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Mesial temporal lobe measurements on magnetic resonance imaging scans.

Changes in the mesial temporal lobe, particularly in the hippocampus, amygdala, and entorhinal cortex, are reported to occur in several neuropsychiatric conditions. Neuroimaging provides a non-invasive means of studying these changes. We present a method for reliably measuring the hippocampus, amygdala, and entorhinal cortex on MRI. The advantages of our method include high reliability, the use of orthogonal views in delineating boundaries and circumscription of measurement such that no tissue of any one anatomic structure is included in the measurement of another structure.

Pubmed ID: 9818734


  • Honeycutt NA
  • Smith PD
  • Aylward E
  • Li Q
  • Chan M
  • Barta PE
  • Pearlson GD


Psychiatry research

Publication Data

August 26, 1998

Associated Grants


Mesh Terms

  • Amygdala
  • Anatomy, Cross-Sectional
  • Biometry
  • Entorhinal Cortex
  • Hippocampus
  • Humans
  • Image Processing, Computer-Assisted
  • Limbic System
  • Magnetic Resonance Imaging
  • Observer Variation
  • Temporal Lobe