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http://www.brainbank.nl

A biomaterial supply resource which collects, stores, and disseminates diseased and healthy brain tissue. The Netherlands Brain Bank currently contains more than 3600 samples, and each sample includes a neuropathological report and donor medical history. The samples can additionally be matched with ante-mortem parameters and post-mortem parameters upon request. Sample types include cortex, spinal cord, cerebrospinal fluid, plasma, and DNA, among others. Database mining is available with a financial contribution.

Proper citation: Netherlands Brain Bank (RRID:SCR_013841) Copy   

•   Source: SciCrunch Registry

http://www.ncl.ac.uk/ion/about/facilities/nbtr/

A biomaterial supply resource which archives and disseminates brain tissue for the study of normal brain aging and brain disorders. Researchers must create an account in order to browse the database of available tissue. Samples are distributed to researchers in such a way that the identity and personal information of donors is protected.

Proper citation: Newcastle Brain Tissue Resource (RRID:SCR_013843) Copy   

•   Source: SciCrunch Registry

http://www.flinders.edu.au/sabs/fcas/alsa/alsa_home.cfm

The general purpose of ALSA is to examine how social, biomedical, psychological, economic, and environmental factors are associated with age-related changes in the health and wellbeing of persons aged 70 years and older. The aim is to analyze the complex relationships between individual and social factors and changes in health status, health care needs and service utilization dimensions, with emphasis given to the effects of social and economic factors on morbidity, disability, acute and long-term care service use, and mortality. The study was designed to have common instrumentation with US studies. ALSA collected data from a random, stratified sample of all persons (both community and institution-dwelling) aged 70 years and older living in the metropolitan area of Adelaide, South Australia, using the State Electoral Database as the sampling frame. Spouses aged 65 and older and other household members aged 70 years and older also were invited to participate. The initial baseline data collection for ALSA began in September 1992 and was completed in March 1993. In the first wave, personal interviews were carried out for 2,087 participants, including 566 couples (that is, persons 70 years of age and over and their spouse, if 65 and over). Clinical assessments were obtained for 1,620 of the participants. Respondents were recontacted by telephone a year after initial interview (wave 2). The third wave of the study began in September 1994 and involved a complete reassessment, with a total of 1,679 interviews and 1,423 clinical assessments. To date, eleven waves of data have been collected, with the latest collection in May 2010, from 168 participants. Six of these waves were conducted via face-to-face interviews and clinical assessments, and five were telephone interviews. Future waves are planned, however are dependent on grant funding. Ancillary data collection has been ongoing since the initiation of the study, e.g., from secondary providers. Lists of ALSA participants are compared biannually with the agencies'' lists to determine the prevalence and incidence of receipt of services from these organizations. Another source of information has been the collection of data from the participants'' general practitioners about the respondent''s health status, history of services received, medication use, referrals to specialists, and current services provided. Baseline Sample Size: 2087 Dates of Study: 1992����������2010 (potentially ongoing) Study Features: * Longitudinal * International * Anthropometric Measures * Biospecimens Waves 1-5 (ICPSR), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06707 Wave 6 (ICPSR), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/03679

Proper citation: ALSA - The Australian Longitudinal Study of Ageing (RRID:SCR_013146) Copy   

•   Source: SciCrunch Registry

http://www.tcd.ie/IMM/trinity-biobank/index.php

The Trinity Biobank was established in 2005 to serve the needs of researchers in the area of genetic epidemiology, population genetics and pharmacogenomics. Its services are available to researchers not only in Trinity College but to other institutions at home and abroad. We provide an automated DNA extraction service purifying large volumes blood (up to 10mL whole blood) and tissue DNA for archival and other purposes. In addition it makes available purified DNA and associated GWAS data from 2000 healthy donors for research use. A key requirement for reliable downstream use of DNA is purity and strand size. The quality of DNA in blood and tissue deteriorates upon storage without purification even at -80 degrees C. We ensure rapid turnaround of biological samples through automated extraction using the Qiagen Autopure system based on optimized ''salting out'' chemistry. The purified DNA sample may then be stored safely at -20 degrees C without deterioration thus freeing up valuable -80 degree C freezer space and the associated capital and maintenance cost as well as security and lab space provision. Automated DNA extraction is particularly suitable for high-throughput sample processing called for in epidemiological studies or simply for clearing sample inventory backlogs. The Trinity Biobank distributes control DNA to researchers as part of its remit to enhance the level of research activity and to synergize molecular medicine research nationally and internationally. The buffy coat collection has been made possible with the cooperation of the Irish Blood Transfusion Service (IBTS). An important requirement to access the collection is that the use of the samples relates only to ethically-approved research and to specifically-nominated research projects. The DNA collection consists of high quality human genomic DNA. Each of the available 2,000 samples is from a single individual and each sample comes with the age and gender data of the donor. The buffy coat sample is derived from the total white cell compliment (50mL buffy coat) of a blood donation (c 400mL). We will endeavor to fulfill samples number requests based on age and gender as best as possible. This collection has also been genotyped using the Affymetrix Genome-Wide Human SNP Array 6.0, featuring 1.8 million genetic markers, including more than 906,600 single nucleotide polymorphisms (SNPs) and more than 946,000 probes for the detection of copy number variation (CNV). The DNA comes available as a 100ng/uL in 100uL of TE Buffer, ie in 10ug amounts in a separate screw-cap ampoule. The ampoules are shipped in 100-tube boxes (Sarstedt). Corresponding plasma (ACD) is also available on request. Genotype data is supplied in PLINK binary PED files format (http://pngu.mgh.harvard.edu/~purcell/plink/ ).

Proper citation: Trinity Biobank (RRID:SCR_013279) Copy   

•   Source: SciCrunch Registry

http://www.emcdda.europa.eu/eib

The EIB provides assessment tests for substance disorder related clinical instruments that are freely available. Details regarding copyright and/or possible use restrictions are specified for each instrument. Instruments are generally classed according to the intervention field they are designed to be used in (treatment, prevention, or harm reduction), though some instruments may be usable in more than one field.

Proper citation: Evaluation Instruments Bank (RRID:SCR_013246) Copy   

•   Source: SciCrunch Registry

http://sites.duke.edu/dhhr/

A biomaterial supply resource which collects and disseminates human heart tissue. Samples include both failing and non-failing hearts, RNA/DNA analysis, tissue staining and immunofluorescence samples.The tissue that has been flash frozen and stored at -80˚C is acquired from distinct regions of the heart such as the LV free wall, septum, and valve leaflets. Individual sample sizes are typically 100-300mg for flash frozen tissues. The DHHR also serves as a resource for assay development, target identification, and sponsored research, capable of isolating cardiomyocytes from hearts and using them for in-vitro assays such as calcium handling, enzyme activity, signalling pathways and other biochemical research activities

Proper citation: Duke Human Heart Repository (RRID:SCR_013980) Copy   

•   Source: SciCrunch Registry

http://www.compudrug.com/toxalert

Software tool for high-throughput toxicity prediction; it assists in the early and quick identification of toxic drug candidates. ToxAlert provides probability percentages for different toxicity endpoints such as oncogenicity, mutagenicity, teratogenicity, neurotoxicity or cell toxicity.

Proper citation: ToxAlert (RRID:SCR_014907) Copy   

•   Source: SciCrunch Registry

https://www.thermofisher.com/order/catalog/product/IQLAAEGAAPFADBMBCX

Mass spectrometer that combines quadrupole, ion trap, and Orbitrap mass analysis.

Proper citation: LTQ-Orbitrap Fusion Tribrid Mass Spectrometer (RRID:SCR_014992) Copy   

•   Source: SciCrunch Registry

https://www.nikoninstruments.com/en_EU/Products/Upright-Microscopes/Research/Eclipse-FN1

Fixed-stage microscope for electrophysiological research. Features include open design, noise reduction, 16x objective lens, and water dipping objective with depth induced aberration correction.

Proper citation: Nikon: Eclipse FN1 Microscope (RRID:SCR_014995) Copy   

•   Source: SciCrunch Registry

https://addictionresource.com

Private organization that offers resources and serves as a community for those recovering from addiction and to help patients find the highest quality care for a successful recovery.

Proper citation: AddictionResources (RRID:SCR_015048) Copy   

•   Source: SciCrunch Registry

https://www.agilent.com/cs/library/datasheets/Public/5991-2541EN.pdf

Hardware system which automates RNA, DNA, and protein sample QC, including sample loading, separation, and imaging.

Proper citation: Agilent: 2200 TapeStation Instrument (RRID:SCR_014994) Copy   

•   Source: SciCrunch Registry

http://www.cepal.org

Regional commission of the United Nations with the purpose of contributing to the economic development of Latin America, coordinating actions directed towards this end, reinforcing economic ties among countries and with other nations, and promoting social development.

Proper citation: Economic Commission for Latin America and the Caribbean (RRID:SCR_014998) Copy   

•   Source: SciCrunch Registry

http://www.multicase.com/meta-pc

Software program to predict metabolic and degradation products of chemicals. METAPC has dictionaries on mammalian metabolism, aerobic microbial degredation, anerobic microbial degredation, and photo degredation.

Proper citation: METAPC (RRID:SCR_014916) Copy   

•   Source: SciCrunch Registry

https://support.illumina.com/sequencing/sequencing_software/bcl2fastq-conversion-software.html

Conversion software developed by Illumina that both demultiplexes data and converts BCL files generated by Illumina sequencing systems to standard FASTQ file formats for downstream analysis.

Proper citation: bcl2fastq (RRID:SCR_015058) Copy   

•   Source: SciCrunch Registry

http://www.oif.org

Foundation for improving the quality of life for people affected by OI through treatment and cure research, education, awareness, and mutual support. OIF lists personal resources for individuals affected by osteogenesis imperfecta as well as professional and clinical resources for researchers.

Proper citation: Osteogenesis Imperfecta Foundation (RRID:SCR_015034) Copy   

•   Source: SciCrunch Registry

https://www.cdc.gov/labstandards/index.html

Standardization program which helps assure the quality of laboratory test data and results so patients, healthcare providers, researchers, and public health officials can be confident that laboratory test results they receive are accurate. CDC services include reference materials, proficiency testing, training, guideline creation, and consultations. Quality assurance and standardization programs can be can be customized by and for users and laboratories.

Proper citation: CDC Laboratory Quality Assurance and Standardization Programs (RRID:SCR_015000) Copy   

•   Source: SciCrunch Registry

https://www.keyence.co.jp/products/microscope/fluorescence-microscope/bz-9000/models/bz-9000/

Microscope system performs fluorescence, bright-field and phase-contrast imaging on various specimen holders. The system allows users to switch between four fluorescent channels, automatically adjusting the filter and exposure time while preserving the longevity of the specimen.

Proper citation: BZ 9000 Fluorescence Microscope (RRID:SCR_015486) Copy   

•   Source: SciCrunch Registry

http://spectrumlabs.com/

Commercial organization which supplies products for bioseparation and cell line management.

Proper citation: Spectrum Labs (RRID:SCR_015488) Copy   

•   Source: SciCrunch Registry

https://www.bsc.es/marenostrum/marenostrum

Operating software for a supercomputer in Spain. The software is maintained and updated by the Centro Nacional de Supercomputación (Barcelona Supercomputing Center) and is used for research projects on climate change, gravitational waves, a vaccination against AIDS, new radiation treatments to fight cancer, and other subjects.

Proper citation: MareNostrum (RRID:SCR_015737) Copy   

•   Source: SciCrunch Registry

http://amp.pharm.mssm.edu/archs4/

ARCHS4 provides access to gene counts from HiSeq 2000 and HiSeq 2500 platforms for human and mouse experiments from GEO and SRA. The website enables downloading of the data in H5 format for programmatic access as well as a 3-dimensional view of the sample and gene spaces. Search features allow browsing of the data by meta data annotation, ability to submit your own up and down gene sets, and explore matching samples enriched for annotated gene sets. Selected sample sets can be downloaded into a tab separated text file through auto-generated R scripts for further analysis. Reads are aligned with Kallisto using a custom cloud computing platform. Human samples are aligned against the GRCh38 human reference genome, and mouse samples against the GRCm38 mouse reference genome.

Proper citation: ARCHS4 (RRID:SCR_015683) Copy   

•   Source: SciCrunch Registry