• Register
X
Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.

X

Leaving Community

Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.

No
Yes

Interaction of human recombination proteins Rad51 and Rad54.

The cDNA for human protein HsRad54, which is a structural homolog of Saccharomyces cerevisiae recombination/repair protein Rad54, was cloned and expressed in Escherichia coli. As demonstrated by analysis in vitro and in vivo, HsRad54 protein interacts with human Rad51 recombinase. The interaction is mediated by the N-terminal domain of HsRad54 protein, which interacts with both free and DNA-bound HsRad51 protein.

Pubmed ID: 9321665

Authors

  • Golub EI
  • Kovalenko OV
  • Gupta RC
  • Ward DC
  • Radding CM

Journal

Nucleic acids research

Publication Data

October 15, 1997

Associated Grants

  • Agency: NCI NIH HHS, Id: 5PO1 CA3923809
  • Agency: NIGMS NIH HHS, Id: 5R37 GM3350413

Mesh Terms

  • Blotting, Western
  • Cloning, Molecular
  • DNA
  • DNA Helicases
  • DNA Repair Enzymes
  • DNA-Binding Proteins
  • Drug Interactions
  • Escherichia coli
  • Fungal Proteins
  • Gene Expression
  • Humans
  • Peptide Fragments
  • Rad51 Recombinase
  • Recombinant Proteins
  • Saccharomyces cerevisiae
  • Saccharomyces cerevisiae Proteins