• Register
Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.


Leaving Community

Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.


'Green mice' as a source of ubiquitous green cells.

The green fluorescent protein (GFP) is responsible for the green bioluminescence of the jellyfish Aequorea victoria. Many classes of GFP mutants exist that display modified fluorescence spectra and an increased extinction coefficient. We produced transgenic mouse lines with an 'enhanced' GFP (EGFP) cDNA under the control of a chicken beta-actin promoter and cytomegalovirus enhancer. All of the tissues from these transgenic lines, with the exception of erythrocytes and hair, were green under excitation light. The fluorescent nature of the cells from these transgenic mouse lines would facilitate their use in many kinds of cell transplantation experiments.

Pubmed ID: 9175875


  • Okabe M
  • Ikawa M
  • Kominami K
  • Nakanishi T
  • Nishimune Y


FEBS letters

Publication Data

May 5, 1997

Associated Grants


Mesh Terms

  • Actins
  • Animals
  • Cell Separation
  • Cell Transplantation
  • Chickens
  • Cytomegalovirus
  • Enhancer Elements, Genetic
  • Female
  • Flow Cytometry
  • Fluorescence
  • Genes, Reporter
  • Green Fluorescent Proteins
  • Luminescent Proteins
  • Male
  • Mice
  • Mice, Transgenic
  • Pregnancy
  • Promoter Regions, Genetic
  • Scyphozoa
  • Tissue Distribution