Tools   Select Another Resource Report Type

http://harvard.eagle-i.net/i/0000012c-cca8-e37a-a061-4a6580000000

The Molecular Diagnostics Laboratory provides such research services as microRNA expression profiling, human cell line identity verification, mutation detection for clinical research studies, and specimen processing for clinical research studies to investigators at the Dana Farber Cancer Institute, as well as to investigators at other institutions. Consultation on experimental design and assistance with data analysis are also available.

Proper citation: DFCI Shannon McCormack Advanced Molecular Diagnostics Laboratory (RRID:SCR_009756) Copy   

•   Source: SciCrunch Registry

http://mbcf.dfci.harvard.edu

Core offers services for genomic next-generation sequencing library preparation, sequencing and analysis applications including RNAseq, ChIPseq, ATACseq, CRISPR screening, whole genome methylation profiling, targeted resequencing, single-cell RNAseq, exome sequencing, and more. Performs bioinformatics analysis such as integration of multi-omics datasets or specialized analyses. Genomics core technology platforms include Illumina NovaSeq6000, NextSeq500s, MiSeqs, MiniSeq. High throughput sample preparation is performed on Beckman Coulter Biomek FX and i7 systems. Low throughput samples are prepared by technical staff.

Proper citation: Dana-Farber Cancer Institute Molecular Biology Core Facility (RRID:SCR_009754) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012f-bbba-4d59-de5a-673e80000000

Core facility that provides the following services: Cell Sorting.

The Flow Cytometry Core Facility provides sterile sorting and analysis of samples in support of research at DFCI. The core has 2 high-speed cell sorters, the BD FACSAria II SORP and BD FACSAria IIu with up to 12-color simultaneous detection utilizing multi-laser platforms. Sample populations can be sterile sorted into a variety of tubes or plates. The BD FACSAria II SORP and BD FACSAria IIu are both equipped with the Automated Cell Deposition Unit (ACDU) for sterile sinlge cell sorting into 96, 384 micro titer plates. The core presently has 2 analyzers, the BD LSRFortessa SORP and BD LSRII with up to 12-color simultaneous detection utilizing multi-laser platforms. The BD LSR II is also equipped with an HTS(high throughput sampler) for analyzing samples directly from 96 well micro titer plates as well as being able to run 5ml tubes. The Facility staff is available to assist researchers with their sorting and analysis needs. Researchers who would like to utilize the analyzers are trained so that they can analyze their experiments independently. The staff will assist with data acquisition and analysis as well as interpretation. They will also assist in experiment design and implementation as well as troubleshooting. Training sessions are available for researchers who would like to run their sorting experiments independently.

Proper citation: DFCI Flow Cytometry Core Facility (RRID:SCR_009751) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-a164-eaea-55da-381e80000000

Core facility that provides the following services: Graphics services, All Research Related Photography.

Medical Arts Core DFCI offers complete services for Publications, Presentations and Advertising as follows: Custom/Computer Graphics illustrations, Design and Consulting full productions services, Photoshop training. Posters Productions/Brochure Printing on best selection of paper, canvas material and Backlit poster films. Lamination, LCD announcements creation and posting. Research Related Photography Equipment: * iMAC and PC computers * Posters printer * LCD electronic announcements TV units * Backlit Display units * Laminator * Scanner * Digital camera

Proper citation: DFCI Medical Arts Core Facility (RRID:SCR_009752) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-58a1-825b-55da-381e80000000

Core facility that provides the following services: Data collection, data entry and analysis, Database design, data management and process tracking, Qualitative data collection, management and analysis.

The Survey and Data Management Core (SDMC) provides efficient, high-quality survey data collection and management services and consultation to support the research needs of investigators and staff throughout the Harvard Medical research community. The Core, housed within the Center for Population Sciences at the Dana-Farber Cancer Institute, is dedicated to rigorous quantitative and qualitative survey data collection and management.

Proper citation: DFCI Survey and Data Management Core (RRID:SCR_009750) Copy   

•   Source: SciCrunch Registry

http://tumormetrics.org/

Core facility that provides the following services: Reporting and database management service of radiological data for clinical trials, Radiologic exam quality control service.

The mission of the Tumor Imaging Metrics Core (TIMC) is to provide standardized, consistent, longitudinal radiological measurements to evaluate therapeutic response for DF/HCC clinical trials. The TIMC - * Makes reliable, quantitative, longitudinal measurements (such as RECIST, WHO, SWOG, standardized uptake value (SUV) etc.) of lesions from serial MRI, CT, PET, and PET/CT scan images * Presents results of analyses on a password-protected secure web-based report * Provides an independent service, with verifiable measurement of treatment response for patients enrolled in cancer center trials * Serves as a centralized, computerized resource to facilitate efficient internal or external auditing Reliable tracking of changes in lesion size or metabolism is essential for clinical trials that use radiological measurements as surrogate endpoints. The Tumor Imaging Metrics Core provides a service for managing these images, making measurements in a routine, reliable, and centralized way, and making results available to investigators efficiently.

Proper citation: DF/HCC Tumor Imaging Metrics Core Facility (RRID:SCR_009744) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-bca3-4116-02c0-2b6880000000

The West Quad Computing Group (WQCG) serves the research community of the BCMP and Cell Biology departments at Harvard Medical School. We provide support for your advanced computing needs, including design and maintenance of computational clusters, large data-set management, web and database backed applications, and workstation support, including workstations connected to research equipment. Please see Resources for more information, including a sample of some of our recent projects. We work in collaboration with the HMS Information Technology department. Please contact us using our support form for all of your computer support needs.

Proper citation: HMS West Quad Computing Group (RRID:SCR_009814) Copy   

•   Source: SciCrunch Registry

http://famu.eagle-i.net/i/00000137-3c2f-98f1-f0f1-ede280000000

Core facility that provides the following services: Animal handling training service, Animal surgery.

Proper citation: FAMU Animal care facility (RRID:SCR_009779) Copy   

•   Source: SciCrunch Registry

https://sites.dartmouth.edu/toxmetal/program-resources/trace-element-analysis/

Analysis of elemental composition of biological tissues and fluids by Inductively Coupled Plasma Mass spectrometry. Analysis of Arsenic species in urine and blood by chromatography-ICP-MS. Laser ablation analysis of tissue sections for imaging of elemental distributions.

Proper citation: Dartmouth Trace Element Analysis Core Facility (RRID:SCR_009777) Copy   

•   Source: SciCrunch Registry

http://dartmouth.eagle-i.net/i/0000012c-3d04-56dc-96ed-bdf580000000

TRAC is affiliated with the the Irradiation and Small Animal Imaging Shared Resource, which together provides irradiation services for basic and translational researchers and state-of-the-art non-invasive in vivo imaging of cultured cells and small animals. Services are used by Dartmouth investigators to irradiate cells in culture and small experimental animals. A separate set of irradiation devices is available through Norris Cotton Cancer Center for clinical and experimental irradiation of human patients.

Proper citation: Dartmouth Translational Research Animal Core (RRID:SCR_009778) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000013a-2c63-ce13-5088-2eef80000000

The SBGrid Core team provides research computing sysadmin support to structural biology laboratories in the Boston area.

Proper citation: HMS SBGrid Core (RRID:SCR_009811) Copy   

•   Source: SciCrunch Registry

http://dartmouth.eagle-i.net/i/0000013f-c93f-101f-0b49-0d2b80000000

Core facility that provides the following services: Research Consulation: Informatics Research.

The Biomedical Informatics Core (BIC) offers clinical and translational investigators support on informatics tools for cohort discovery, data integration, data management, text mining and visual analytics. In addition, the BIC provides consultative services on integration of data systems and on procedures for research data security.

Proper citation: Dartmouth SYNERGY: Biomedical Informatics Core (RRID:SCR_009771) Copy   

•   Source: SciCrunch Registry

http://dartmouth.eagle-i.net/i/0000013f-df6e-7775-8fa3-ce9080000000

Currently under development, the SYNERGY Bioregistry is a centralized virtual biorepository that will integrate information about samples from existing and future biorepositories. The Bioregistry will comprise: A standardized data warehouse of information on existing research biorepositories at Dartmouth eSample, a research tool to allow tracking of specimens and integration with the Bioregistry Access to the Dartmouth freezer farm of large freezer storage units to support archived materials The Bioregistry will enhance access to a diverse array of biologic samples, allowing investigators to manage sample collection and storage based on individual project needs and enabling researchers to learn about existing samples that can be used to pursue new clinical and translational studies. Bioregistry Director: Margaret Karagas, PhD

Proper citation: Dartmouth SYNERGY: Bioregistry (RRID:SCR_009772) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-c7bd-3029-a061-4a6580000000

Core facility that provides the following services: Enzyme-linked immunosorbent spot assay service, Fluorescence microscopy service, Real-time PCR Service.

The NERCE Microbiology and Animal Resources Core maintains two laboratories, a BSL-2 and a BSL-3 laboratory, to support the research efforts of all New England investigators conducting research on NIAID priority pathogens. Each laboratory provides the physical environment, equipment, and support personnel required for scientists to work with these agents. The BSL-3 laboratory is an isolated suite that includes individual laboratory rooms and rooms for housing experimental animals, all within a single containment facility. The BSL-3 lab provides the extensive security and administrative support structure required for possession of CDC select agents. The laboratory acquires strains of viruses and bacteria, prepares seed stocks, and characterizes these seed stocks using phenotypic and molecular methods to ensure a well-characterized, pure biological reagent. Laboratory staff members assist investigators with experiments involving pathogen culture, fractionation of biological material, animal challenge, and vaccine and drug administration. The laboratory is equipped for commonly used analytical methods, including fluorescence microscopy, PCR, EIA, and ELISPOT. A single suite with both laboratory and experimental animal capability eliminates the need to transport infectious material between laboratories. The BSL-2 laboratory provides support required by the BLS-3 facility, access to attenuated strains exempt from select agent registration, and laboratory space for visiting investigators. Investigators interested in working with the Microbiology and Animal Resources core laboratory should complete the Core A Request Form and send it to Christine Anderson. See lab website for details. There are no charges for projects focused on NIAID priority pathogens and agents of emerging infectious disease.

Proper citation: HMS NERCE Microbiology and Animal Resources Core (RRID:SCR_009807) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-c7a7-e0e5-a061-4a6580000000

Core facility that provides the following services: Protein production, Bacterial fermentation for recombinant protein production, Baculovirus culture, Protein purification.

The NERCE Biomolecule Production Core Laboratory is a core service laboratory with capability for expression and purification of recombinant proteins using bacterial and baculoviral expression systems, and preparation of bacterial carbohydrate components. It supports all New England investigators conducting research on NIAID priority pathogens that requires purified proteins or carbohydrates. Investigators are expected to provide data demonstrating efficacy of production and purification methods, as well as strains or purified recombinant plasmid preparations where applicable. See lab website for details. Please note that since the NERCE program will end in February 2014, our ability to support new requests for services is limited.

Proper citation: HMS NERCE Biomolecule Production Core Laboratory (RRID:SCR_009804) Copy   

•   Source: SciCrunch Registry

http://dartmouth.eagle-i.net/i/0000013f-df4e-eedf-8fa3-ce9080000000

Core facility that provides the following services: Comprehensive, Expert Recruitment and Retention support.

The Recruitment and Retention Core (RCC) helps investigators make their studies visible across Dartmouth and to the public to increase awareness of clinical study opportunities. RRC Director: Sheila B. Noone, PhD

Proper citation: Dartmouth SYNERGY: Recruitment and Retention Core (RRID:SCR_009768) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012b-00c3-845c-db6e-7a3f80000000

Core facility that provides the following services: Soft-lithography service, Soft-lithography training and consultation.

The HMS Microfluidics Facility aims to make the tools of Microfabrication and Microfluidics available to all HMS users.

Proper citation: HMS Microfluidics Core Facility (RRID:SCR_009801) Copy   

•   Source: SciCrunch Registry

http://dartmouth.eagle-i.net/i/0000013f-cf7e-df45-0b49-0d2b80000000

The Research Design and Epidemiology Core (RDE) provides consultation and guidance to investigators at the earliest stages of their study design.

Proper citation: Dartmouth SYNERGY: Research Design and Epidemiology Core (RRID:SCR_009769) Copy   

•   Source: SciCrunch Registry

http://dartmouth.eagle-i.net/i/00000140-0bdb-4fa0-785a-dfc280000000

Core facility that provides the following services: Data and Analysis of large health care datasets.

The Data and Analytic Core (DAC) includes research analysts and programmers, research assistants, a data librarian, and a Director who reports to the Director of the Center for Health Policy Research and the DAC Advisory Committee. The DACs responsibilities are to maintain an extremely secure environment for health care datasets provided to Principal Investigators by the U.S. Centers for Medicare and Medicaid Services, state governments, and other organizations under data use agreements and licenses. The DAC works under the direction of faculty investigators who have specific permission to use the data to conducted research. The DAC consists of 15 analysts (and an additional 5 staff) with a combined 150 years of healthcare claims analytic experience and a mastery of a broad range of programming and statistical methods. New analysts undergo a comprehensive training program lasting the better part of 6 months to assure a strong foundation in Medicare data analytics.

Proper citation: Dartmouth Institute for Health Policy and Clinical Practice: Data and Analytic Core (RRID:SCR_009764) Copy   

•   Source: SciCrunch Registry

http://dartmouth.eagle-i.net/i/0000012e-5d0c-3250-a694-4a4a80000000

Core facility that provides the following services: Coding of data. The Dartmouth Media Research Lab (DMRL) specializes in the content coding of all types of media including movies, television programming and advertising. We have an extensive database of top box office hits from 1995 to the present. Past areas of research have included tobacco, alcohol, food, violence, and sexual activity. The team consists of two trained coders and a supervisor who ensures consistency and reliability.

Proper citation: Dartmouth Media Research Lab Shared Resource (RRID:SCR_009765) Copy   

•   Source: SciCrunch Registry