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Software for constructing and verifying pedigrees within large genealogies and an application to the Old Order Amish of Lancaster County.

This paper describes PedHunter, a software package that facilitates creation and verification of pedigrees within large genealogies. A frequent problem in medical genetics is to connect distant relatives with a pedigree. PedHunter uses methods from graph theory to solve two versions of the pedigree connection problem for genealogies as well as other pedigree analysis problems. The pedigrees are produced by PedHunter as files in LINKAGE format ready for linkage analysis. PedHunter uses a relational database of genealogy data, with tables in specified format, for all calculations. The functionality and utility of PedHunter are illustrated by examples using the Amish Genealogy Database (AGDB), which was created for the Old Order Amish community of Lancaster County, Pennsylvania.

Pubmed ID: 9521925

Authors

  • Agarwala R
  • Biesecker LG
  • Hopkins KA
  • Francomano CA
  • Schaffer AA

Journal

Genome research

Publication Data

March 11, 1998

Associated Grants

  • Agency: NHGRI NIH HHS, Id: P01HG00373

Mesh Terms

  • Christianity
  • Computer Graphics
  • Databases, Factual
  • Female
  • Genetics, Medical
  • Genetics, Population
  • Humans
  • Inbreeding
  • Information Storage and Retrieval
  • Male
  • Pedigree
  • Pennsylvania
  • Software