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Myodystrophy, a new myopathy on chromosome 8 of the mouse.

The Journal of heredity | Sep 25, 1976

http://www.ncbi.nlm.nih.gov/pubmed/939913

A new recessive mutation, myd, causing a diffuse and progressive myopathy in the mouse is described. Histopathological comparisons with normal littermates showed widely distributed focal lesions in all skeletal muscles of myd/myd. Body and organ weights of affected mice were considerably less than those of normal littermates and the mean lifespan of myodystrophic mice that survived weaning was 17 weeks with a range of 5 to 39 weeks. Myodystrophy is located on chromosome 8; it is linked to Os with about 6 percent and to Eso with about 37 percent recombination.

Pubmed ID: 939913 RIS Download

Mesh terms: Animals | Chromosome Mapping | Crosses, Genetic | Female | Genes | Genes, Recessive | Genetic Linkage | Male | Mice | Muscular Diseases | Mutation | Phenotype | Pigmentation | Rodent Diseases

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Mouse Genome Informatics (Data, Gene Annotation)

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