Study Design and Biostatistics Core (RRID:SCR_010043) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000139-a0f2-42bc-4778-6c3080000000

Core facility that provides the following services: Cell culture and tissue services, DNA isolation service, Cell culture and tissue services, Epstein Barr Virus (EBV) lymphocyte transformation service, Cell culture and tissue services, Fibroblast culture and cryopreservation service, Cell culture and tissue services, Specialized cell isolation service, Molecular biology services, microsatellite haplotyping service, Molecular biology services, mutation analysis service, Molecular biology services, Restriction fragment analysis service, Molecular biology services, RNA services, Molecular biology services, SNP genotyping service, Specimen Collection, Processing, and Point-of-Care services, Bedside tests by Bayer Rapid Point 400, Specimen Collection, Processing, and Point-of-Care services; Collection, processing and storage of specimens, Specimen Collection, Processing, and Point-of-Care services, Packaging and shipping of samples. The Translational Core Laboratory consists of the Specimen Collection, Processing and Point of Care, Biochemistry, Cell Culture/DNA Isolation, and Molecular Biology core laboratories. Laboratory testing is integrated across Penn and CHOP, and TCL services are provided at multiple physical locations at both Penn and CHOP. Penn location: first floor Smilow Center for Translational Research CHOP location: 804 Abramson Research Center (ARC)

Proper citation: Penn/CHOP CTRC Translational Core Laboratories (RRID:SCR_010044) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013a-4211-18b7-01af-beb880000000

Core facility that provides the following services: Clinical study support services. The Office of Human Subject Recruitment and Protection (OHSRP) provides consultation and guidance to the Penn research community on all issues related to adult and pediatric human subjects being seen through the CTRC facilities, including recruitment and protection. The role of the OHSRP is to champion the mission of the feasible, safe and ethical conduct of human subject research within the CTRC. The original Research Subject Advocate (RSA) was a position mandated by the National Center for Research Resources under the NIH and was defined in order to ensure that research was being conducted in ways that did not increase the risk associated with conducting studies. In April 2008, the CTSA Consortium Steering Committee approved and endorsed best practices, which serve to define the mission, scope, and model for research advocacy within the CTSA consortium. The OHSRP has advanced the role of the Research Subject Advocate (RSA) by adopting the 2008 best practices defined by the CTSA Consortium. The OHSRP operations are complementary to and integrative with existing entities at the institution to promote and facilitate safe and ethical conduct of human research. The OHSRA complements the University of Pennsylvania Office of Human Research (OHR) and Institutional Review Board (IRB) in support of ensuring the safety of individuals participating in health research. The OHSRP serves as a resource to the research community and to participants; has a voice in policy regarding research ethics, participants? rights, and research safety; and plays a role in the protection of human subjects and responsible conduct of research educational programs of the institution. The OHSRP has direct access to, an authority that can temporarily suspend a research activity based on ethical and safety concerns so that problems can be explored or resolved through proper procedures. This capacity enables preliminary intervention into problems that might not necessarily invoke an institutional review board (IRB) suspension. The OHSRP has a reporting pathway to institutional officials of appropriate authority and is free of conflict of interest.

Proper citation: Penn/CHOP Office of Human Subject Recruitment and Protection (RRID:SCR_010046) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-7c6f-afad-fbab-3b8480000000

The Cell Center Stockroom is a division of the Genetics Core Facilities (GCF). The GCF is a University service center, established in 1973 to provide consultation, training, and services in the areas of cell culture and hybridomas. Also, the GCF to provides a full range of cell culture media and molecular biology reagents needed by investigators to perform cell culture techniques in their own laboratories. The DNA Sequencing Facility, Genetic Diagnostic Laboratory and Transgenic/Chimeric Animal Facility are the remaining three divisions of the GCF. The Stockroom serves University of Pennsylvania investigators and affiliate institutions (Cancer Center, Chidren''s Hospital of Philadelphia, Hospital of the Unviersity of Pennsylvania, The Wistar Institute, Monell Chemical Senses Center, and Presbyterian Hospital) by coordinating relations with various suppliers of molecular biological research materials. This involves not only bulk purchasing of these products, but the negotiation of discounts and convenient delivery arrangements. There are over 1,400 products on-site for immediate delivery in the Stockroom. Special ordering of non-regularly stocked products is available from 24 bioreagent vendors with discounted pricing and overnight delivery. List of Stockroom Vendors: * Accutek Laboratories * Amaxa Biosystems * Ambion, Inc. * Applied Biosystems * Atlanta Biologicals * Bio-Rad Laboratories * Biowhittaker * Cell Center Services * Cell Signaling Technologies * Clontech Laboratories * Collaborative * Denville Scientific * Difco Laboratories * EMD Chemicals * Fermentas * Fisher (Thermo) Scientific * Fuji Film * GE/Amersham Bioscience * Gemini Bio-Products�� * Hyclone Laboratories * Integrated DNA Technologies * Invitrogen * ISC Bioexpress * Kodak * KPL, Inc. * Life Technologies * Lonz A* MediaTech * Millipore * New England Biolabs * Open Biosystems * Perkin Elmer Life Sciences * Promeg A* Qiagen * Rainin Instruments * Roche�� * Sigma-Aldrich * Stratagene/Agilent Technologies * TruMark Scientific * USB Corporation/Affymetrix * VWR International * Zen-Bio, Inc.

Proper citation: Penn Cell Center Stockroom (RRID:SCR_010003) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-ba8f-c231-9cd7-d7e280000000

Core facility that provides the following services: Cryopreservation, Clinical Cell and Vaccine Production Facility quality control and quality assurance services, Clinical Cell and Vaccine Production Facility quality control training, Conjugation of proteins or antibodies to magnetic beads and quality control, Clinical Cell and Vaccine Production Facility vaccine preparation service, Enrichment of lymphocytes or monocytes from apheresis collection, WBC, lymphocyte and monocyte count, Conversion of patient/donor plasma to serum, Depletion of cell subpopulation from apheresis or lymphocytes, Clinical Cell and Vaccine Production Facility quality control testing. The Clinical Cell and Vaccine Production Facility (CVPF) is a GMP facility accredited by the Foundation for the Accreditation of Cellular Therapy (FACT) and a Department of Pathology/Lab Medicine and NCI approved Abramson Cancer Center Shared Resource. The CVPF provides focused scientific, technical and regulatory support for investigator initiated investigational new drug applications (INDs) in cell and gene therapy. Under compliance of FDA 21 CFR Parts 210 and 211, the CVPF performs cell processing on a range of different cell types, to include bone marrow derived CD4+ and CD8+ T lymphocytes, dendritic cells, and marrow stromal cells (aka mesenchymal stem cells). In each of these cases, cells are expanded ex vivo with or without genetic modification to the cells before being reintroduced back into the patient, either alone or in combination with other therapies such as vaccines. The overall mission of the Clinical Cell and Vaccine Production Facility is to help translate insights into novel cellular therapies.

Proper citation: Penn Clinical Cell and Vaccine Production Facility (RRID:SCR_010007) Copy   

•   Source: SciCrunch Registry