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No difference in hippocampus volume detected on magnetic resonance imaging in autistic individuals.

Neuropathological and animal studies have implicated the hippocampus as having a potential role in autism. Current imaging methods are well suited to the detailed measurement of the volume of the hippocampus, which has received little attention in previous imaging studies in autism. We report the results of a magnetic resonance imaging (MRI) study of 35 autistic and 36 control subjects. Detailed (1.5 mm) MRI did not reveal differences in the volume of the hippocampus in autistic individuals.

Pubmed ID: 9586772


  • Piven J
  • Bailey J
  • Ranson BJ
  • Arndt S


Journal of autism and developmental disorders

Publication Data

April 4, 1998

Associated Grants

  • Agency: NIMH NIH HHS, Id: MH01028
  • Agency: NIMH NIH HHS, Id: MH40856
  • Agency: NIMH NIH HHS, Id: MH51217

Mesh Terms

  • Adolescent
  • Adult
  • Autistic Disorder
  • Female
  • Hippocampus
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Neuropsychological Tests